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Publications (2)3.76 Total impact

  • H L Dameshek · L D Ellis
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    ABSTRACT: The current presentation addresses autoimmune hematologic disorders, congenital hemolytic states, thrombotic thrombocytopenic purpura, staging procedures for 'lymphomas', and, ultimately miscellaneous indications for splenectomy. Hypersplenism, of both primary and secondary types, is an important indication for splenic removal. The purpose of this review has been to present the surgeon with a clearer understanding of these disease states and to allow him to make a more knowledgeable decision regarding the need for splenectomy in their immediate management. The intelligent decision must include a consideration of the surgical risks in each individual patient, and weighing of the possible beneficial effects from its performance. In general, the operative risk in most patients is low in the hands of an experienced surgeon. We have been impressed with the relatively low incidence of surgical complications and near absent mortality in the large number of our hematologic patients subjected to splenectomy at our institution.
    No preview · Article · May 1975 · Surgical Clinics of North America
  • L D Ellis · H L Dameshek
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    ABSTRACT: The dilemma of hypersplenism is not resolved, but there is a clearer understanding of the pathogenesis of this syndrome. Once hypersplenism is established in a patient, the indications for splenectomy are dependent upon the primary disease process and the associated prognosis. There is an increasing tendency for early splenectomy in primary hypersplenism and in secondary hypersplenism associated with the non Hodgkin's lymphomas of the well differentiated lymphocytic variety. Each patient with the syndrome of hypersplenism must be evaluated individually and the decision for splenectomy made only after careful hematologic and medical investigation and an informed dialogue between the surgeon and the hematologist.
    No preview · Article · May 1975 · Surgical Clinics of North America

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18 Citations
3.76 Total Impact Points

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