[Show abstract][Hide abstract] ABSTRACT: LiOH has been found to be a very simple and selective catalyst for the rapid and mild synthesis of β-hydroxy sulfides and β-hydroxyl nitriles by ring opening of epoxides with aromatic, aliphatic, and heterocyclic thiols and trimethylsilyl cyanide at room temperature under solvent free conditions. All the reactions proceeded satisfactorily in short times and afforded the corresponding products in good to excellent yields with high regioselectivity and chemoselectivity under mild reaction conditions.
No preview · Article · Jul 2010 · Phosphorus Sulfur and Silicon and the Related Elements
[Show abstract][Hide abstract] ABSTRACT: An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and tedious work-up.
No preview · Article · Feb 2010 · Molecular Diversity
[Show abstract][Hide abstract] ABSTRACT: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
[Show abstract][Hide abstract] ABSTRACT: The rapid and very simple conjugate addition of thiols to α,β-unsaturated carbonyl compounds under solvent-free conditions in the presence of catalytic amount of lithium hydroxide at room temperature is reported. The reaction of aryl, alkyl, aliphatic, and hindered thiols with chalcone, enone, and nitrostyrene gave the corresponding Michael adducts with significant advantages, such as high conversions, short reaction time, mild reaction conditions, low cost, simple catalyst, and high to quantitative yields with excellent chemoselectivity.
No preview · Article · Sep 2009 · Green Chemistry Letters and Reviews
[Show abstract][Hide abstract] ABSTRACT: An operationally simple, practical, and economical protocol for iron(III) chloride catalyzed Paal-Knorr pyrrole synthesis in water in good to excellent yields has been developed. Several N-substituted pyrroles are readily prepared from the reaction of 2,5-dimethoxytetrahydrofuran and aryl/alkyl, sulfonyl and acyl amines under very mild reaction conditions