Z N Xi

Beijing Tiantan Hospital, Peping, Beijing, China

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Publications (3)3.21 Total impact

  • L. Xu · P.-Y. Gao · Y. Lin · J.-C. Han · Z.-N. Xi · H. Shen
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    ABSTRACT: Objective: To investigate the potential values of magnetic resonance elastography (MRE) for evaluating the brain tumor consistency in vivo. Methods: Fourteen patients with known solid brain tumor (5 male, 9 female; age range: 16 - 63 years) underwent brain MRE studies. Informed consent was obtained from all patients. A dedicated external force actuator for brain MRE study was developed. The actuator was fixed to the head coil. During scan, one side of the actuator was attached to the patients' head. Low frequency oscillation was produced by the actuator and caused shear waves propagating into brain tissue. The pulse sequence used in the study was phase-contrast gradient-echo sequence. Phase images of the brain were obtained and the shear waves within the brain were directly imaged. Phase images were processed with local frequency estimation (LFE) technique to obtain the elasticity image. Consistency of brain tumors was evaluated at surgery and was classified as soft, intermediate, or hard with comparison to the white matter of the brain. Correspondence of MRE evaluation with operative results was studied. Results: The elastic modulus of the tumor was lower than that of white matter in 1 patient, higher in11 patients, and similar in 2 patients. At surgery, the tumor manifested a soft consistency in 1 patient, hard consistency in 11 patients, intermediate consistency in 2 patients. The elasticity of tumors in 14 patients evaluated by MRE was correlated with the tumor consistency on the operation. Conclusion: MRE can noninvasively display the elasticity of brain tumors in vivo, and evaluate the brain tumor consistency before operation.
    No preview · Article · Jun 2008
  • L Xu · Y Lin · J C Han · Z N Xi · H Shen · P Y Gao
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    ABSTRACT: To investigate the potential value of magnetic resonance elastography (MRE) in evaluating the consistency of brain tumors. Six patients with known solid brain tumor underwent brain MRE studies. Consistency of brain tumors was evaluated at surgery. Correspondence of MRE evaluation with operative result was studied. The elasticity of tumors in six patients evaluated by MRE agreed with the tumor consistency given by the operative results. MRE could be used as an imaging technique for noninvasive assessment of the consistency of brain tumor in vivo.
    No preview · Article · May 2007 · Acta Radiologica
  • L Xu · Y Lin · Z N Xi · H Shen · P Y Gao
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    ABSTRACT: To study the application of magnetic resonance elastography (MRE) in the human brain. An external force actuator was developed, which produced propagating shear waves in brain tissue. A modified phase-contrast gradient-echo sequence was developed. The propagating shear waves within the brain were directly imaged. The wave images were processed to obtain the elasticity image. Shear waves at 100 Hz, 150 Hz, and 200 Hz were applied. The propagating shear waves in the brain were visualized on wave images. The elasticity image revealed the difference in tissue elasticity between gray and white matter of the brain. MRE could be an imaging technique for assessing the elasticity of brain tissue.
    No preview · Article · Mar 2007 · Acta Radiologica

Publication Stats

77 Citations
3.21 Total Impact Points

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Institutions

  • 2007
    • Beijing Tiantan Hospital
      Peping, Beijing, China