[Show abstract][Hide abstract] ABSTRACT: We report a retrospective study of 15 cases of pyoderma gangrenosum. The male/female ratio was 2, average age 40 years (range: 2-48 years). The typical ulcerous form was observed in 11 patients, whereas bullous pyodrma gangrenosum was noted in 2 patients and the granulomatous superficial form in 2 others. The leg was the most frequent localization. It was often associated with another skin localization. Two patients had neutrophilic pulmonary involvement which was concomitant to the skin ulcers. Association with internal disease was found in 8 patients. Histology showed vasculitis in 11 patients. In 9 of them, leukocytoclastic vasculitis was observed. Prednisone and clofazimine were the most frequently prescribed drugs. Th rate of recurrence of pyoderma gangrenosum was 46% independently of treatment. Occurrence of neutrophilic pneumopathy was rapidly fatal in two of our patients
No preview · Article · Mar 2001 · Annales de medecine interne
[Show abstract][Hide abstract] ABSTRACT: Cutaneous metastases from internal tumours are relatively rare. They may represent the first evidence of malignancy or appear during a known neoplastic disease. Cutancous metastases generally manifest as solitary or multiple nodules over the head, chest and abdominal wall. They are mainly due to cancers of the breast in women or of pulmonary origin in men. Their occurence usually has omnious prognostic significance and considerably reduces the chances for efficient treatment. The authors report eighteen cases of cutaneous metastases from internal tumours. The sex- ratio was 12M/6F. The mean age was 62 years (33 - 84). The clinical manifestation was mainly multiple nodules (61 %). The chest (33 %) and the abdominal wall (27 %) were the most frequent localisations. The primary internal cancers are pulmonary in 41 % of men and mammary in 66 % of women. Intestinal cancers are present in 16 % of all patients.
No preview · Article · Jan 1999 · Nouvelles Dermatologiques
[Show abstract][Hide abstract] ABSTRACT: The tinea versicolor is a frequency superficial mycosis. The treatment is essentially local. Sixty patients was treated by Ketoconazole 2% foaming gel. At day 30 of treatment 41.5% responded clinically and there was 87.5% mycologic cure rate. The treatment is well tolorated in 44/48 patients. This study indicate the efficacy of Ketoconazole foaming gel in single application in treatment of tinea versicolor.
No preview · Article · Jan 1999 · La Tunisie médicale