F Neczyporenko

Université Libre de Bruxelles, Bruxelles, Brussels Capital Region, Belgium

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Publications (3)7.16 Total impact

  • F Neczyporenko · J André · K Torosian · A Theunis · B Richert
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    ABSTRACT: Background Nail apparatus melanoma (NAM) is a rare melanocytic neoplasm with pejorative prognosis often related to late diagnosis. Early diagnosis at in situ stage (NAMis) is difficult, but essential to improve prognosis. NAMis management is not well established yet. Removal of the whole nail unit has been advocated in several small series as a potential treatment for NAMis. Objective To report and assess functional' or conservative' surgery for NAMis and evaluate its long-term oncologic safety. Methods Retrospective study of cases diagnosed in the University Hospital Saint-Pierre collected over a 13year period and compared with the published data. ResultsEleven cases of NAMis were identified: 73% concerned females. Thumb and first toe were the most affected digits (63% of total). Monodactylic longitudinal melanonychia (LM) was the most frequent presentation (92%). Mean diagnosis delay was 5years. Diagnosis was suspected on the basis of clinical and dermatoscopic signs and was confirmed by pathological examination. All patients underwent complete nail unit removal with 6mm security margins around the anatomic boundaries of the nail. Two late local recurrences were observed at 7 and 11years follow-up. Conclusions Our series, the largest up to now, demonstrates that functional surgery' is a rational approach for NAMis with an excellent oncologic safety at 5years. However, this study suggests that a very long-term follow-up is mandatory, as recurrences may appear late.
    No preview · Article · Mar 2013 · Journal of the European Academy of Dermatology and Venereology
  • Florence Neczyporenko · Arlette Blondeel

    No preview · Article · Sep 2010 · Contact Dermatitis
  • C Martin · F Neczyporenko · S De Wit
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    ABSTRACT: Pyoderma gangrenosum is a rare, chronic, non infectious ulcerative skin disease. It is an inflammatory neutrophilic dermatosis. It is associated in 50% with a systemic disorder. Unfortunately, there are no randomized controlled studies concerning PG treatment. Immunosuppression is the mainstay of treatment and includes local and systemic measures, with high risk of potential side effects. Multidisciplinary care to patients with PG is essential for best management. We present a patient with pyoderma gangrenosum which was admitted in our Infectious Diseases Unit and first treated based on an infectious assumption. Collaboration between internists and dermatologists led to quick correct diagnosis, PG management, exclusion of an associated systemic disorder and management of further complications.
    No preview · Article · Jul 2010 · Acta clinica Belgica