Robert T Medler

The University of Arizona, Tucson, Arizona, United States

Are you Robert T Medler?

Claim your profile

Publications (1)3.67 Total impact

  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Campylobacter jejuni is a major cause of human diarrheal disease in many industrialized countries and is a source of public health and economic burden. C. jejuni, present as normal flora in the intestinal tract of commercial broiler chickens and other livestock, is probably the main source of human infections. The presence of C. jejuni in biofilms found in animal production watering systems may play a role in the colonization of these animals. We have determined that C. jejuni can form biofilms on a variety of abiotic surfaces commonly used in watering systems, such as acrylonitrile butadiene styrene and polyvinyl chloride plastics. Furthermore, C. jejuni biofilm formation was inhibited by growth in nutrient-rich media or high osmolarity, and thermophilic and microaerophilic conditions enhanced biofilm formation. Thus, nutritional and environmental conditions affect the formation of C. jejuni biofilms. Both flagella and quorum sensing appear to be required for maximal biofilm formation, as C. jejuni flaAB and luxS mutants were significantly reduced in their ability to form biofilms compared to the wild-type strain.
    Preview · Article · Apr 2007 · Applied and Environmental Microbiology

Publication Stats

79 Citations
3.67 Total Impact Points


  • 2007
    • The University of Arizona
      • Department of Veterinary Sciences and Microbiology
      Tucson, Arizona, United States