Mustafa Saka

Ankara Numune Training and Research Hospital, Engüri, Ankara, Turkey

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Publications (15)19.64 Total impact


  • No preview · Article · Jan 2014 · European Journal of General Medicine
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    ABSTRACT: A 36 years old male patient developed bilateral foot drop after starting an intensive weight loss programme. Diagnosis of bilateral peroneal nerve palsy was confirmed using nerve conduction studies and electromyography. After physical therapy and a diet modification, his symptoms resolved in a few months. Weight loss is a known risk factor for the development of neuropathy at the fibular head because of fat loss previously protecting the common peroneal nerve against compression. However bilateral involvement of peroneal nerves is very rare. Physicians should keep in mind peroneal neuropathy as a complication of weight loss. In this case, diet modification and physical therapy might be a reasonable method before surgery.
    Full-text · Article · Dec 2013 · Journal of Neurological Sciences
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    ABSTRACT: Aim . This study compares the effectiveness of Michigan Neuropathy Screening Instrument (MNSI), neurothesiometer, and electromyography (EMG) in detecting diabetic peripheral neuropathy in patients with diabetes type 2. Materials and Methods . 106 patients with diabetes type 2 treated at the outpatient clinic of Ankara Numune Education and Research Hospital Department of Endocrinology between September 2008 and May 2009 were included in this study. Patients were evaluated by glycemic regulation tests, MNSI (questionnaire and physical examination), EMG (for detecting sensorial and motor defects in right median, ulnar, posterior tibial, and bilateral sural nerves), and neurothesiometer (for detecting alterations in cold and warm sensations as well as vibratory sensations). Results . According to the MNSI score, there was diabetic peripheral neuropathy in 34 (32.1%) patients (score ≥2.5). However, when the patients were evaluated by EMG and neurothesiometer, neurological impairments were detected in 49 (46.2%) and 79 (74.5%) patients, respectively. Conclusion . According to our findings, questionnaires and physical examination often present lower diabetic peripheral neuropathy prevalence. Hence, we recommend that in the evaluation of diabetic patients neurological tests should be used for more accurate results and thus early treatment options to prevent neuropathic complications.
    Full-text · Article · May 2013 · International Journal of Endocrinology
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    ABSTRACT: Due to the absence of myelin in retinal neurons, they represent a good structure to exhibit axonal degeneration in multiple sclerosis. Optical coherence tomography is a relatively new technique that shows axonal damage by measuring the retinal nerve fibre layer. The aim of this study is to investigate whether there is a relationship between OCT and visually evoked potentials and disability related to the disease in patients with multiple sclerosis. The study included 30 patients diagnosed as relapsing remitting multiple sclerosis, 10 as secondary progressive multiple sclerosis, and 20 control subjects. The P100 wave was obtained with pattern visually evoked potential. Optical coherence tomography was used to measure the retinal nerve fibre layer thickness. The findings were compared with Expanded Disability Status Scale scores in the patient groups. The secondary progressive group had thinner nerve fibre layer than the controls (P < 0.001). In both patient groups, P100 wave latency was more prolonged than the controls and this result was statistically significant (P < 0.001). In the secondary progressive group, the reduction in visually evoked potential amplitude was also significant (P < 0.001). No relationship between the disability of either multiple sclerosis group and optical coherence tomograpy and visually evoked potential findings was found (P > 0.05). Read More: http://informahealthcare.com/doi/abs/10.3109/01658107.2012.719260
    Full-text · Article · Oct 2012
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    ABSTRACT: Due to the absence of myelin in retinal neurons, they represent a good structure to exhibit axonal degeneration in multiple sclerosis. Optical coherence tomography is a relatively new technique that shows axonal damage by measuring the retinal nerve fibre layer. The aim of this study is to investigate whether there is a relationship between OCT and visually evoked potentials and disability related to the disease in patients with multiple sclerosis. The study included 30 patients diagnosed as relapsing remitting multiple sclerosis, 10 as secondary progressive multiple sclerosis, and 20 control subjects. The P100 wave was obtained with pattern visually evoked potential. Optical coherence tomography was used to measure the retinal nerve fibre layer thickness. The findings were compared with Expanded Disability Status Scale scores in the patient groups. The secondary progressive group had thinner nerve fibre layer than the controls (P < 0.001). In both patient groups, P100 wave latency was more prolonged than the controls and this result was statistically significant (P < 0.001). In the secondary progressive group, the reduction in visually evoked potential amplitude was also significant (P < 0.001). No relationship between the disability of either multiple sclerosis group and optical coherence tomograpy and visually evoked potential findings was found (P > 0.05).
    Full-text · Article · Sep 2012 · Neuro-Ophthalmology
  • Gulizar Madenci · Sule Bilen · Berna Arli · Mustafa Saka · Fikri Ak
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    ABSTRACT: We aimed to investigate possible associations between systemic iron metabolism deficiency and Parkinson's disease, and also to research any possible correlations between stage of the disease and vitamin B12 and folic acid levels. 33 male and 27 female patients diagnosed with idiopathic Parkinson's disease and 22 male and 20 female age- and sex-matched controls were enrolled in the study. Having the diagnosis of secondary Parkinsonism or Parkinson plus syndromes, and for the females, not being in the menopausal stage were considered as exclusion criteria. Recordings of blood samples of both groups collected after 8 h fasts were assessed in terms of serum iron, ferritin levels and iron-binding capacity, vitamin B12 and folic acid levels. The Hoehn and Yahr scale was used to determine the stage of the disease. No statistically significant difference was found with respect to mean serum iron, median serum ferritin levels and median serum iron-binding capacity between the groups. A statistically significant but inverse correlation was found between symptoms' duration and serum iron and ferritin levels. There was no statistically significant difference between the groups with respect to vitamin B12 and folic acid levels. However, a statistically significant but inverse correlation was determined between the patients' vitamin B12 levels and the Hoehn and Yahr scores. As Parkinson's disease progresses, serum iron, ferritin and vitamin B12 levels may decrease. The lower levels of these parameters may be the cause of the progression or may be the result of it.
    No preview · Article · Feb 2012 · Neurochemical Research
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    ABSTRACT: To determine the nutritional status and anthropometric measurements of patients with multiple sclerosis (MS). This research was conducted on 37 (15 men, 22 women) new diagnosed MS patients who applied to Ankara Numune Education and Research Hospital, Ankara Turkey, from June to August 2011. The nutritional status of patients was determined by a 3-day and 24-hour dietary record and a food frequency questionnaire. Body composition was analyzed by bioelectrical impedance analyzer, and body mass index was calculated. The Nutrient Data Base (BEBIS) program was used to evaluate the energy and nutrient intakes of patients and compared with Dietary Reference Intakes recommendations. Blood samples were collected and serum glucose, lipid profiles, total protein, albumin, total calcium, magnesium, vitamin B12, and vitamin D levels were analyzed. Approximately 5.4% of patients were underweight, 54.1% were normal weight, 24.3% were overweight and 16.2% were obese. Daily mean energy intakes were 2730+/-840.97 kcal in men and 1967+/-647.24 kcal in women. The percentage of the carbohydrates was 46.9%, proteins was 14.6%, and fats of the total energy was 38.4%. Approximately 16.7% of the patients' serum vitamin D, and 6.7% of the patients' serum vitamin B12 levels were below than the reference ranges. Multiple sclerosis patients have high body mass index values and poor nutritional status. It was verified that life style modification with adequate and balanced nutritional habits is very important in MS patients.
    Full-text · Article · Feb 2012 · Saudi medical journal
  • M. Bas · P. Turker · E. Koseler · M. Saka
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    ABSTRACT: The purpose of this study was to evaluate knowledge, attitudes, and practices about food safety among adolescents. The questionnaire was designed to obtain information about adolescents knowledge, practices and attitudes about food poisoning, personal hygiene, cross-contamination and, temperature control. This questionnaire was administered 2074 randomly selected adolescents from Turkey. Most of adolescents answered items about temperature control, cooling and thawing practices wrongly. Most adolescents considered as informed about food safety (76.0%). About, 8.0% of adolescents have experienced foodborne illnesses in the last year. The food safety knowledge of adolescents were positively correlated with food safety attitudes, education level of participants, education level of mother, education level of father and age (p<0.01). Food safety knowledge and attitudes scores of adolescents was 37.8±16.4 (100 possible points) and 62.2±22.7 (100 possible points), respectively. Results also indicated that the mean food safety knowledge and attitude scores were poor among adolescents. As a conclusion, the findings of this study demonstrated that adolescents have lack of food safety knowledge. Therefore, food safety training should be provided for all adolescents in schools. A need for relevant and motivating food safety education exists in this group. Although computer programs, internet, television and other mass media have wider reach, government publications of food safety at home are more trusted, hence, can be used more effectively in educating consumers.
    No preview · Article · Jan 2012 · Healthmed
  • G. Kiziltan · M. Saka · P. Turker · A. Ercan
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    ABSTRACT: Aim: To evaluate the dietary and other factors on the risk of hyperemesis gravidarum (HG) during pregnancy. Method: A case-control study was conducted on thirty women with hyperemesis gravidarum and 30 women without hyperemesis gravidarum admitted to Women Health Care Clinic in Ankara over 3-months period. Dietary (total energy, total fat, saturated fat, monounsaturated fat and polyunsaturated fat intakes) and non-dietary (prepregnancy body mass index, previous history of HG, parity, gravidity, education level, employment and smoking status) factors were evaluated on the risk of hyperemesis gravidarum (HG). Results: Cases and controls were similar with respect to education levels, employment status, gravidity number and smoking habits. Frequency of previous history of hyperemesis gravidarum was significantly higher in women with HG than the women without HG (p<0.05). The odds ratio for the women with hyperemesis history was 0.7 (95 % CI 0.6, 0.9). There were no statistically significant associations with energy (OR = 2.0; 95% CI 0.7,5.9), total fat (OR = 1.2; 95% CI 0.4, 3.3) and saturated fat (OR = 2.0; 95% CI 0.7,5.9) intakes and HG. Conclusion: Despite, previous history of hyperemesis gravidarum had a significant effect on the risk of HG, the etiology of the HG in pregnancy is still unclear because, hyperemesis gravidarum most probably is a disease with a complicated etiology, with several independent and interdependent risk factors.
    No preview · Article · Jan 2012 · Healthmed
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    ABSTRACT: The purpose of this study was to determine the prevalence of night eating syndrome and binge eating disorder in sample of adolescents and also to compare the food craving and eating disorder groups. A total of 563 adolescent male and female high school students (mean age: 16.7±1.3 years for males and 16.6±0.6 years) were randomly selected in Ankara, capital city of Turkey. The participants were administered the Dutch Eating Behaviour Questionnaire, the Weight and Lifestyle Inventory, the Questionnaire on Eating and Weight Patterns -Revised and the Food Craving Questionnaire- Trait. Fourteen female participants (3.7%) reported NES, while 4.5% reported binge-eating symptomatology. Ten male participants (5.5%) reported NES, while 2.7% reported binge-eating symptomatology. Of those reporting the latter, 7 met criteria for purging bulimia nervosa (1.6% of females and 0.5% of males) and 11 met criteria for nonpurging bulimia nervosa (2.6% of females and 0.5% of males). Seven participants reported both night eating and binge eating. As predicted, participants who reported night eating syndrome and binge eating disorder had significantly higher total food craving scores, restrained eating, emotional eating and external eating scores than those not reporting disordered eating. The current study suggests that binge eating disorder and night eating syndrome are strongly significant problem among adolescents. Our findings indicated that the experience of food craving is an important factor in adolescents with binge eating disorder and night eating syndrome. Finally, these eating problems may contribute to the development and/or maintenance of obesity.
    No preview · Article · Jan 2012 · Healthmed
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    ABSTRACT: The purpose of this study was to determine the association between body mass index, depression, emotional, external and restrained eating behavior in adolescent females. The present study examined the relations between body mass index, emotional eating, restrained eating, external eating and depression level in female adolescents. The participants were 644 females aged between 16 and 18 years (mean age 16.71, standard deviation 0.73 years), from one of several randomly selected universities in Ankara, capital city of Turkey The participants were administered the Dutch Eating Behaviour Questionnaire and Beck Depression Inventory. Restrained eating (r=0.32;p<0.05), emotional eating (r=0.37;p<0.05), depression level (r=0.36;p<0.05) and age (r=0.16;p<0.05) all showed significant correlations with BMI, but external eating (r=0.05;p>0.05) was not significantly correlated with BMI. Also, there were significantly differences in body mass index, restrained eating, emotional eating, external eating, depression level and age between the normal weight group and the overweight group. Three factors were found as significantly associated with body mass index. Emotional eating stood out as the major risk factor for body mass index in female adolescents. Second and third important factors are found as restrained eating and depression level. In conclusion, obesity in adolescence might be relationship between emotional eating, restrained eating and depression level among female adolescents. Emotional eating appear to be a major contributor to obesity in the adolescent group in this sample. At this point we can recommend developing interventions for obesity prevention and treatment targeted at emotional eating.
    No preview · Article · Jan 2012 · Healthmed
  • Sule Bilen · H Nalan Güneş · Mustafa Saka · Fikri Ak

    No preview · Article · Jan 2009 · European Journal of Internal Medicine
  • S Bilen · M Saka · F Ak · N Oztekin
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    ABSTRACT: Serotonin-selective re-uptake inhibitors are prescribed widely because they are regarded as having less severe side-effects compared with tricyclics and monoamine oxidase inhibitors. With this popularity, increasing attention has been drawn to their adverse effects. Development of extrapyramidal symptoms has been reported in some patients while taking fluoxetine, a commonly used serotonin-selective re-uptake inhibitor. Here, we report a case of persistent dystonia, thought to be associated with short-term fluoxetine use, which required treatment with botulinum toxin type A.
    No preview · Article · Sep 2008 · Internal Medicine Journal

  • No preview · Article · Dec 2007 · Parkinsonism & Related Disorders

  • No preview · Article · Jan 2007 · Parkinsonism & Related Disorders