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ABSTRACT: Pancreatic schwannoma is a rare tumour. The diagnosis is most of the time hystopathological after the resection of the tumour. The lack of specific symptoms, radiological characteristics from other pancreatic lesions and tumoral markers, makes the preoperative diagnosis challenging. Furthermore, the histological differentiation from the neurofibroma (both tumour originate from the same cellular line) is very important from a surgical and prognostic standpoint. Surgical excision and close radiological follow-up are the key point in the treatment of this tumour. Whenever possible the surgical treatment should aim to the enucleation of the tumour. When this is not possible for anatomical and technical reasons as in our case, more extended resection are justified.