Yousaf Kamal's scientific contributionswhile working at Hamdard University Islamabad Campus (Islamabad, Pakistan) and other institutions
Publications (3)
- Abstract: The present study was designed to assess the effect of methanolic (M) extract of Canscora decussata on hematological parameters in alloxan-induced diabetic rabb-its for duration of one month. (M) extract significantly (P<0.001) increase RBCs, PCV, MCV, MCHC, Hb level, total leucocytes count (TLC), neutrophil and platelet count of the treated diabetic rabbits as compared to the diabetic control group. The extract produced no significant change in Eosinophil, Lymphocyte and Monocyte count. The... Show More
- Abstract: The current study was designed to evaluate the hypolipidemic and renoprotective effects of methanolic extract of powdered Canscora decussata whole plant in the diabetic rabbits. Thirty rabbits were divided into five groups having 6 animals each including normal and diabetic controls groups, the remaining groups received methanolic extract in 400 and 600 mg/kg doses and another group got pioglitazone (3 mg/kg) for 30 days. Serum levels of triglycerides, total cholesterol, LDL-cholesterol,... Show More
- Abstract: The antimicrobial and cholinomimetic activities of ethanolic and chloroform extracts of Conyza bonariensis plant were investigated. Antimicrobial evaluation of ethanol extract (EE) and chloroform extract (CE) of Conyza bonariensis against 3 strains of microorganisms, using agar well and agar disc diffusion method, revealed their activities against Staphylococcus aureus, Escherichia coli and Sarcina lutea (zone of inhibition: 4-10 mm, 5-16 mm and MIC: 1.33-3 mg/mL, 0.23-1.01... Show More
Publications citing this author (3)
- Moreover, use of herbal medicines for the treatment of diabetic complications is very important in developing countries where the cost of conventional medicines is a burden to the population. Plants like Canscora decussate, Punica granatum Sesbania sesban have the protective effect against diabetic nephro-pathy (Irshad et al., 2013;Mestry et al., 2016;Pandhare et la., 2011;).Eruca sativa Millis (salad rocket) is a diploid annual herbaceous plant growing up to 80 cm (Hedrick, 1972). Leaves are increasingly eaten by humans either alone or as part of mixed salads, and are also used in herbal remedies (Mahran et al., 1991).
[Show abstract] [Hide abstract] ABSTRACT: p class="Abstract">The present study was aimed to evaluate petroleum ether and hydroalcohol extracts of Eruca sativa seeds in the treatment of diabetic nephropathy in the rat model. GC-MS analysis of petroleum ether extract revealed the presence of fatty acids and erucic acid. Quercetin and kaempferol were isolated from the hydroalcohol extract. Diabetes was induced in rat by streptozotocin (65 mg/kg i.p.) 15 min after nicotinamide (230 mg/kg, i.p.) administration. Both the extracts at different doses produced a significant attenuation in the elevated serum glucose level. Elevated renal parameters, lipid and anti-oxidant enzyme levels were restored in a dose-dependant manner. Moreover, both extracts produced significant reduction in the formation of advanced glycation end products in the kidney. These findings suggest that E. sativa might inhibit the progression of diabetic nephropathy and could be a therapeutic agent for the management of diabetic nephropathy. Video Clip of Methodology : Extraction of compounds from seeds: 3 min 45 sec Full Screen Alternate </p
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