[Show abstract][Hide abstract] ABSTRACT: A new, rapid, and efficient method, multiple reaction monitoring liquid chromatography–tandem mass spectrometry, has been
developed for analysis of nanafrocin in foodstuffs of animal origin. The researchers used a C18 stationary phase coupled with triple-quadrupole tandem mass spectrometry in negative-electrospray mode. The limits of detection
(LOD) and quantification (LOQ) were 0.005 and 0.01mgkg−1, respectively, in the matrixes. Detector response was found to be a linear function of concentration over the range 0.005–0.1mgkg−1 in each matrix. Mean overall recovery (n=10) of nanafrocin varied from 71 to 101%. The results show that identification and quantification of nanafrocin residues
in foodstuffs of animal origin can be successfully achieved by use of the proposed LC–MS–MS method.
KeywordsColumn liquid chromatography–mass spectrometry-Nanafrocin-Veterinary drug
[Show abstract][Hide abstract] ABSTRACT: Chitosan-based silver nanoparticles were synthesized by reducing silver nitrate salts with nontoxic and biodegradable chitosan. The silver nanoparticles thus obtained showed highly potent antibacterial activity toward both Gram-positive and Gram-negative bacteria, comparable with the highly active precursor silver salts. Silver-impregnated chitosan films were formed from the starting materials composed of silver nitrate and chitosan via thermal treatment. Compared with pure chitosan films, chitosan films with silver showed both fast and long-lasting antibacterial effectiveness against Escherichia coli. The silver antibacterial materials prepared in our present system are promising candidates for a wide range of biomedical and general applications.
No preview · Article · Sep 2009 · Carbohydrate research