Iqbal Ahmed Memon

Dow University of Health Sciences, Kurrachee, Sindh, Pakistan

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Publications (18)2.53 Total impact

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    Full-text · Dataset · Jul 2014
  • I.A. Memon · S. Tariq
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    ABSTRACT: Helicobacter Pylori [H.P] infection is a newer infective organism of gastrointestinal system which not only is an asymptomatic infection in children but is now an established cause of peptic ulcer disease as well as a carcinogen. It is now incriminated in many other disorders. The diagnostic modalities have limitations in pediatric age group. Our ever changing world mandates clinicians to be abreast and equipped with information to recognize, evaluate and be able to treat patients effectively. Flexible Endoscopy allows for direct visualization of the mucosa; for the detection of H pylori by means of biopsy, culture, cytological analysis and for DNA testing through PCR. However, issues of availability, acceptance by parents, and cost certainly remain limiting factors. Non invasive modalities are becoming more available, acceptable and affordable. Eradication treatment in children is available with over 90% rate of success. Eradication of HP is recommended for HP positive Peptic Ulcer Disease. Information about pediatric aspects of this infection and disease should increase awareness and appropriate diagnosis and management.
    No preview · Article · Jan 2013
  • I.A. Memon · S. Tariq · A. Jamil
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    ABSTRACT: Objective: The objective of the study was to determine the frequency of malaria in febrile children aged 2 months to 5 years and to document type of plasmodium species in the area. Methodology: Malarial parasite in the thick films and differentiation of the species were sought in the thin slides was done on twelve hundred children coming to the Pediatric Outpatient Department at Civil Hospital Karachi for the evaluation of fever. Data was collected from March 2010 - Febuary 2011. Cinical findings and the type of malarial species was recorded. Results: Out of a total OPD flow of 1200 children coming for evaluation of fever only 5% of febrile children had malaria. P. Falciparum was detected in 85% and P. vivax was seen in 15%. There were associated gastrointestinal symptoms in 18%, respiratory symptoms in 32%, urinary symptoms in 7%, nonspecific symptoms in 32% cases. 53% cases had mixed symptoms. Anemia was present in all cases. More than two thirds children were malnourished while none was having severe malnutrition. Visceromegaly was seen in only 15% of the children (10% having splenomegaly and 5% hepatomegaly). Conclusion: This area falls under the category of "high risk" area for malaria (more than 5% and Plasmodium falciparum is the dominant species fall under). These findings should be confirmed in the light of more broad based studies and continuous monitoring atleast every 5 years is needed in this area.
    No preview · Article · Jan 2012
  • I. Memon · F. Arif · A. Jamal · G. Murtaza · A. Imran · S. Parveen · S. Aslam
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    ABSTRACT: Objective: To determine the status of supplementary Polio doses given on National Immunization days and the status of routine immunization of all cases of Polio in Sindh. Study Design: Descriptive/ Cross-sectional Setting: All the districts of Sindh. Methodology: All polio cases reported confirmed by virus isolation in all the districts of Sindh were evaluated for the status of routine and supplementary immunization. Results: A total of 245 children with confirmed Polio were analysed. In 2000 35.3% children with P1W received no supplementary doses while none received 7+ doses while in 2009 all effected children received supplementary doses with 83.3% receiving 7+ doses with a similar pattern for P3W cases. Routine immunization of these children showed that in 2000, 48.4% of P1W cases had not received any routine polio doses as compared to 2009 where 50% were not immunized. A similar pattern was also seen with P3W cases with 41.2% and 66.7% in 2000 and 2009 respectively who did not receive any routine doses Conclusion: Routine immunization of polio patients is poor.Strengthening of routine immunization is an important step to achieve polio eradication.
    No preview · Article · Jan 2012 · Medical Channel
  • I.A. Memon · M.N. Lal · S. Tariq · Adil
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    ABSTRACT: Purpose: The purpose of this study was to assess the frequency of H. pylori infections in children with upper gastrointestinal complaints. This study was also aimed to evaluate the usefulness of diagnostic methods and to assess the effectiveness of treatment. Study design Cross sectional study: Place & duration of study: Pediatrics unit, Civil Hospital, Karachi for 36 Months, (Aug. 2001 to Jul. 2004). Patients & methods: Upper gastrointestinal endoscopy and gastric mucosal biopsy were performed on 129 children who visited the OPD or were admitted to the Department of Pediatrics Dow University of health sciences & Civil Hospital Karachi or directly referred from other Pediatric facilities of the province from, Aug. 2001 to Jul. 2004 due to abdominal complains or upper gastrointestinal bleeding. All patients who under went upper GI endoscopy examination were analyzed retrospectively from record. Results: Out of 129 biopsies, 70 were positive for H.Pylori culture and histopathological evidence. Conclusions: The prevalence of H. pylori infection in children presenting with abdominal complaints was 54%. These children underwent for upper GI endoscopy who were referred due to abdominal complains. This is a very high rate of infectivity and physicians in general and pediatricians particularly need to keep a high index of suspicion for this organism, so that proper treatment for children with abdominal complaints might lower the incidence of peptic ulcer diseases or gastric cancer with advancing age.
    No preview · Article · Jan 2012 · Medical Channel
  • I.A. Memon · M.N. Lal · S. Tariq · S. Chand · Ainee · Irum · Aysha · Sirichand
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    ABSTRACT: Objective: The Objectives of the study were to observe the different endoscopic findings and to enumerate complications associated with the procedure. Design: Retrospective Cross Sectional study. Place and Duration of Study: The venue of the procedure was Endoscopic unit of Pediatrics Unit of Civil Hospital Karachi from January 1998 till September 2009. Materials & Methods: 991 gross endoscopic findings and biopsies were retrospectively analyzed from record. After taking consent history and examination of all patients were recorded on a performa. Fasting for 4-8 hours depending on age was a prerequisite and other steps were a good Hb level and I/V cannula placement. Results: This was a retrospective study of over 10 years. From January 1998 till September 2009 a total of 991 children who underwent the procedure ranging in age from 4 mnths to 18 years and were referred from other wards of Civil Hospital Karachi, NICH, Lyari General Hospital and charitable hospitals from Lyari catchments area were analyzed. There were different reasons for referral like chronic diarrhea (for jejunal biopsy), abdominal pain, upper GI bleed, Failure to thrive, suspected acid peptic disease, CLD with or without portal hypertension, vomiting, malena, anorexia and dysphagia. Major endoscopically observed findings were gastritis, esophageal varices, GERD, duedenitis etc along with vast majority with normal or subtle findings of smaller duodenal folds and reduced sheen in cases referred for jejunal biopsy for diagnosis of Celiac Disease. It was found to be a much safer procedure than literature suggests. Conclusions: Pediatric GI endoscopy units with independently standing are limited; our endoscopy unit is one of the 3 centers operational in the country. It is an excellent diagnostic and therapeutic tool. Complications are rare in good hands. Availability of this immensely useful diagnostic as well as therapeutic tool is certainly a limiting factor in our setup but when accessible it should be utilized.
    No preview · Article · Jan 2011 · Medical Channel
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    ABSTRACT: Objective: To compare the results of conventional open with laparoscopic cholecystectomy regarding their operative time and postoperative parameters. Methodology: This is a comparative study of 400 patients of cholelithiasis operated for either open or Laparoscopic cholecystectomy during five years from January 2004 to December 2008. The cases were compared for operative time and various postoperative parameters in order to assess the advantages and disadvantages of each procedure. The patients were divided into two groups, group OC for open and group LC for laparoscopic cholecystectomy, each comprising of 200 cases. Results: The operative time was longer in OC than LC patients with mean operative time of 54.16± 11.94 minutes in OC and 46.89±14.83 minutes in LC group (P<0.001). The overall frequency of postoperative complications was relatively high in OC group 50.5% as compared to LC (37%) including all minor and major problems with combined morbidity of 43.75% (P<0.001). The mean hospital stay was shorter in LC group as compared to OC group i.e. 3.02±1.75 (range 1-5) days versus 5.56±9.8 (range 4-10) days respectively. Return to normal work was also significantly shorter in LC group i.e. 18.06±5.16 days (range 1-4 weeks) as compared to 31.61±7.6 days (range 3-6 weeks) in OC group with p value <0.001. Conclusions: The laparoscopic cholecystectomy is superior to open cholecystectomy due to short operative time, early mobilization and fast recovery, less postoperative pain and complications, short hospital stay and early return to work. Comparative study of conventional open versus laparoscopic cholecystectomy for symptomatic cholelithiasis. Pak J Med Sci 2011;27(1):33-37 1.
    Full-text · Article · Jan 2011
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    ABSTRACT: To analyze the frequency and causes of anaemia in systemic lupus erythematosus (SLE) patients attending in department of medicine at tertiary care hospitals. This retrospective, descriptive and analytical study was planned to analyze the frequency and causes of anaemia in SLE patients attending the department of medicine at (MMC) and (LUMHS) hospitals during the period of Jan 2006 to Nov 2008. The criteria used in this study were from the American College of Rheumatology. Investigations recorded were blood complete picture, absolute values, peripheral smear, and reticulocyte count in all patients of anaemia. These investigations were necessary to analyse the cases of anaemia in SLE. All investigations were not done in all cases. Patients with hypochromic microcytic anaemia were advised to have serum iron and ferritin levels, seven patients with macrocytic anaemia were advised to have direct and indirect coomb's test, LFTs, serum LDH, serum B12 and folate levels. Patients with normochromic and normocytic anaemia were considered to have anaemia of chronic disease. Bone marrow aspiration and Hb electrophoresis were done in two patients with anaemia of chronic disease. Thirty adult patients were included in this study. Special proforma were prepared to record the information from case sheets of patients including basic information, symptomatology and laboratory investigations. Severity and various types of anaemias were recorded. Anaemia was graded according to severity, as mild (Hb 10-12 G/dl), Moderate (Hb 8-10 G/dl) and severe (Hb < 8 G/dl). Haemoglobinopathies and other types of anaemias were excluded from study. Thirty adult diagnosed patients of SLE, were included. Their ages ranged from twenty years to fifty years at time of presentation. The mean age +/- SD (range) was 28 +/- 6.22 (20-50) years and median age was 31 years. Out of thirty patients, twenty seven (90%) were females and three (10%) were males. Twenty eight (93.33%) patients presented with anaemia, 14 (46.66%) patients were of mild anaemia, 8 (26.66%) patients were of moderate grade anaemia and 6 (20%) patients had severe anaemia. Iron deficiency anaemia was found in 9 (30%) patients, 12 (40%) patients had anaemia of chronic disease and 7 (23.33%) patients had haemolytic anaemia, out of theses 7 patients, 5 (16.66%) patients had Coomb's positive haemolytic anaemia. All thirty patients had ANA positive titres > 1:80; and nineteen (63.33%) patients had anti ds DNA positive, titres > 1:10. Haematologic abnormalities are common manifestations in patients with SLE. Most patients exhibit anaemia at some point during their disease course.
    No preview · Article · Oct 2010 · Journal of the Pakistan Medical Association
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    ABSTRACT: Various autoimmune diseases have association with each other but it is very rare to see multiple autoimmune diseases in one patient. Presence of more than two autoimmune diseases in one patient is known as multiple autoimmune syndrome (MAS). We report the case of an 11 years old girl who presented with history of swelling in front of the neck along with constipation, anorexia, weight gain and increasing pallor over a period of six months. Additionally she had an episodic history of joint pains and abdominal pain with no specific relation to diet, time, other gastrointestinal or genitourinary symptom. Hypothyroid goiter (Autoimmune thyroiditis, Hashimoto's thyroidits) was diagnosed by raised thyroid stimulating hormone (TSH), low T4 and presence of thyroid specific antibodies in blood. Patient was discharged on tablet Levothyroxine to which she responded well with reduction in size of the swelling and relief of the symptoms except for the joint pains and abdominal pain. To evaluate the persistent symptoms she was investigated further for other autoimmune diseases and was diagnosed to be having systemic lupus erythematosus (SLE) and Coeliac disease also. The final diagnosis was multiple autoimmune syndrome (Hashimoto's thyroiditis, Coeliac disease and SLE).
    Preview · Article · Oct 2010 · Journal of the Pakistan Medical Association
  • Latif S · Jamal A · Memon I · Yasmeen S · Tresa V · Shaikh AS

    No preview · Article · Jan 2010 · Journal of the Pakistan Medical Association
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    ABSTRACT: To assess serum zinc and magnesium level in type-2 diabetic patients and the effect of age, gender, glycemic control and duration of diabetes on these trace elements in comparison with those of control subjects. Non-interventional case control study. Department of Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad, from October 2007 to March 2008. There were 42 diabetic patients and 42 age matched non-diabetic (control) subjects included in this study. Serum zinc, serum magnesium and fasting blood sugar measured among the diabetic and control groups and association of both trace elements were assessed with glycemic status, age, gender and duration of diabetes using SPSS version 16.0 for analysis. Serum zinc level was significantly lower (mean 2.03 +/- 0.39 mg/dL) in diabetic patients as compared to control subjects (4.84 +/- 4.217 mg/dL, p = < 0.001). No significant difference was found in serum magnesium level with mean of 22.67 +/- 24.5 mg/dL in diabetic patients as compared to controls (18.3 +/- 3.4 mg/dL, p = 0.26). Serum zinc level was significantly lower in type-2 diabetics, whereas no significant difference was found in serum magnesium level when compared with control subjects. There was no association of age, gender, glycemic status and duration of diabetes on the serum concentration of these trace elements in type-2 diabetic patients.
    Full-text · Article · Sep 2009 · Journal of the College of Physicians and Surgeons--Pakistan: JCPSP
  • Iqbal Ahmed Memon · Ammarah Jamal · Hamida Memon · Naila Parveen
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    ABSTRACT: To determine the frequency and clinical presentation of amoebic diarrhea in children and its effect on the nutritional status of the affected children. Descriptive. Department of Diarrhea Treatment Unit (DTU), Dow Medical College and Civil Hospital, Karachi, from November 1998 to April 2001. Paediatric patients between the ages of > 1 month to 15 years were included, who visited the DTU of the department with diarrhea. Stool samples of all these patients were checked under microscope for the vegetative forms of Entamoeba Histolytica (E.H.). Patients who were positive for E.H. were evaluated for the symtomatology including the type of diarrhea {acute watery diarrhea (AWD) or dysentery}, abdominal pain, tenesmus and nausea/vomiting. Examination carried out was assessed for state of hydration, fever and anaemia and nutritional status of those less than 5 years of age. The patients were divided into three age groups to assess the association of the age with severity and type of clinical presentation. Chi- square test was applied to calculate the p-values. P-values of 0.05 or less were considered statistically significant. The stool samples of 3870 patients with diarrhea were examined under microscope. Three hundred and twenty eight (8.47%) of these samples were positive for E.H. The difference between the number of patients presenting with acute watery diarrhea n=157, 47.86% and with dysentery n=171, 52.13% was found to be statistically non-significant (p=0.364). Two hundred and seventy seven (84.45%) patients had tenesmus, while abdominal pain was present in 287 (87.5%). Fever and malnutrition were present in 169 (51.52%) patients each. Malnutrition was significantly most frequent in 1-5 years of age groups (n=98, 57.98%, p=0.026). The nutritional evaluation of the 272 under-5 children with amoebic diarrhea showed a significantly normal status in 123 (45.55%, p-value < 0.001). All the signs and symptoms followed a similar trend with 1-5 years age group being the most affected group. However, the frequency of blood in stools increased in direct proportion to the increasing age. Although dysentery was the more common presenting complaint, almost half of the patients presented with watery diarrhea. Most of the patients with dysentery were under the age of 5 years. Fever was present in a high number of patients. The age group most affected by amoebiasis and malnutrition was 1-5 years.
    No preview · Article · Aug 2009 · Journal of the College of Physicians and Surgeons--Pakistan: JCPSP
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    Ghulam Murtaza · Iqbal Ahmed Memon · Abdul Rauf Memon · MN Lal · Nawaz Ali Kallar
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    ABSTRACT: Objective: To determine the prevalence of Malarial parasites and species responsible in Sindh Province of Pakistan. Methodology: It is a cross sectional descriptive study conducted in all Districts of Sindh during January 2002 to December 2006. It was based on surveillance data of Malaria control program Sindh in which blood smears from febrile cases in all age group of male and female were seen by facility microscopist in all districts. Senior microscopist rechecked all positive slides. All slides data of different districts of Sindh was reported on monthly basis to provisional centre at Hyderabad for compiling and analysis. Results: During 2002-2006, out of 5.84 million slides, those with positive malarial parasites were approx. 0.16 million giving an average blood examination rate (BER) 4.46, slide positivity rate (SPR) 2.94, Falciparum ratio(FR) was 41%, annual parasite incidences (API) was 1.36. More cases were seen in post monsoon season. Conclusion: All basic indicators of Malaria disease are higher than optimum level. Estimated burden can be much higher, Roll Back Malaria goals are lagging far behind to reduce the disease burden. As such integrated approach of diagnosis, treatment and prevention is required.
    Preview · Article · Jul 2009 · Pakistan Journal of Medical Sciences Online
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    ABSTRACT: The objective of this study was to assess the frequency of thyroid dysfunction in response to combination of interferon and ribavirin therapy in chronic hepatitis C (CHC) patients and HCV outcome. Descriptive study. Place and Duration of Study: This study was conducted at Outpatient Department of Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad from September 2005 to September 2007. One hundred cases of CHC, proven by anti-HCV and HCV RNA-positive with baseline TSH, FT4 and FT3 within the normal reference range, who were treated with interferon alpha-2b (3 million unit subcutaneously three times per week) and oral ribavirin (1000-1200 mg per day) were included in this study. All patients were assessed for TSH, FT4, FT3 levels at 12 weeks and 24 weeks during therapy. Among the 100 patients, overt thyroid disease developed in 13 (13%) and sub-clinical thyroid disease in 5 (5%). Out of 13 patients of overt thyroid disorders, 11 (84.6%) had hypothyroidism and 02 (15.3%) hyperthyroidism. Four (80%) patients were of sub-clinical hypothyroidism and 01 (20%) patient was of sub-clinical hyperthyroidism. Overall, thyroid disorders developed in 18 (18%) both as overt and sub-clinical thyroid disorders. Ninety one (91%) patients became negative by HCV RNA. Treatment of HCV with IFN-alpha and ribavirin can be safely continued in patients with over and sub clinical hypothyroidism because thyroid disease responds well to treatment.
    No preview · Article · Jul 2008 · Journal of the College of Physicians and Surgeons--Pakistan: JCPSP
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    Preview · Article · Jan 2007
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    ABSTRACT: Objective: To evaluate freguency of acute pancreatits in pregnancy and its associated maternal and foetal complications. Study Design: Case Series. Setting & Duration: Department of Surgery, Unit III, Civil Hospital, Karachi from June 2001 to January 2008. Methodology: All pregnant females referred with suspicion of acute pancreatits were included and were further reviewed for maternal and foetal outcomes. Result: The frequency of acute pancreatits in pregnancy was 7.83%, the most commonly presenting symptom was epigastric pain and tenderness while biliary pancreatits was the most common aetiology seen in 61.53% of cases. The recurrence rate during the same pregnancy was 15.38% while the total number of maternal deaths were 4(30.76%) and 9(69.23%) patients suffered severe morbidities. A total of 6(46.15%) fetuses suffered morbidities while their were six (46.15%) mortalities. Conclusion: Acute pancreatits in pregnancy though a rare but a dreaded conditon. The associated maternal and foetal complications can be reduced by early diagnosis and thus early referral for apprprite specialist care.
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    Muhammad Ayub · Rauf Sheikh · Shoaib Gangat · Anjum Rehman · Iqbal Ahmed Memon
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    ABSTRACT: Objective: To evaluate the safety of single layer interrupted extra mucosal intestinal anastomosis in comparison with the double layer conventional methods of intestinal anastomosis. Methodology: All patients requiring intestinal anastomosis were included. They were divided into two groups. In-group A single layer interrupted extra mucosal anastomosis was done with 2/0 vicryl while in-group B conventional double-layered anastomosis with 2/0 vicryl was made. Outcome of the two techniques in terms of morbidity, mortality and cost effectivity was compared. Results: Ninety patients were included in our study (42 in group A and 48 in group B). Mean age for group A was 37.5years and group B 40.2 years respectively. Entero-enterostomy, entero-colostomy and colo-colostomy were done in 30(71.4%), 10(23.8%) and 2(4.7%) patients in-group A and 35(72.9%), 10(20.8%) and 3(6.3%) patients in group B respectively. Two patients (4.7%) in group A and four patients (8.3%) among group B developed anastomotic leakage with overall mortality 0% in group A and 4.1% in group B. Conclusion: A single layer interrupted extra mucosal intestinal anastomosis can be constructed in less time with minimal complication compared with two-layered technique. It can be safely introduced into surgical training programme. Volume 25, Issue 3, 2009 is internationally accepted. 3 The objections against double layered anastomosis is that in most of the cases it fails to oppose clean serosal surfaces and it results in large amount of ischemic tissue within suture line which increases the chances of leakage. Further excessive inversion leads to narrowing of lumen. 4 In contrast single layer anastomosis causes least damage to sub mucosal vascular plexus least chances of narrowing of lumen, incorporates strongest sub mucosal layer and accurate tissue apposition. 5 this prospective comparative study was performed to evaluate the safety of single layer interrupted extra mucosal technique.
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    Anjum Rehman · Shoaib Gangat · Muhammad Ayub · Sehar Fatima · Iqbal Ahmed Memon
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    ABSTRACT: Objective: To study the frequency of breast carcinoma in pregnancy and its outcome in our population. Design: Case series. Setting & Duration: Surgical Unit III, Civil Hospital Karachi from January 2001 to September 2007. Patients: All the patients of proven pregnancy associated Breast cancer were included Methodology: All those patients with pregnancy associated breast cancer proven by histology admitted either through OPD or referred from Gynaecology Department were evaluated. Results: During the study period total number of patients were eight (10.9%) out of 73 total cases of breast carcinoma. Five (62.5%) were under the age of forty years while mean age of menarche was 13.4 years. Three (38%) had parity of four, while almost all of them six (75%) breast fed their babies. Maximum number of patients, three (38%) presented in second trimester, four (50%) were in Stage III when diagnosed as a case of PABC. During the study period four (50%) ended up in termination of pregnancy and 38% of females died during different stages of treatment. Conclusion: Breast Cancer which is the most common malignant condition in pregnent women has through still at a low incidence but is apparently on the rise due to advance age at first pregnancy as well as physiological changes in pregnancy masked features of malignancy necessitate thorough examination and evaluation of breast in early pregnancy. Volume 24, Issue 3, 2008 thrice to those who conceive in late teens. 3 With the tendency to prefer late age pregnancy, the incidence is also on the rise. Micro anatomical and endocrinogical changes occuring in the breast during pregnancy render it more difficult to examine and interpret its examination findings thus making the diagnosis all the more difficult. 4 Scarff Bloom, Richardson grade of Pregnancy associated breast carcinoma appears to be higher than in non-preg-nant patients. 5 For the same reason Mammography and Fine Needle Aspiration Cytology (FNAC) are of limited value in diagnosis during pregnancy and inversely biopsy is of greater value. 6 There is hardly any role of radiotherapy of breast cancer during pregnancy though there are some who advocate chemotherapy in least stages. Modified Radical Mastectomy is the best option. 7 The purpose of this study was to evaluate the frequency of breast carcinoma in pregnancy and its outcome in our population.
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Publication Stats

53 Citations
2.53 Total Impact Points

Institutions

  • 2009-2010
    • Dow University of Health Sciences
      Kurrachee, Sindh, Pakistan
    • Civil Hospital Karachi
      Kurrachee, Sindh, Pakistan
  • 2008-2009
    • Liaquat University of Medical and Health Sciences
      • Department of Medicine
      Jamsboro, Sindh, Pakistan