Hiroshi Nakatani

Keio University, Edo, Tōkyō, Japan

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Publications (1)0.9 Total impact

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    Yoshinaga Kawano · Junichiro Irie · Hiroshi Nakatani · Satoru Yamada
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    ABSTRACT: Although recent studies recommended that insulin should be administered to patients with slowly progressive type 1 diabetes, even those with non-insulin dependent status, patients prefer oral hypoglycemic agents to insulin injections. We report a slowly progressive type 1 diabetic patient whose insulin production was preserved for 4 years (SigmaC-peptide from 29.48 ng/mL to 24.58 ng/mL) using pioglitazone despite a high titer of anti-GAD antibody (GADA; 120.7 U/mL). This case suggests that pioglitazone might prevent or delay the loss of insulin secretion and insulin dependency in slowly progressive type 1 diabetic patients.
    Full-text · Article · Feb 2009 · Internal Medicine