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Publications (5)

  • [Show abstract] [Hide abstract] ABSTRACT: BACKGROUND: The calcium is not absorbed in the lack of hydrochloric acid and the osteomalacia and osteoporosis may occurs; it is well recognized in patients that had gastric resection. AIM: To evaluate the effects of the partial gastrectomy associated to anterior truncal vagotomy in the absorption and metabolism of calcium. METHODS: Eighteen adults male Wistar rats were submitted to partial gastrectomy associated to anterior truncal vagotomy (GXT, eight animals) and the sham operation (10 animals, control group). The diet consumption and the weight gains of the animals were measured three times during the week. The animals received formulated experimental diet orally (AIN-93M) by eight weeks. The serum calcium, urinary and fecal calcium, apparent absorption of the calcium, activity of the enzyme alkaline fosfatase and calcium in the bone were measured after 60 days. RESULTS: The sham operated animals showed higher diet consumption, weight gains, serum and urinary calcium, excretion of calcium in feces, apparent absorption of calcium and activity of the enzyme alkaline fosfatase (P<0,05) as compared to the animals of the gastrectomized group. However, the concentration of the bone calcium was increased in the animals of the gastrectomized group. CONCLUSION: Partial gastrectomy associated to anterior truncal vagotomy showed to be a good experimental model the study calcium metabolism, decreasing the calcium absorption, serum and urinary calcium and activity of the enzyme alkaline fosfatase. However, for alterations at bone level in rats suggests an experimental study in larger period.
    Article · Jun 2009 · Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery
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    [Show abstract] [Hide abstract] ABSTRACT: The aim of the study is to evaluate cervical esophagogastric anastomosis complications between mechanical device versus manual suture. Thirty patients with megaesophagus with grade III/IV submitted to the esophagectomy transmediastinal approach were reviewed with average age from 31 to 68 years. The reconstruction was performed by gastric transposition and with anastomosis in the cervical region. The patients were divided in two groups: A) 15 patients had mechanical suture with the DHC 29 mm device, and B) 15 patients had manual suture in two layers. Five patients (16.6%) presented pneumonia, and they were managed clinically. Three patients were in group B and two were in group A, and no statistical significance was found. Six patients (20%) presented leakage at the cervical esophagogastric anastomosis; one in group A (6.6%) and five in group B (33.3%), with no statistical significance. Anastomosis leakage with development of stricture occurred in five patients in group B, and in three in group A, as well in other two without leakage complications. All of them were managed successfully with endoscopic dilatation. Statistical evaluation was not significant for this complication between group B (33.3%) and group A (20%). There were no deaths in this study. This study showed that mechanical suture is as adequate as manual suture by presenting anastomosis leakage incidence smaller, however, with no statistical significance, and with similar stricture incidence.
    Full-text Article · Feb 2009 · Revista do Colégio Brasileiro de Cirurgiões
  • [Show abstract] [Hide abstract] ABSTRACT: OBJETIVO: Avaliar as complicações da anastomose esofagogástrica cervical com sutura mecânica e manual. MÉTODOS: Foram estudados 30 pacientes com megaesôfago do grau III/IV submetidos a esofagectomia transmediastinal, com idade variável de 31 a 68 anos. A reconstrução do trânsito foi realizada pela transposição gástrica e com anastomose na região cervical, sendo os pacientes divididos em dois grupos: A) 15 pacientes - Sutura mecânica com o aparelho DHC 29 mm e B) 15 pacientes - Sutura manual em dois planos. RESULTADOS: Cinco pacientes (16,6%) apresentaram complicações clínicas conseqüentes à pneumonia com boa evolução clínica, sendo três pacientes do Grupo B e dois do A, sem significância estatística. Seis pacientes (20%) apresentavam deiscência da anastomose esofagogástrica cervical, sendo um (6,6%) do Grupo A e cinco (33,3%) do Grupo B, não sendo significante a diferença entre os grupos. Os cinco pacientes do Grupo B que apresentaram fístula da anastomose esofagogástrica cervical e três do Grupo A, um com fístula da anastomose e outros dois sem esta complicação, evoluíram com estenose da anastomose, sendo tratado com sucesso com dilatações endoscópicas. A avaliação estatística não evidenciou significância dessas complicações em relação aos grupos (A - 20%; B - 33,3%). Nenhum paciente evoluiu a óbito. CONCLUSÃO: Os resultados deste estudo demonstraram que a sutura mecânica é adequada por apresentar menor índice de deiscência da anastomose que a manual, mas sem significância, e com índice de estenose semelhante.OBJECTIVES: The aim of the study is to evaluate cervical esophagogastric anastomosis complications between mechanical device versus manual suture. METHOD: Thirty patients with megaesophagus with grade III/IV submitted to the esophagectomy transmediastinal approach were reviewed with average age from 31 to 68 years. The reconstruction was performed by gastric transposition and with anastomosis in the cervical region. The patients were divided in two groups: A) 15 patients had mechanical suture with the DHC 29 mm device, and B) 15 patients had manual suture in two layers. RESULTS: Five patients (16.6%) presented pneumonia, and they were managed clinically. Three patients were in group B and two were in group A, and no statistical significance was found. Six patients (20%) presented leakage at the cervical esophagogastric anastomosis; one in group A (6.6%) and five in group B (33.3%), with no statistical significance. Anastomosis leakage with development of stricture occurred in five patients in group B, and in three in group A, as well in other two without leakage complications. All of them were managed successfully with endoscopic dilatation. Statistical evaluation was not significant for this complication between group B (33.3%) and group A (20%). There were no deaths in this study. CONCLUSION: This study showed that mechanical suture is as adequate as manual suture by presenting anastomosis leakage incidence smaller, however, with no statistical significance, and with similar stricture incidence.
    Article · Feb 2009 · Revista do Colégio Brasileiro de Cirurgiões
  • [Show abstract] [Hide abstract] ABSTRACT: To evaluate the effects of the partial gastrectomy associated to anterior truncal vagotomy in the absorption and metabolism of iron. Eighteen adults male Wistar rats were submitted to the partial gastrectomy associated to anterior truncal vagotomy (eight animals) and the sham operation (10 animals, control group). The diet consumption and the weight gains of the animals were monitored three times during the week. The animals received supplements of vitamin B12, for the prevention of the megaloblastic anemia, and a formulated experimental diet orally and denominated AIN-93M by 8 weeks. The fecal iron, apparent absorption of the iron, haematocrit, haemoglobin and serum iron were measured after 60 days. The animals undergoing sham operation presented larger statistical averages (p<0.05) for the diet consumption, weight gains, apparent absorption of iron, haematocrit, haemoglobin and serum iron compared to the gastrectomized group. However, the excretion of iron in feces was larger in the gastrectomized group (+14.3%) (p<0.05) when compared to the control group. Partial gastrectomy associated to anterior truncal vagotomy showed to be a good experimental model the study of iron metabolism, decreasing the haematocrit, the haemoglobin and the iron absorption, consequently causing anemia.
    Article · Nov 2008 · Acta cirurgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia
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