Publications (5)2.79 Total impact
- [Show abstract] [Hide abstract] ABSTRACT: Implantology has been an important component of dental management for over forty years, and during that period, many configurations of implant materials and methods have been developed. As empirical and clinical research yield new implant materials, there has been need to test and compare these materials to provide the most cost-effective and efficient implants. Evaluation of efficiency of implants has relied heavily on histological and radiological methods, but these one-dimensional measurement methods fail to evaluate the osteoblastic activity and osseointegration properties of putative implants. In this report, we describe the use of a quantitative single photon emission computed tomography (SPECT) as a tool for comparing the osseointegrating capabilities of two types of implants.
- [Show abstract] [Hide abstract] ABSTRACT: The study was designed to exploit the single photon emission computerized tomography (SPECT) to compare osteoblastic activity of two implant systems: an Endopore implant (Beaded implants) placed immediately into an extraction socket in conjunction with peri-implant autogenous grafting supplemented with a guided tissue regeneration (GTR) technique, and an Endopore implant placed immediately into the extraction socket without peri-implant grafting and GTR. Endopore implants of the same size (12 mm x 4.1 mm INT-Hex) were placed in fresh extraction sockets in the canine-tooth region of the pigs jaw. The implant on the right side had peri-implant bone grafting utilizing autogenous bone together with cytoplast resorbable GTR membrane, whilst the implant on the left side received no peri-implant bone grafting. Osteoblastic activity was evaluated 81 days (11 weeks and 4 days) post implantation using the SPECT imaging technique. The SPECT imaging revealed more osteoblastic activity on the side with peri-implant bone grafting as compared with the site without peri-implant bone grafting. The result suggests that peri-implant bone grafting with GTR around the immediate implant showed more osteoblastic activity and thus enhanced osseointegration when compared with the implant without bone grafting and GTR. Bone grafting and GTR should be encouraged as a standard procedure with dental implants.
- [Show abstract] [Hide abstract] ABSTRACT: To utilize single photon emission computerized tomography performed in sequence to determine the osseo-integrating capabilities and osteoblastic activities of a new bone regeneration technique called the membrane--sandwich technique (Ogunsalu sandwich bone regenerating technique) and to compare the quality and quantity of bone formed by this bone regeneration unit to bone regeneration obtained by using the same particulate bone grafting material covered with interceed (another type of bio-resorbable membrane). Single photon emission computerized tomography bone imaging was performed in sequence on the mandible of a total of 6 pigs on both the right and left side (total of 12 sites) at two and a half hours following the injection of technetium 99m methylene diphosphate. Imaging was performed using a Siemen Orbitar II gamma camera. The projection data was acquired in a 128 x 128 matrix over 180 arc and SPECT reconstruction was performed using a filtered back projector method with a Shepp-Logan Hanning filter and a cut-off frequency of 0.4. The surgical defect on one side of the jaw was treated with the sandwich unit with Bio-oss particulate bone within it, while the other side contained the same quantity of Bio-oss as in the left side but just covered with interceed membrane. The osteoblastic uptake on the side with the classical sandwich was compared to the side with the particulate bone covered with interceed membrane for dynamic physiological activities. The average activity for both sides was calculated and compared. For all the 12 sites, osteoblastic activities were recorded and indicated that vascularized bone was formed at all the experimental sites. Autogenous bone graft was confirmed to be superior to xenograft using this sandwich technique. Furthermore, the osteoblastic activities on the sandwich side were seen to be more when compared with the control side (Interceed side). The Ogunsalu sandwich bone regeneration technique has been successfully evaluated with SPECT which shows osteoblastic activity with formation of vascularized bone which integrates with the surrounding bone.
- [Show abstract] [Hide abstract] ABSTRACT: Various bone regeneration techniques have evolved recently but controversies regarding vascularization and integration of such bone grafting techniques have led occasionally to animal experiment to validate such techniques. The objective of this study was to evaluate the evidence of vascularization and osseo-integration of a new bone regeneration technique utilized for the closure of oro-antral communication (OAC) by an experimental model in which Single Photon Emission computerized Tomography and histological studies were conducted in pigs. We conclude that the sandwich technique used for the closure of OAC results in a vascularized new bone formation which eventually osseo-integrate with the surrounding bone. Also, this experimental study confirmed that autogeneous bone graft was superior to xenografts when used within the sandwich unit.
The University of the West Indies, Trinidad and TobagoCity of Port-of-Spain, City of Port of Spain, Trinidad and Tobago