Publications (1)2.35 Total impact

  • Zhen-Liang Sun · Ying Wang · Mei-Li Guo · Yu-Xian Li
    [Show abstract] [Hide abstract]
    ABSTRACT: Two new oleanolic acid saponins, namely celosin C (1) and celosin D (2), were isolated from the ethanol extract of Semen celosiae. Their structures were identified as celosin C (1) and celosin D (2) by spectroscopic and chemical analyses. The hepatoprotective activity of 1 and 2 with oral dose 1.0, 2.0 and 4.0 mg/kg, respectively, were investigated by carbon tetrachloride (CCl(4))-induced hepatotoxicity in mice. The results indicate that they have significant hepatoprotective effects (p<0.01).
    No preview · Article · Nov 2009 · Fitoterapia