Article

Faecal enema as an adjunct in the treatment of Pseudomembranous Enterocolitis

Surgery (Impact Factor: 3.38). 12/1958; 44(5):854-9.
Source: PubMed
28 Followers
 · 
406 Reads
    • "First reported in humans in 1958 ( Eiseman, Silen, Bascom, & Kauvar, 1958 ), recent clinical trials have shown FMT as an effective treatment for recurrent CDI (Gough, Shaikh, & Manges, 2011; Karadsheh & Sule 2013 ) with mixed results for other disease processes (Rubin, 2013). The FDA also recently updated the draft guidance for the use of FMT in the treatment of recurrent CDI not responding to standard therapies ( U.S. FDA, 2014 ). "
    [Show abstract] [Hide abstract]
    ABSTRACT: Fecal microbiota transplantation (FMT) is an investigational biologic drug for the treatment of recurrent Clostridium difficile infection (CDI). It is hypothesized to alleviate disease symptoms by modulating dysbiosis, the microbial imbalance in a patient’s intestinal tract ( Samuel, Crumb, & Duba, 2014 ). As self-administration of FMT at home is on the rise ( Silverman, Davis, & Pillai, 2010 ; Duke & Fardy, 2014 ), nurses need to understand their role in bridging the gap between the patient and healthcare team. A description of complications experienced by a toddler after home-administered FMT is followed by discussion on its implications for nursing practice.
    No preview · Article · Jan 2016 · Gastroenterology Nursing
  • Source
    • "Furthermore a pseudomembranous enterocolitis case with severe diarrhea related to antibiotics was treated through a fecal enema (Eiseman et al. 1958). "

    Full-text · Article · Jan 2016 · Turk psikiyatri dergisi = Turkish journal of psychiatry
  • Source
    • "Le transfert de microbiote fécal (TMF) aussi appelé transplantation de microbiote fécal, bactériothérapie fécale ou transfert de flore, consiste à introduire une préparation constituée d'une dilution de selles d'un donneur sain dans le tube digestif d'un patient receveur, afin de rééquilibrer le microbiote altéré de l'hôte (dysbiose). Cette approche thérapeutique, décrite dans la médecine chinoise [1] dès le IV e siècle, a suscité un intérêt grandissant suite à la publication en 1958 de la guérison spectaculaire après un TMF de quatre patients atteints de colite pseudomembraneuse [2]. Depuis, cette technique a fait l'objet de très nombreuses études montrant son incontestable efficacité dans le traitement des infections récidivantes à Clostridium difficile (CD). "

    Full-text · Article · Mar 2015 · Annales Pharmaceutiques Françaises
Show more