Article

The ECAT ART Scanner for Positron Emission Tomography. 1. Improvements in Performance Characteristics.

PET Facility, Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA
Clinical Positron Imaging 02/1999; 2(1):5-15. DOI: 10.1016/S1095-0397(98)00057-0
Source: PubMed

ABSTRACT

The widespread use of positron emission tomography (PET) has been to some extent limited by the cost and complexity of PET instrumentation. Recognition of the wider applicability of clinical PET imaging is reflected in the ECAT ART design, a low cost PET scanner targeted for clinical applications, particularly in oncology. The ART comprises two asymmetrically opposed arrays of BGO block detectors. Each array consists of 88 (transaxial) by 24 (axial) crystals, and the arrays rotate continuously at 30 rpm to acquire a full 3D projection data set. Sensitivity and count rate limitations are key performance parameters for any imaging device. This paper reports on improved performance characteristics of the ART, achieved by operating the scanner with a decreased block integration time, reduced coincidence time window, and collimated singles transmission sources. Compared to the standard ART configuration, these modifications result in both improved count rate performance and higher quality transmission scans.

0 Followers
 · 
3 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: The ECAT ART is a low-cost positron emission tomography (PET) scanner design for which increasing interest in the use of PET, and specifically (18)FDG PET for oncological studies, has stimulated a demand. Although targeted primarily for the clinical market, the performance of the ART scanner can also meet the demands of a research environment where, in addition to [(18)F], more challenging, shorter-lived isotopes such as [(11)C], [(13)N] and [(15)O] are used. The ART has been used successfully to perform quantitative (18)FDG studies, blood flow measurements with [(15)O]water, and brain mapping studies with [(15)O]water (activation). In the clinical arena, it has been used for a wide range of applications, including epilepsy, whole-body imaging in oncology, and for cardiac viability studies. This paper explores the capability of the ECAT ART scanner to meet the demands of PET studies in both a research and clinical arena.
    No preview · Article · Feb 1999 · Clinical Positron Imaging
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Nuclear Medicine is the specialty of medical imaging, which utilizes a variety of radionuclides incorporated into specific compounds for diagnostic imaging and therapeutic applications. During recent years, research efforts in this discipline have concentrated on the decay characteristics of particular radionuclides and the design of unique radiolabeled tracers necessary to achieve time-dependent molecular images. Various oncology applications have utilized specific PET and SPECT radiopharmaceuticals, which have allowed an extension from functional process imaging in tissue to pathologic processes and nuclide directed treatments. One of the most widely recognized advantages of positron emission tomography (PET) is its use of the attractive, positron-emitting biologic radiotracers that mimic natural substrates. However, a major disadvantage is that these substances are relatively short-lived and unable to be transported great distances. At this time, economic considerations and regulatory guidelines associated with the creation of a PET facility, as well as the operational costs of maintaining both the facility and the necessary procedural documentation, continue to create interesting strategic dilemmas. This commentary will focus on the current approach and anticipated impact of pending regulations, which relate to the manufacture and formulation of a variety of PET radiopharmaceuticals used in clinical research and patient management at Memorial Hospital.
    Preview · Article · Jan 2000 · Annals of Nuclear Medicine
  • [Show abstract] [Hide abstract]
    ABSTRACT: Computed tomography (CT) is a widely-used anatomical imaging modality that was introduced in the early 1970s [1] and appeared in clinical practice a few years later [18,32]. CT offers good spatial resolution and low levels of statistical noise, resulting in morphological images of high quality. In general, radiological imaging techniques reveal anatomical changes, such as tumor development, associated with the underlying functional abnormality.
    No preview · Article · Jan 2000
Show more

Similar Publications