Evidence for the interruption of transmission of lymphatic filariasis among schoolchildren in Trinidad and Tobago

Caribbean Epidemiology Centre (CAREC), P.O. Box 164, Port of Spain, Trinidad and Tobago.
Transactions of the Royal Society of Tropical Medicine and Hygiene (Impact Factor: 1.84). 09/2004; 98(8):473-7. DOI: 10.1016/j.trstmh.2003.11.006
Source: PubMed


This study was carried out to provide some evidence for the interruption of transmission of lymphatic filariasis (LF) among schoolchildren in Trinidad and Tobago. A cross-sectional survey for LF antigenaemia was performed among 63 (13.2%) of the 479 primary schools located in eight administrative (and geographical) regions of Trinidad and Tobago. From these communities, 2597 schoolchildren aged 6-12 years were sequentially selected for a survey of bancroftian antigenaemia. From each child, 100 microl (finger-prick) whole blood sample was applied to a Binax immunochromatographic card test (ICT), and read for the presence of antigenaemia. The ICT results showed a negative finding for LF antigenaemia and suggest that LF transmission has been interrupted in the survey areas.

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    • "t were successful in the earlier phase of the program may no longer be adequate because of issues with sensitivity , the requirement for larger sampling sizes , and lag phases before Mf or CFA are detectable in newly infected persons ( Burkot et al . , 2002 ; Ramzy , 2002 ; Durrheim et al . , 2003 ; Lammie et al . , 2004 ; Melrose et al . , 2004 ; Rawlins et al . , 2004 ; Grady et al . , 2007 ; Weil and Ramzy , 2007 ; Ramaiah et al . , 2009 ) ."
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