Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study)

ArticleinThe American Journal of Cardiology 94(3):384-6 · September 2004with3 Reads
Impact Factor: 3.28 · DOI: 10.1016/j.amjcard.2004.04.044 · Source: PubMed


    We studied 4,963 participants of the population-based Rotterdam Study and found that a genetically determined chronic exposure to low insulin-like growth factor-I (IGF-I) levels is associated with an increased risk for heart failure in elderly patients.