Infrequent Reinfection after Successful Treatment for Hepatitis C Virus Infection in Injection Drug Users

Cornell University, Итак, New York, United States
Clinical Infectious Diseases (Impact Factor: 8.89). 12/2004; 39(10):1540-3. DOI: 10.1086/425361
Source: PubMed


We followed-up 18 injection drug users for a mean of 33.8 months (range, 4-55 months) after successful treatment for hepatitis C virus (HCV) infection. Fifteen (83%) of the patients remained HCV RNA-negative, 1 patient was not tested, and 2 patients had test results positive for HCV RNA. The estimated rate of reinfection as a result of injection drug use was 0-4.1 cases per 100 person-years (cumulative incidence, 0%-12.6% at 48 months after completion of treatment). Of 50 patients originally treated, 15 (30%) were HCV RNA-negative 3 years later.

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