Plasma aldosterone levels in the 1st week of life in infants of less than 30 weeks gestation

ArticleinEuropean Journal of Pediatrics 164(3):141-5 · April 2005with3 Reads
Impact Factor: 1.89 · DOI: 10.1007/s00431-004-1572-0 · Source: PubMed
Abstract

Plasma aldosterone levels were measured in 50 infants of less than 30 weeks gestation at 24 h (D1) and 7 days (D7). The relationship between the plasma aldosterone level and a number of clinical and biochemical variables was explored. Plasma aldosterone levels ranged from 1000 to 30000 pmol/l and were inversely correlated with the severity of illness (D1 or D7), serum sodium (D7) and 24 h sodium intake (D1). No correlation with the serum potassium level was noted. Conclusion:Plasma aldosterone levels in this extremely premature cohort were significantly greater than those reported in more mature infants. Important determinants were severity of illness and sodium homeostasis.

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