Detection of t(14;18)(q32;q21) in B-cell chronic lymphocytic leukemia

ArticleinArchives of pathology & laboratory medicine 129(3):410-1 · April 2005with2 Reads
Impact Factor: 2.84 · DOI: 10.1043/1543-2165(2005)129<410:DOQIBC>2.0.CO;2 · Source: PubMed


    Cytomorphologic testing and multiparameter flow cytometry are the mainstays in diagnosing B-cell chronic lymphocytic leukemia, whereas fluorescence in situ hybridization that targets the translocation t(14;18)(q32;q21) often is used to identify follicular lymphoma. Therapy is highly diverse between both diseases. We describe a case with cytomorphologically and immunologically proven B-cell chronic lymphocytic leukemia in which t(14;18)(q32;q21) was found.