Sudden, Unexpected Death Associated with Meningioangiomatosis: Case Report

University of California, San Diego, San Diego, California, United States
Pediatric and Developmental Pathology (Impact Factor: 0.87). 04/2005; 8(2):240-4. DOI: 10.1007/s10024-004-9105-4
Source: PubMed


We report a case of sudden, unexpected death associated with meningioangiomatosis in a 13-year-old, previously healthy male without a history of seizures, neurologic deficits, or clinical stigmata of neurofibromatosis. There was no family history of neurofibromatosis. The postmortem examination showed a 5-cm mass involving the right posterior frontal and orbital frontal cortex that had microscopic features diagnostic of meningioangiomatosis. Because no other cause of death was found, we postulate that he likely died as a result of a seizure secondary to meningioangiomatosis.

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    • "In cases of intractable seizures, resection is indicated(Jallo et al., 2005). At least one case of sudden death, presumably secondary to a fatal seizure, has been reported involving a previously-asymptomatic 13-year old boy(Wixom et al., 2005). "

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