Review paper: Surface Modification for Bioimplants: The Role of Laser Surface Engineering

Department of Materials Science and Engineering, The University of Tennessee, Knoxville, 37996, USA.
Journal of Biomaterials Applications (Impact Factor: 2.2). 08/2005; 20(1):5-50. DOI: 10.1177/0885328205052974
Source: PubMed


Often hard implants undergo detachment from the host tissue due to inadequate biocompatibility and poor osteointegration. Changing surface chemistry and physical topography of the surface influences biocompatibility. At present, the understanding of biocompatibility of both virgin and modified surfaces of bioimplant materials is limited and a great deal of research is being dedicated to this aspect. In view of this, the current review casts new light on research related to the surface modification of biomaterials, especially materials for prosthetic applications. A brief overview of the major surface modification techniques has been presented, followed by an in-depth discussion on laser surface modifications that have been explored so far along with those that hold tremendous potential for bioimplant applications.

    • "Laser surface structuring can improve key properties of components , such as tribological behaviour [1], wettability [2], biological performance [3], optical reflectivity [4], and adhesion stability [5]. Depending on the used laser type and machining strategy surface patterning in micrometric to nanometre scale is achievable [6]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: In this work, the use of ns-pulsed fibre laser for surface structuring of AZ31 Mg alloy is investigated. Surface re-melting was employed to change surface morphology, especially in terms of surface roughness. Dimpling by percussion microdrilling was investigated to control the hole geometry.. With surface remelting mono-directional and homogeneous surfaces were obtained with Fl<500 J/cm2. Above 500 J/cm2 particle generation was observed, which induced sub-micron structure growth with nano-fibrous features. Moreover, surface roughness could be controlled below the initial value and much higher. With dimpling, transformation from gentle to strong ablation was observed at F0=10.3 J/cm2. XRD analysis was employed to link oxide growth to the surface morphology. Tensile tests were carried out to assess the damage on the mechanical properties after surface structuring.
    No preview · Article · Dec 2015 · Optics & Laser Technology
    • "Just like other biomaterials, DMLS biomaterials need to present good mechanical and corrosion properties, high wear resistance as well as to improve bioactivity and osseointegration of the metal implant. However, as Kurella and Dahotre [13] clearly expressed 0264-1275/Ó 2015 Elsevier Ltd. All rights reserved. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Direct metal laser sintering (DMLS) is a powerful tool to produce titanium based biomaterials because the ease to convert 3D medical imaging data into solid objects with excellent mechanical and corrosion properties. DMLS samples can be functionalized by anodizing, allowing the growth of titanium oxide layers of enhanced properties. In the present paper, a complete characterization of the microstructure, mechanical properties and particularly, the corrosion behavior has been carried out to assess their possible use as biomaterial. The results of the anodized scaffolds are very promising, showing a Young Modulus near to the cortical bone and a low corrosion rate, ensuring their suitability for medical applications.
    No preview · Article · Oct 2015 · Materials & design
  • Source
    • "The adhesion strength was also found to be increased in laser irradiated surface [22]. In the past, laser surface texturing was successfully applied to improve wettability, protein and cell adhesion [12] [23] [24]. Hence, from the above mentioned discussions it may be concluded that in the past several studies have been done on the effect of laser surface texturing on biocompatibility like protein adsorption , cell attachments, proliferation, etc. "
    [Show abstract] [Hide abstract]
    ABSTRACT: The present study concerns a detailed understanding of wear, corrosion and bio-activity behaviors of laser surface textured titanium alloy (Ti–6Al–4V) with line and dimple geometry developed by ArF excimer laser at a wavelength of 193 nm with a pulse length of 5 ns. The mechanical properties of the surface have been evaluated by measuring nano-hardness and wear resistance. The corrosion resistance property has also been evaluated in Hank's solution. The effect of laser surface texturing on bioactivity and cell attachment has also been studied. Laser surface texturing led to an increase in nano-hardness to a value of 4–6 GPa as compared to 2 GPa of the as-received Ti–6Al–4V. Furthermore, laser modified surfaces showed a significant increase in wear resistance and a marginal change in corrosion resistance. Textured surface shows a significant improvement in bioactivity in terms of calcium phosphate deposition rate in Hank's solution. XTT result shows, comparable cell viability of laser textured Ti–6Al–4V as that of as received Ti-alloy. Cell attachment study shows a reduced cell density in textured surface with a maximum reduction in dimple textured surface. Cells aligned themselves along the direction of texturing in linear textured surface.
    Full-text · Article · Sep 2015 · Applied Surface Science
Show more