Papillary adenofibroma of the cervix: a case report. Ultrasound Obstet Gynecol

SSK Maternity and Health Teaching Hospital, Gynecology, Ankara, Turkey.
Ultrasound in Obstetrics and Gynecology (Impact Factor: 3.85). 08/2005; 26(2):186-7. DOI: 10.1002/uog.1948
Source: PubMed


Adenofibroma is an extremely rare benign biphasic neoplasm that is classified into the mixed epithelial and mesenchymal tumor group. It typically affects the endometrium, but may occur in the cervix or in an extrauterine location. Preoperative diagnosis of this tumor is usually difficult. We describe the case of a 55-year-old woman with papillary cervical adenofibroma, which appeared as a cervical mass containing multiple cystic components on transvaginal ultrasound. This lesion appears to be clinically and histologically benign but must be differentiated from malignant lesions of the uterus, particularly from adenosarcoma, which can be suggestive of adenofibroma. Accurate diagnosis of these benign tumors permits appropriate counseling of patients.

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    • "Endometrial adenofibroma is a rare benign mullerian mixed tumor composed of benign epithelial and mesenchymal components. The major proportion of adenofibromas arise from the endometrium (90%); less often occur in the cervix [1] and in other anatomical locations. When this tumor arises in the cervix, women can present with abnormal vaginal bleeding, as a first sign. "
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    ABSTRACT: Adenofibroma is an extremely uncommon benign tumor composed of glandular and fibrous tissues. It occurs more often in the endometrium but it can also occur in the cervix and extrauterine sites. We report a case of a 32-year-old asymptomatic woman with cervical adenofibroma, first detected in a routine endovaginal ultrasound, as a cervical mass containing multiple cystic components. Histopathologic findings diagnosed its nature. As adenofibromas are very rare, we present this case with a brief review of the literature.
    Full-text · Article · Dec 2013
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    • "The imaging techniques did not help to locate the exact origin of the tumor and to exclude malignancy in our patient. Although the unique sonographic finding of uterine adenofibroma was described, it was not diagnostic and inconclusive to exclude malignant component [7, 9]. "
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    ABSTRACT: Adenofibroma is an extremely rare benign biphasic neoplasm that is classified into the mixed epithelial and mesenchymal tumor group. These tumors tend to occur in postmenopausal and elderly women. We report the case of a large polypoidal mass per vagina occupying the whole pelvis in a young woman. Preoperative biopsy showed benign epithelial and mullerian mesenchymal components suggestive of mullerian adenofibroma. Total hysterectomy with bilateral salpingectomy was done. The diagnosis of papillary adenofibroma of cervix was made. The total surgery assured complete excision and permitted adequate sampling to exclude malignancy.
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