Risk factors for rehospitalization in COPD : Health status, anxiety and depression

Uppsala University, Uppsala, Uppsala, Sweden
European Respiratory Journal (Impact Factor: 7.64). 10/2005; 26(3):414-9. DOI: 10.1183/09031936.05.00078504
Source: PubMed


The aim of the present study was to analyse the risk of rehospitalisation in patients with chronic obstructive pulmonary disease and associated risk factors. This prospective study included 416 patients from a university hospital in each of the five Nordic countries. Data included demographic information, spirometry, comorbidity and 12 month follow-up for 406 patients. The hospital anxiety and depression scale and St. George's Respiratory Questionnaire (SGRQ) were applied to all patients. The number of patients that had a re-admission within 12 months was 246 (60.6%). Patients that had a re-admission had lower lung function and health status. A low forced expiratory volume in one second (FEV1) and health status were independent predictors for re-admission. Hazard ratio (HR; 95% CI) was 0.82 (0.74-0.90) per 10% increase of the predicted FEV1 and 1.06 (1.02-1.10) per 4 units increase in total SGRQ score. The risk of rehospitalisation was also increased in subjects with anxiety (HR 1.76 (1.16-2.68)) and in subjects with low health status (total SGRQ score >60 units). When comparing the different subscales in the SGRQ, the closest relation between the risk of rehospitalisation was seen with the activity scale (HR 1.07 (1.03-1.11) per 4 unit increase). In patients with low health status, anxiety is an important risk factor for rehospitalisation. This may be important for patient treatment and warrants further studies.

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Available from: Gunnar Gudmundsson
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    • "breathing difficulties. HADS is sensitive to treatment changes (Herrmann 1997) and has been used in studies with people having COPD in Iceland (Gudmundsson et al. 2005, Ingadottir & Jonsdottir 2010). International Physical Activity Questionnaire short version (IPAQ) contains seven questions to assess self-reported physical activity of different intensity: walking, moderateintensity and vigorous-intensity. "
    Dataset: G55

    Full-text · Dataset · Feb 2016
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    • "The progression of the disease is gradual and many people may have it without being aware of it (Pena et al. 2000, Benediktsdottir et al. 2007). Consequently, there needs to be an emphasis on the more latent aspects of being a smoker and living with COPD, particularly shame and guilt (Arne et al. 2007, Lindqvist & Hallberg 2010, Halding et al. 2011) and anxiety and depression (Gudmundsson et al. 2005, Goodwin et al. 2012). Anxiety and depression negatively influence the prognosis of COPD (Atlantis et al. 2013) and HRQL (Blakemore et al. 2014). "
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