A Randomized Evaluation of Quality-of-Life Therapy with Patients Awaiting Lung Transplantation

Center for Behavioral Health Research in Organ Transplantation and Donation, University of Florida, Gainesville, Florida, USA.
American Journal of Transplantation (Impact Factor: 5.68). 11/2005; 5(10):2425-32. DOI: 10.1111/j.1600-6143.2005.01038.x
Source: PubMed


Research shows that patients wait-listed for lung transplantation have very poor quality of life (QOL). This study evaluated the effectiveness of Quality-of-Life Therapy (QOLT) in improving QOL, mood disturbance and social intimacy in adults awaiting lung transplantation. Thirty-five adults were randomized to QOLT (n = 17) or supportive therapy (ST; n = 18) and received individual, telephone-based treatment sessions. QOL, mood and social intimacy assessments were conducted at baseline and at 1 and 3 months after treatment. Repeated measures analyses of variance showed significant Condition x Time interaction effects for all three primary outcome measures. Subsequent post hoc analyses showed that the two groups did not differ significantly at baseline, but did differ significantly at the 1- and 3-month follow-up assessments. When compared to ST patients, QOLT patients had significantly higher QOL scores at the 1- and 3-month assessments, lower mood disturbance scores at the 3-month assessment, and higher social intimacy scores at the 1-month assessment. Results indicate that a patient's QOL, mood state and relationship with the primary caregiver can be positively impacted by a brief psychological intervention prior to lung transplantation.

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    • "Client and therapist attempt to change the circumstances, attitudes, standard of fulfillment, and relative importance of selected two to five domains. Among adults awaiting lung transplantation, individuals receiving telephone-based quality of life therapy demonstrated significantly higher quality of life at 1- and 3-month follow-up assessments.125 Meanwhile, well-being therapy126 is based on Ryff's model of psychological well-being.127 "
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    • "Three patient-centered intervention studies, which focused on psychological distress and coping during the waiting period, showed that interventions improve psychological measures of depression and anxiety [15–17]. Lung transplant candidates use adaptive problem and emotion focused coping strategies [18]. "
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