Actigraphy Correctly Predicts Sleep Behavior in Infants Who Are Younger than Six Months, When Compared with Polysomnography

Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.
Pediatric Research (Impact Factor: 2.31). 11/2005; 58(4):761-5. DOI: 10.1203/01.PDR.0000180568.97221.56
Source: PubMed


Actigraphy has been widely used in adults and children. In infants, validation of actigraphy has typically used a comparison with behaviorally determined sleep state classification rather than polysomnography (PSG). This study validated actigraphy against PSG for determining sleep and waking states in infants who were younger than 6 mo. Twenty-two healthy infants, 13 term and 9 preterm, were studied at three different matched postconceptional ages. Actigraph data were compared with PSG recordings in 1-min epochs. Agreement rate (AR), predictive value for sleep, predictive value for wake, sensitivity. and specificity were calculated and compared between activity thresholds and across ages with two-way ANOVA for repeated measures. Thirty-two validation studies were analyzed. Overall AR with PSG of 93.7 +/- 1.3 and 91.6 +/- 1.8 were obtained at 2-4 wk and 5-6 mo, respectively, at the low activity threshold setting, whereas the auto activity threshold gave the best agreement with PSG at 2-4 mo (AR 89.3 +/- 1.3%). Sensitivity values of 96.2 +/- 1.1% at 2-4 wk, 91.2 +/- 1.5% at 2-4 mo, and 94.0 +/- 1.9% were obtained at these same settings. There was no difference across ages in AR or sensitivity. PVW and specificity values were low in this study. We conclude that actigraphy is a valid method for monitoring sleep in infants who are younger than 6 mo.

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Available from: Rosemary S C Horne, Mar 18, 2015
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    • "Actigraphy has been validated in infants younger than 6 months using behavioral state evaluations and polysomnography (So, Buckley, Adamson, & Horne, 2005), with high sensitivity values of 96.2 (1.1%) in the neonatal period (So et al., 2005); furthermore, it enables a double-blind experimental paradigm. Actigraphy has been used successfully, specifically with preterm newborns in nurseries (Chang, Anderson, & Lin, 2002;Gertner et al., 2002;So et al., 2005). "

    Full-text · Dataset · Jan 2016
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    • "Detected movement is coded as sleep or wake by established algorithms that utilise the decreased proportion of movement associated with sleep. Actigraphy has been used for the assessment of sleep patterns in the pediatric population [11] [12] and has been validated to assess sleep and wake in premature infants in a neonatal intensive care unit (NICU) setting [13]. Non-invasive respiratory support is widely used both as a primary therapy and post-extubation modality of respiratory support in preterm infants. "
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    ABSTRACT: Aim: To determine whether respiratory support via heated humidified high flow nasal cannulae (HHHFNC) results in infants <32weeks gestation spending a greater proportion of time in sleep compared to those receiving nasal continuous positive airway pressure (NCPAP). Methods: A subgroup of infants enrolled in a randomized controlled trial to compare HHHFNC or NCPAP post-extubation had sleep and wake activity measured by actigraphy for 72hours post-extubation. Activity diaries were completed contemporaneously to record episodes of infant handling. Actigraphy data were downloaded with known periods of handling excluded from the analysis. Results: 28 infants with mean gestation of 28.3weeks (SD 2) and birth weight 1074g (SD 371) were studied. Infants receiving HHHFNC spent a lesser proportion of time in sleep 59.8% (SD 18.5) than those on NCPAP 82.2% (SD 23.8) p=0.004. Infants receiving HHHFNC had a lower sleep efficiency and higher mean activity score than those on NCPAP (p=0.003, p=0.002, respectively). Conclusion: Infants receiving HHHFNC had a higher mean activity score and spent less time in sleep than those allocated NCPAP. Further study of sleep wake activity in preterm infants receiving respiratory support is required as this may impact on neurodevelopmental outcomes.
    Full-text · Article · Nov 2015 · Early human development
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    • "No defined algorithm to analyze the sleep and activity pattern of preterm infants is described in the literature. For that reason, we used the algorithm of So et al. (2005), which was developed for neonates of an age between 2 and 4 weeks. The intensity of activity is divided into three categories. "

    Full-text · Dataset · Jul 2015
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