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Case records of the Massachusetts General Hospital. Case 30-2005. A 56-year-old man with fever and axillary lymphadenopathy.

Division of Infectious Diseases, University of California at San Francisco, San Francisco, USA.
New England Journal of Medicine (Impact Factor: 55.87). 10/2005; 353(13):1387-94.
Source: PubMed
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    • "While immunocompetent individuals may not even need treatment for CSD, it is generally recommended that those with immunodeficiency states such as AIDS and transplantation received prolonged courses (at least 3 months) of antimicrobial therapy.16 Short courses of therapy that may suffice in otherwise healthy hosts may not be adequate in transplant recipients. "
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    ABSTRACT: Cat scratch disease has been reported very rarely in cardiac transplant recipients. In a review of 1073 episodes of infection in 620 heart transplant patients over a 16 year period, only one case of infection secondary to Bartonella henselae was documented. Another case of hepatosplenic bacillary angiomatosis from B. henselae was reported 2 decades ago in a heart transplant recipient who had presented with fevers of unknown origin. Although the typical clinical manifestation is that of a skin lesion accompanied with lymphadenopathy, cat scratch disease may present with persistent fevers without a clinically overt infective focus in immunosuppressed individuals. Moreover, more than one disease process may coexist in immunocompromised hosts. While the lymphadenopathy in our patient was secondary to Cat scratch disease, interestingly, the adjacent skin lesion that was thought to represent unhealed site of inoculation of Bartonella was diagnosed as squamous cell carcinoma.
    Full-text · Article · Jan 2012 · Infectious disease reports
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    • "Borrelia burgdorferi infection (Lyme disease) has been described in the literature in transplant recipients, including 1 kidney transplant recipient [14] , 1 heart transplant recipient (with car- ditis) [15], and 1 allogeneic hematopoietic stem cell transplant recipient [16]. Bartonella henselae infection has been described after heart [9] and kidney transplantation10111213, with variations in the manifestation of infection that include hemophagocytosis [137], closely associated acute allograft rejection [10], peliosis hepatis [138], peliosis hepatitis and hepatorenal syndrome [139], pulmonary nodules [140], and osteomyelitis [141] . Brucella species infection has been reported after kidney trans- plantation [21, 22] and as a donor-derived infection during HSCT [23], mostly in areas of endemicity. "
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    ABSTRACT: Numerous reports exist of the transmission of zoonoses to humans during and after solid-organ and hematopoietic stem cell transplantation. Donor-derived infections of numerous etiologies, including West Nile virus infection, Chagas disease, toxoplasmosis, rabies, lymphocytic choriomeningitis virus infection, and infection due to Brucella species have been reported. Most zoonoses occur as a primary infection after transplantation, and immunocompromised patients are more likely to experience significant morbidity and mortality from these infections. Risks of zoonotic infection in the posttransplantation period could be reduced by patient education. Increased recognition of the risks of zoonoses, as well as the advent of molecular biolog-based testing, will potentially augment diagnostic aptitude. Documented zoonotic infection as it affects transplantation will be the primary focus of this review.
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    ABSTRACT: La survenue d'adénopathies chez un patient traité par anti-TNF-α fait redouter l'existence d'une tuberculose ganglionnaire ou d'une hémopathie. La mise en évidence d'une réaction granulomateuse oriente vers une tuberculose. De nombreuses autres infections responsables d'une réaction granulomateuse ont été rapportées chez les patients traités par anti-TNF-α. Nous rapportons une observation où des adénopathies granulomateuses chez un patient traité par étanercept pour une spondylarthrite ankylosante étaient secondaires à une infection à Bartonella henselae.
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