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Relationship Between Distance of Schools from the Nearest Municipal Waste Incineration Plant and Child Health in Japan

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In Japan, the main source of dioxins is incinerators. This study examined the relationship between the distance of schools from municipal waste incineration plants and the prevalence of allergic disorders and general symptoms in Japanese children. Study subjects were 450,807 elementary school children aged 6-12 years who attended 996 public elementary schools in Osaka Prefecture in Japan. Parents of school children completed a questionnaire that included items about illnesses and symptoms in the study child. Distance of each of the public elementary schools from all of the 37 municipal waste incineration plants in Osaka Prefecture was measured using geographical information systems packages. Adjustment was made for grade, socioeconomic status and access to health care per municipality. Decreases in the distance of schools from the nearest municipal waste incineration plant were independently associated with an increased prevalence of wheeze, headache, stomach ache, and fatigue (adjusted odds ratios [95% confidence intervals] for shortest vs. longest distance categories =1.08 [1.01-1.15], 1.05 [1.00-1.11], 1.06 [1.01-1.11], and 1.12 [1.08-1.17], respectively). A positive association with fatigue was pronounced in schools within 4 km of the second nearest municipal waste incineration plant. There was no evident relationship between the distance of schools from such a plant and the prevalence of atopic dermatitis or allergic rhinitis. The findings suggest that proximity of schools to municipal waste incineration plants may be associated with an increased prevalence of wheeze, headache, stomach ache, and fatigue in Japanese children.
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... 7 A study on children found no relation between incinerator operation and the incidence of allergic rhinitis or atopic dermatitis within populations in the surrounding area. 8 However, a study reported increased blood polychlorinated dibenzo-p-dioxins/dibenzofurans concentrations in residents living near incinerators and incinerator workers. 9 Also, emissions of carcinogenic substances (chromium, arsenic, cadmium, and nickel) by incinerators in a new city exceeded the levels permitted by the Ministry of Environment. ...
... There was no correlation between proximity to incinerators and asthma, allergic rhinitis, or atopy in children. 8 Further studies are needed to address these differences in children and adults. ...
... In a similar study conducted in young adult in Japan, there was no evident relationship between the distance from incinerator and the prevalence of allergic rhinitis. 8 Depending on the size, combustion type and the actual emission of hazardous substances, the impact on the prevalence of environmental diseases in the surrounding area of incinerator may be different. However, there are insufficient studies on the relationship among the residential area, period of residence and the prevalence of environmental diseases. ...
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Background: This study investigated the risk perceptions, prevalence of environmental diseases (EDs) and associated factors with the prevalence of environmental disease among the population living near an incinerator. Methods: Study area were divided into 3 local areas near the incinerator by distance (A, B, C) and control area (D) by distance and geographic isolation. A Questionnaire was conducted with 1,380 in local residents (A, B, C) and 390 in control area (D), gathered information of demographic characteristics, lifestyle, perception of damage by incinerators, experience of EDs (atopic dermatitis, allergic rhinitis, asthma) diagnosed by physician. Analysis of variance, χ2 test, and Kruskal Wallis test was applied to determine the difference by area. Logistic regression analysis was performed to identify factors associated with the prevalence of allergic rhinitis. Results: Residents residing closer to the incinerator had negative perception in most items in questionnaire compared with control. The prevalence of allergic rhinitis was higher as they lived nearby the incinerator (p = 0.008). The associated factors with the prevalence of allergic rhinitis were carpet (odds ratio [OR]: 1.79, p = 0.001), residential area (marginally significant), duration of residence (OR: 1.09, p < 0.001). The perception of environmental pollution around the residential area was inversely associated with the prevalence of allergic rhinitis: perceived as very dissatisfied (OR: 4.21, p = 0.02) compared with very satisfied. Conclusions: As closer to the incinerator, the risk perception tend to negative and prevalence of EDs were increased. Carpet, residential area, duration of residence and perception of environmental air pollution around the residential area were associated with prevalence of allergic rhinitis. These results may be useful for the communication with residents to discuss the environmental problems caused by the incinerator.
... 1. Pulmonary and skin ailments or symptoms -Decrease in the distance of schools from the nearest MSW incinerator plant were independently associated with an amplified pervasiveness of wheezing, headache and stomach ache. Miyake et al. (2005) captured landfill methane substituting fossil energy (CO 2 ) and from carbon stored for a long term in the landfill (United Nations Environment Programme, 2010). ...
... It was observed that there are no variations in the individuals' pulmonary health between an incineration community and its comparative community. Miyake et al. (2005) included 450,807 primary school students aged 6À12 in a cross-sectional research. This included distances between all 37 municipal trash incineration facilities and each of the 996 public elementary schools. ...
Chapter
In many cases, waste is dumped in an illegitimate way or in unmanaged landfills. These abhorrent practices exhibit a slew of environmental and health issues, including groundwater pollution, land deterioration, persistent cancer growth frequency, infant death and birth oddities. Residences near garbage sites have been associated with an amplified prevalence of premature infants, as it has the prevalence of numerous congenital abnormalities. There is scant evidence of a link between the vicinity of incinerators and reproduction or developmental impacts. Cancer prevalence and mortality studies in communities adjacent to landfills or incinerator plants have indeed been ambiguous, with differing results at different cancer sites. Most of these reports lack adequate individual or participant exposure records, as well as information on possible confounders such as socioeconomic status. The intrinsic latency of illnesses and population mobility are frequently overlooked. The probable health impacts of newer regimes in waste control/management and increased recycling and composting also necessitate more scientific evaluation and monitoring for their ecological vulnerabilities.
... 1. Pulmonary and skin ailments or symptoms -Decrease in the distance of schools from the nearest MSW incinerator plant were independently associated with an amplified pervasiveness of wheezing, headache and stomach ache. Miyake et al. (2005) captured landfill methane substituting fossil energy (CO 2 ) and from carbon stored for a long term in the landfill (United Nations Environment Programme, 2010 shipyard, iron foundry, incinerator and city centre. Lung cancer risk was correlated with the incinerator, with a disproportionately high risk at the site and a sharp decline distant from the incinerator. ...
... It was observed that there are no variations in the individuals' pulmonary health between an incineration community and its comparative community. Miyake et al. (2005) included 450,807 primary school students aged 6À12 in a cross-sectional research. This included distances between all 37 municipal trash incineration facilities and each of the 996 public elementary schools. ...
... V Itálii zjistili, že byl nárůst PM10 ze spalovny komunálního odpadu spojen se zvýšeným rizikem potratů (Candela et al., 2015). V Japonsku došli k závěru, že blízkost spalovny komunálních odpadů ke školám může být spojena s výskytem chrapotu, bolestí hlavy, bolestí žaludku a únavy u dětí školního věku (Miyake et al., 2005). ...
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English summary: In this study, we gradually went through the individual areas of the effects of waste incinerators on the environment, human health and the economy. One of the biggest problems associated with waste incineration is dioxins, which have serious negative effects on human health, including cancer, damage to the immune system, reproductive problems and developmental defects (Chapter 5.1.1). Although there are strict emission limits for them, waste incinerators are responsible for almost one fifth of all dioxins released into the air in the European Union (Chapter 5.1.1.1). It is evident that pyrolysis and plasma gasification of waste, as well as technologies now summarized under the name "chemical recycling" of plastic waste, do not represent functional substitutes for waste incineration and are similarly problematic in terms of environmental impacts or have different negative effects than "classical" waste incinerators (chapters 2 and 8). The most suitable alternatives in the field of waste management therefore appear to us to be waste prevention, sorting and recycling, which primarily includes bio-waste composting (Chapters 9.1.3 and 8). For municipal waste, the most appropriate solution is to set up systems called "zero waste" (see chapter 8.1), although it is clear that even in these systems some waste still remains. However, there is no need to build new waste incinerators for them, because the Czech Republic already has sufficiently large capacities for the energy recovery of waste. With their further growth, we are in danger of having to import waste, as in other countries, because cities will become dependent on W-t-E as heat sources (Chapter 10). Medical waste does not have to be incinerated to decontaminate infectious waste, there are a number of proven non-incineration technologies. Even in the healthcare sector, it makes sense to sort waste, not all of it is infectious (chapter 8.3). POPs in hazardous waste can be destroyed and decontaminated far more effectively by so-called non-incineration technologies (chapter 8.2.3), including ashes from incinerators containing high concentrations of dioxins (chapter 3.3.1). It is absolutely necessary to avoid incineration of waste containing mercury, which easily escapes even at normal (room) temperatures. Among other things, it is completely contrary to the Minamata Convention on mercury, which the Czech Republic ratified (chapter 8.2.2). Despite the claims of waste incineration plant operators that they have everything under control, the fact is that the most dangerous substances (such as dioxins or mercury) that are produced during combustion are monitored in emissions only twice a year, and many of them are not monitored at all (Chapters 3.1 and 5.1 .1.1). Due to emission limits, incinerators must clean the flue gas. However, it creates another flow of toxic waste in the form of ash and air pollution control (APC) residues, which must be dealt with somehow (chapters 3.3 and 5.1.1.3). Strict enough limits are not set for fly ash, and therefore, for example, a significant part of toxic substances, especially dioxins, escapes controlled disposal and thus significantly contributes to exceeding the planetary limits of chemical pollution (chapter 4.2). The amount of dioxins in fly ash out of control corresponds to the maximum tolerable intake of these substances for the population of up to 133 planets of the Earth. In addition to dioxins, other toxic substances such as brominated dioxins, PFASs, polychlorinated biphenyls and other organic substances are also released during waste incineration (Chapters 5.1 and 5.2). Brominated dioxins have similar toxicity to dioxins and similar effects on human health, yet they are not yet measured in flue gas from incinerators (this obligation is new), not to mention their concentration in solid waste incineration residues (chapter 5.1.2). Waste incinerators also release significant amounts of mercury and other toxic metals into the environment with negative effects on health (chapter 5.3). These metals are released into the air to a lesser extent but end up mainly in solid residues such as fly ash and APC residues and bottom ash. Unburnt plastic particles, known as microplastics, also remain in the ash (chapter 4.2). There are also many other potentially hazardous substances that are unknown or have no limits set for waste incinerators effluents (Chapter 5). This is problematic when considering the further use of residues from waste incinerators. In connection with exceeding the planetary limits for chemical pollution, there is no room for further pollution of the planet Earth. Despite the whole range of toxic substances that waste incinerators leave in emissions into the air and water, but above all in waste, slag, bottom ash and fly ash, the assessment of their impact on the health of residents living in the vicinity remains a controversial topic (Chapter 6). Although there have been a number of studies demonstrating their negative impact on human health, there are also a number of studies that have not proven this impact. Chapter 6 provides a rough cross-section of the issue of assessing the impact of incinerators on human health. However, it also concerns the assessment of local food contamination (chapters 3.4., 5.1.1.3.3 and 5.1.4.1). Waste incinerators do not only process materials that cannot be recycled, but they also compete for the same funds and materials with recycling facilities. At the same time, waste incineration means the loss of valuable raw materials, which must be extracted, produced and transported again. They thereby discourage the conservation of resources and their maintenance in a circular economy. Incinerators waste energy that was invested in the production of products that ended up in waste and in their collection. For these reasons, waste incineration was removed from the EU Taxonomy and from the list of financing sustainable activities. The construction of ZEVO and waste incinerators is heavily dependent on the financial support of the public sector (Chapters 9 and 10.1.1). He often paid extra for their construction or is paying extra. W-t-E receives support from EU funds in a hidden way. In addition to the initial investment costs, incinerators (W-t-E) swallow a lot of repair and maintenance funds, not counting the expenses related to the effects of incinerators on human health and the environment (Chapters 9.3, 9.4 and 9.5). Other financial costs are related to accidents, mostly fires, which occur quite often in waste incinerators, and which often destroy a large part of the equipment and threaten the health of residents living in the vicinity (Chapter 7). In the vicinity of the waste incinerators, soil contamination with toxic substances (primarily dioxins) and the related contamination of domestic poultry and/or livestock were also observed. Their research alone represented additional costs (chapters 3.4 and 9.5). Although some of their effects on the environment can still be debated because they have not been clearly proven, waste incinerators represent an outdated, unsustainable, and expensive way of managing waste that has negative effects on the environment, human health, and even the entire planetary ecosystem. Modern incinerators are trying to be included in the circular economy system and are therefore looking for ways to use the ash, which remains up to one third of its original weight from the incinerated waste (chapter 3.3.3). In this regard, too, for example, the oversized Dutch incinerators have already hit an imaginary ceiling, and the Nobel Prize winner Ernst Worrell therefore described the Dutch roads built from incinerator ash as "linear landfills" (chapter 3.3.3.1). Incinerating waste, while producing the energy that powers our modern, energy-intensive lives, also actively contributes to the cycle of climate change. Emissions of carbon dioxide, created by the combustion process, are one of the driving forces behind the greenhouse effect, which has serious consequences in the form of global warming and climate change. By 2050, the conversion of plastic waste to energy (including incineration in W-t-E) will lead to greater emissions of carbon dioxide than the burning of fossil fuels. Energy utilization of waste therefore does not help solve global climate change but contributes to it and thus represents a dead end in replacing coal (Chapter 4.1). While waste seems to magically disappear, the reality is that by burning waste we destroy valuable raw materials that we no longer can reuse, recycle or compost, while an unusable third of the original weight of waste remains enriched with toxic substances. By operating incinerators, we support linear waste management, which requires a constant supply of waste. xxxxxxxxxxxxxxxxxxxxxxxx V této studii jsme postupně prošli jednotlivé oblasti vlivů spaloven na životní prostředí, lidské zdraví i ekonomiku. Jedním z největších problémů spojených se spalováním odpadů jsou dioxiny, které mají vážné negativní účinky na lidské zdraví, včetně rakoviny, poškozování imunitního systému, reprodukčních problémů a vzniku vývojových vad (kapitola 5.1.1). Přestože pro ně existují přísné emisní limity, spalovny odpadů jsou zodpovědné za téměř jednu pětinu všech dioxinů vypouštěných do ovzduší v Evropské unii (kapitola 5.1.1.1). Je patrné, že pyrolýza a plazmové zplyňování odpadů stejně jako technologie nyní shrnované pod název „chemická recyklace“ plastových odpadů nepředstavují funkční náhrady za spalování a jsou z hlediska dopadů na životní prostředí podobně problematické anebo mají jiné negativní dopady než „klasické“ spalovny odpadů (kapitoly 2 a 8). Jako nejvhodnější alternativy v oblasti nakládání s odpady se nám proto jeví na prvním místě předcházení vzniku odpadů, jejich třídění a recyklace, které na prvním místě zahrnuje kompostování bioodpadů (kapitoly 9.1.3 a 8). Pro komunální odpady je nejvhodnějším řešením nastavení systémů zvaných „zero waste“ (nulový odpad, viz kapitolu 8.1), byť je jasné, že i v těchto systémech zatím nějaké odpady zbývají. Pro ty však není třeba stavět nové spalovny odpadů, protože Česká republika má již dostatečně velké kapacity pro energetické zhodnocení odpadů. Při jejich dalším růstu nám hrozí, že stejně jako v jiných zemích budeme muset odpady dovážet, protože města se stanou závislá na ZEVO jako zdrojích tepla (kapitola 10). Zdravotnické odpady se kvůli zbavení infekčnosti nemusejí spalovat, existuje řada osvědčených nespalovacích technologií. I ve zdravotnickém sektoru se vyplatí odpady třídit, ne všechny jsou infekční (kapitola 8.3). POPs lze v nebezpečných odpadech daleko účinněji rozložit a dekontaminovat tzv. nespalovacími technologiemi (kapitola 8.2.3), a to včetně popílků ze spaloven obsahujících vysoké koncentrace dioxinů (kapitola 3.3.1). Rozhodně je nutné se vyhnout spalování odpadů obsahujících rtuť, která snadno vytěkává už za normální (pokojové) teploty. Mimo jiné je to zcela v rozporu s Minamatskou úmluvou o rtuti, kterou Česká republika ratifikovala (kapitola 8.2.2). Navzdory tvrzením provozovatelů spaloven, že mají všechno pod kontrolou, je skutečnost taková, že ty nejnebezpečnější látky (například dioxiny nebo rtuť), které vznikají při spalování, jsou v emisích sledovány jen dvakrát ročně a mnoho z nich se nemonitoruje vůbec (kapitoly 3.1 a 5.1.1.1). Vzhledem k emisním limitům musí spalovny čistit spaliny. Tak však vytváří další tok toxického odpadu v podobě popílku a zbytků z čištění spalin, se kterým musí být nějak naloženo (kapitoly 3.3 a 5.1.1.3). Pro popílek nejsou nastaveny dostatečně přísné limity, a proto například značná část toxických látek, především dioxinů, uniká kontrolovanému nakládání a významně tak přispívá k překročení planetárních mezí chemického znečištění (kapitola 4.2). Množství dioxinů v popílcích mimo kontrolu odpovídá maximálnímu tolerovatelnému příjmu těchto látek pro populaci až 133 planet Zemí. Kromě dioxinů se při spalování odpadů uvolňují také další toxické látky, jako jsou bromované dioxiny, PFAS, polychlorované bifenyly a další organické látky (kapitoly 5.1 a 5.2). Bromované dioxiny mají podobnou toxicitu jako dioxiny a podobné účinky na lidské zdraví, přesto se ve spalinách ze spaloven zatím neměří (tato povinnost je nová), o jejich koncentraci v pevných zbytcích nemluvě (kapitola 5.1.2). Spalovny odpadů rovněž do prostředí uvolňují značné množství rtuti a jiných toxických kovů s negativními dopady na zdraví (kapitola 5.3). Tyto kovy jsou v menší míře uvolňovány do ovzduší, ale končí především v pevných zbytcích, jako je popílek a zbytky z čištění spalin a v popelu. V popelu dále zůstávají nespálené částečky plastů, známé jako mikroplasty (kapitola 4.2). Existuje také mnoho dalších potenciálně nebezpečných látek, o kterých se ve výstupech ze spaloven neví nebo pro ně neexistují limity (kapitola 5). To je problematické při úvahách o dalším využití zbytků ze spaloven odpadů. V souvislosti s překročením planetárních mezí pro chemické znečištění není prostor pro další znečišťování planety. I přes celou škálu toxických látek, které spalovny odpadů opouštějí v emisích do ovzduší a vody, ale především v odpadech, popelu a popílku, zůstává hodnocení jejich dopadů na zdraví obyvatel žijících v okolí kontroverzním tématem (kapitola 6). Vznikla sice řada studií prokazujících jejich negativní dopad i na lidské zdraví, ale je tu i řada studií, které tento dopad neprokázaly. Kapitola 6 podává hrubý průřez problematikou hodnocení dopadů spaloven na lidské zdraví. Týká se ho však i hodnocení kontaminace lokálních potravin (kapitoly 3.4., 5.1.1.3.3 a 5.1.4.1). Spalovny odpadů nezpracovávají pouze materiály, které nelze recyklovat, soutěží totiž o stejné finanční prostředky a suroviny s recyklačními zařízeními. Přitom znamená spalování odpadů ztrátu cenných surovin, které musí být znovu vytěženy, vyrobeny a dopraveny. Odrazují tím od zachování zdrojů a jejich udržení v cirkulárním hospodářství. Spalovny plýtvají energií, jež byla investována do produkce výrobků, které skončily v odpadu, a do jejich sběru. Z těchto důvodů bylo spalování odpadů vyřazeno z EU Taxonomy a ze seznamu financování udržitelných aktivit. Výstavba ZEVO a spaloven odpadů je silně závislá na finanční podpoře veřejného sektoru (kapitoly 9 a 10.1.1). Ten na jejich výstavbu často doplácel anebo doplácí. ZEVO dostávají skrytou cestou podporu z fondů EU. Kromě vstupních investičních nákladů spolykají spalovny (ZEVO) spoustu fondů na opravy a údržbu, nepočítaje výdaje související s dopady spaloven na lidské zdraví a životní prostředí (kapitoly 9.3, 9.4 a 9.5). Další finanční náklady souvisejí s haváriemi, většinou požáry, k nimž ve spalovnách dochází poměrně často, a které nezřídka zničí větší část zařízení a ohrozí zdraví obyvatel žijících v okolí (kapitola 7). V okolí spaloven byla rovněž pozorována kontaminace půdy toxickými látkami (především dioxiny) a s ní související kontaminace domácích chovů slepic anebo dobytka. Už jen jejich výzkum představoval další vyvolané náklady (kapitoly 3.4 a 9.5). Byť o některých jejich vlivech na životní prostředí můžeme stále diskutovat, protože nebyly jednoznačně prokázány, spalovny odpadů představují zastaralý, neudržitelný a drahý způsob nakládání s odpady, který má negativní dopady na životní prostředí, lidské zdraví, a dokonce celý planetární ekosystém. Moderní spalovny se snaží zařadit do systému cirkulární ekonomiky, a proto hledají cesty využití popela, kterého ze spáleného odpadu zbývá až jedna třetina z jeho původní hmotnosti (kapitola 3.3.3). I v tomto ohledu už například předimenzované nizozemské spalovny narazily na pomyslný strop a nositel Nobelovy ceny Ernst Worrell proto označil nizozemské silnice budované ze spalovnového popela za „lineární skládky“ (kapitola 3.3.3.1). Spalování odpadů, i když produkuje energii, která pohání náš moderní, energeticky náročný život, také aktivně přispívá k cyklu změny klimatu. Emise oxidu uhličitého, vzniklého procesem spalování, jsou považovány za jednu z hnacích sil skleníkového efektu, který má vážné důsledky ve formě globálního oteplování a změny klimatu. Do roku 2050 povede přeměna plastového odpadu na energii (včetně spalování v ZEVO) k větším emisím oxidu uhličitého než spalování fosilních paliv. Energetické využití odpadu tedy nepomáhá řešit globální změnu klimatu, ale přispívá k ní a představuje tak slepou uličku v nahrazování uhlí (kapitola 4.1). Zatímco se zdá, že odpad kouzelně mizí, skutečnost je taková, že spalováním odpadu ničíme cenné suroviny, které už nemáme možnost znovu využít, recyklovat nebo kompostovat, zatímco nepoužitelná třetina původní hmotnosti odpadů zůstává obohacena o toxické látky. Provozem spaloven podporujeme lineární odpadové hospodářství, které vyžaduje neustálý přísun odpadu.
... The previous studies have found that living within 3 kilometers from an incinerator plant indicates an increased risk of lymphoma and soft tissue sarcoma cancer up to 3.5% . More evidence is shown that living close to an incinerator has relation to respiratory disease [3][4]. In particular the incinerator related workers were exposed to particulates and heavy metals 10 to 100 folds greater than that of general population [5]. ...
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This study aimed to assess the health risk associated with the inhalation of air pollutants including VOCs and heavy metals for workers at waste incinerator site in the South of Thailand. Air samples were collected and analyzed followed by NIOSH standard method, air samples were collected for 8 hours continuously. The concentration of heavy metal; Hg, Cd, Pb, Mn, Ni were very low while mean concentrations of VOCs; benzene, toluene, ethylbenzene, xylenes, and styrene were determined as 0.080, <0.001, 0.031, 0.043, and <0.001 mg/m 3 respectively. Health risk assessment was employed to evaluate the carcinogenic and non-carcinogenic effects. The cancer risk for benzene exposure was estimated to be 1.26 x 10-5 that is higher than the acceptable risk level of 1 x 10-6. Non-carcinogenic risk (Hazard Quotients; HQ) for toluene, ethylbenzene, xylenes and styrene was at acceptable level. Thus, workers in this plant were at risk to health effects associated with benzene via inhalation exposure. Health promotion and risk communication should be given to them in appropriated way.
... 13 This study is also slightly similar to a referenced research done in Japan which focuses on the relationship between the prevalence of allergic disorders and the distance of schools from the incineration plant. 14 The research found that schools closer to the nearest municipal waste incineration plants were found to have increased prevalence of respiratory disorders but there was no evident relationship between distance of schools from incineration plants and prevalence of atopic dermatitis. 14 It is somewhat surprising that only 45% of Igando respondents reported common cold as a symptom of a respiratory disorder whilst 50% of Badagry respondents reported it. ...
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... Porta et al. [8], meanwhile, concluded that the association between incinerators and respiratory symptoms was inconclusive considering the uncertainty and residual confounding. Unlike the authors of other studies, Miyake et al. [30] suggested that the proximity of schools to municipal waste incinerators may be associated with an increased prevalence of wheezing, with an adjusted odds ratio of 1.08 (95% CI: 1.01-1.15). From the literature review, the association between the proximity to incinerators and respiratory symptoms was inconclusive. ...
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Background Systematic international comparisons of the prevalences of asthma and other allergic disorders in children are needed for better understanding of their global epidemiology, to generate new hypotheses, and to assess existing hypotheses of possible causes. We investigated worldwide prevalence of asthma, allergic rhinoconjunctivitis, and atopic. Methods We studied 463 801 children aged 13–14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304 796 children. Findings We found differences of between 20-fold and 60-fold between centres in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema, with four-fold to 12-fold variations between the 10th and 90th percentiles for the different disorders. For asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia. For allergic rhinoconjunctivitis, the centres with the highest prevalences were scattered across the world. The centres with the lowest prevalences were similar to those for asthma symptoms. For atopic eczema, the highest prevalences came from scattered centres, including some from Scandinavia and Africa that were not among centres with the highest asthma prevalences; the lowest prevalence rates of atopic eczema were similar in centres, as for asthma symptoms. Interpretation The variation in the prevalences of asthma, allergic rhinoconjunctivitis, and atopic-eczema symptoms is striking between different centres throughout the world. These findings will form the basis of further studies to investigate factors that potentially lead to these international patterns.
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In two regions of Sydney where sewage treatment facilities with high temperature sludge burning incinerators are installed, there was concern that the resultant emissions were causing a local increase in symptoms of asthma and other allergic diseases. To investigate whether living in a region with high temperature sludge burning incinerators was associated with an increased prevalence of childhood asthma or allergy. We studied 713 children aged eight-12 years in two regions close to incinerators and 626 children in a control region with no sludge burning incinerator. We measured respiratory illness in the previous year by questionnaire, airway hyper-responsiveness (AHR) by histamine inhalation test, and atopy by skin prick tests. 'Current asthma' was defined as AHR and recent wheeze. Recordings of oxides of nitrogen and sulphur, hydrogen sulphide, ozone and particulates during the study period showed that the level of pollutants did not vary in any major way between the study regions and the control region. The prevalence of current asthma, atopy, symptom frequency or any category of severity of asthma illness was not significantly different between the control and study regions. This suggests that factors other than intermittent or industrial air pollutants are responsible for the high prevalence of asthma symptoms, asthma medication use, asthma morbidity and AHR in the study of children.
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In all, 70 municipal incinerators, 307 hospital incinerators and 460 toxic-waste landfill sites in Great Britain were examined for evidence of effluents causing childhood cancers. Municipal incinerators had previously shown significant excesses of adult cancers within 7.5 and 3.0 km. The relative risks for adults had been marginal and an analysis of childhood cancers seemed to offer a more sensitive approach. A newly developed technique of analysis compares distances from suspect sources to the birth addresses and to the death addresses of cancer-children who had moved house. A localized hazard, effective at only one of these times, must be preferentially associated with the corresponding address. This creates an asymmetry of migrations towards or away from age-restricted effective sources. The child-cancer/leukaemia data showed no systematic migration-asymmetries around toxic-waste landfill sites; but showed highly significant excesses of migrations away from birthplaces close to municipal incinerators. Relative risks within 5.0 km of these sites were about 2:1. Hospital incinerators gave analogous results. The ratios greatly exceed findings around 'non-combustion' urban sites. Because of their locations, the specific effects of the municipal incinerators could not be separated clearly from those of adjacent industrial sources of combustion-effluents. Both were probably carcinogenic. Landfill waste sites showed no such effect.
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In order to evaluate the characteristics of fatigue symptoms and their association with the life style and the health status, we examined using data accumulated by the longitudinal surveys from 1992 to 1998, in 118 six-year primary school children and 129 second-year junior high school children. The complaints of "drowsiness and dullness", such as "become drowsy" (71%), "give a yawn" (59%) and "want to lie down" (51%), respectively, were most frequently observed. The proportion of these complaints was high before the first morning class, but decreased when the children leave school. Notably, the complaints of "difficulty in concentration" annually have increased. Children with undesirable eating habits, particularly those who often eat salty foods, or poor life style, such as staying up late at night tended to have more complaints of fatigue symptoms. By correlation analysis, these complaints were significantly related to the obesity degree, blood pressure, HDL cholesterol and atherogenic index. These results support the hypothesis that fatigue symptoms increase or are associated with life style and health status. Consequently, it is necessary to improve the life style such as dietary habits and rhythm of life for the reduction of fatigue symptom.