Chagas cardiomyopathy and ischemic stroke

ArticleinExpert Review of Cardiovascular Therapy 4(1):119-30 · February 2006with11 Reads
DOI: 10.1586/14779072.4.1.119 · Source: PubMed


    American trypanosomiasis, known as Chagas disease is a major cause of cardiomyopathy in South America. Irreversible damage to the heart can appear 10-20 years after chagasic infection. The relationship between Chagas cardiomyopathy and ischemic stroke has been reviewed. Significant variables that predict ischemic stroke in chagasic patients have been identified: apical aneurysm, cardiac insufficiency, electrocardiogram arrhythmia and female gender. Chagasic cardiomyopathy should be included in the differential diagnosis of the etiology of stroke, being a potential source of cardioembolic stroke.