Article

Synthesis and Screening of Bicyclic Carbohydrate-Based Compounds: A Novel Type of Antivirals

Department of Organic Chemistry, Ghent University, Gand, Flemish, Belgium
Bioorganic & Medicinal Chemistry Letters (Impact Factor: 2.42). 04/2006; 16(6):1495-8. DOI: 10.1016/j.bmcl.2005.12.048
Source: PubMed

ABSTRACT

A small library of bicyclic carbohydrate derivatives was synthesized and screened. A strong and selective activity against cytomegalovirus was found. Structure-activity relationship for this new type of antivirals is discussed.

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