Reliability and validity of the Beck Depression Inventory in patients with Parkinson's disease

Leiden University, Leyden, South Holland, Netherlands
Movement Disorders (Impact Factor: 5.68). 05/2006; 21(5):668-72. DOI: 10.1002/mds.20792
Source: PubMed


We evaluated the validity, reliability, and potential responsiveness of the Beck Depression Inventory (BDI) in patients with Parkinson's disease (PD). In part 1 of the study, 92 patients with PD underwent a structured clinical interview for DSM major depression and based on this patients were considered depressed (PD-D) or nondepressed (PD-ND). Subsequently, patients filled in the BDI. In part 2, a postal survey consisting the BDI was performed in 185 PD patients and 112 controls. Test-retest reliability was assessed in 60 PD patients. The factor analysis revealed a cognitive-affective and a somatic factor. Cronbachs alpha for the BDI was 0.88. Mean BDI indicated significant differences (P<0.001) between the PD and control group, between the PD-ND and PD-D group, and between PD-ND and control group. In part 1, the receiver operating characteristic curves showed that the area under the curve for the total BDI was 0.88. A cutoff was calculated for the BDI (14/15) that had the highest sum of sensitivity (0.71) and specificity (0.90). In part 2, the test-retest reliability for the BDI total score was 0.89 (intraclass correlation coefficient). The smallest real difference was 3.3 for the total BDI. The BDI is a valid, reliable, and potential responsive instrument to assess the severity of depression in PD. However, an adjusted cutoff is recommended.

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Available from: Johan Marinus
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    • "The Beck Depression Inventory (Beck et al., 1961; Visser et al., 2006) and the Apathy Evaluation Scale—Patient Version (Marin Leentjens et al., 2008) were also administered to assess severity of depression and apathy, respectively. The neuropsychological assessment and the administration of self-report questionnaires was carried out on two different days over a one-week period. "
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    ABSTRACT: Prospective memory (PM), that is, the ability to keep in memory and carry out intentions in the future, is reported to be impaired in individuals with Parkinson's disease (PD). PM failure may be also associated with reduced daily living functioning in these patients. Little is known, however, about the relationship between mild cognitive impairment (MCI) and time-based PM functioning in PD patients and the possible impact of PM deficits on patients' autonomy in daily living. Here we aimed to investigate whether MCI associated with PD affects time-based PM. We also wished to determine whether PM impairment accounts for reduced autonomous management of medication in these patients. The study included 48 PD patients with MCI, 33 PD patients without cognitive disorders (PDN) and 20 healthy controls. The time-based PM procedure required that subjects perform an action after a fixed time. The PM procedure was incorporated in the standard neuropsychological assessment. One score was computed for the ability to retrieve the intention (prospective component) and one for remembering the action to be executed (retrospective component). The Pill Questionnaire was administered to assess the ability to manage medication. PD patients with MCI performed less accurately in the PM procedure than HC and tended to perform poorer than PDN. Moreover, in PD patients with MCI, accuracy on the prospective component of the PM task and performance on the Modified Card Sorting Test significantly predicted the ability to manage medication. RESULTS document that reduced efficiency of time-based PM processes in PD is specifically related to the presence of MCI. The same data indicate that PM weakness may be associated with impaired daily living functioning and decreased autonomy.
    Full-text · Article · Jun 2015 · Frontiers in Human Neuroscience
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    • "To minimize inter-rater variability, only three clinically experienced raters were used for these tests at all visits. During the baseline visit and at the 48-week visit, participants filled out the PDQ-39 questionnaire [25], which is a disease-specific measure of subjective health status, and the Beck Depression Inventory [26], an instrument to assess the severity of depression. In addition, at the baseline visit participants completed a brief demographic survey, and at week 48, participants filled out a brief post-exercise program survey. "
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    Full-text · Article · Oct 2013 · Parkinsonism & Related Disorders
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    • "Previous findings in PD patients have shown an association between on/off states, fluctuations of mood and anxiety symptoms [47], and a potential negative influence of affective disorders on cognitive performance [48] [49]. Therefore, the State and Trait Anxiety Inventory-State Anxiety (STAY-S) [50] and the Beck Depression Inventory (BDI) [51] [52] were administered to both PD and healthy participants in the two experimental sessions. "
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