Article

Reliability and validity of the Beck Depression Inventory in patients with Parkinson's disease

Leiden University, Leyden, South Holland, Netherlands
Movement Disorders (Impact Factor: 5.68). 05/2006; 21(5):668-72. DOI: 10.1002/mds.20792
Source: PubMed

ABSTRACT

We evaluated the validity, reliability, and potential responsiveness of the Beck Depression Inventory (BDI) in patients with Parkinson's disease (PD). In part 1 of the study, 92 patients with PD underwent a structured clinical interview for DSM major depression and based on this patients were considered depressed (PD-D) or nondepressed (PD-ND). Subsequently, patients filled in the BDI. In part 2, a postal survey consisting the BDI was performed in 185 PD patients and 112 controls. Test-retest reliability was assessed in 60 PD patients. The factor analysis revealed a cognitive-affective and a somatic factor. Cronbachs alpha for the BDI was 0.88. Mean BDI indicated significant differences (P<0.001) between the PD and control group, between the PD-ND and PD-D group, and between PD-ND and control group. In part 1, the receiver operating characteristic curves showed that the area under the curve for the total BDI was 0.88. A cutoff was calculated for the BDI (14/15) that had the highest sum of sensitivity (0.71) and specificity (0.90). In part 2, the test-retest reliability for the BDI total score was 0.89 (intraclass correlation coefficient). The smallest real difference was 3.3 for the total BDI. The BDI is a valid, reliable, and potential responsive instrument to assess the severity of depression in PD. However, an adjusted cutoff is recommended.

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    • "The Beck Depression Inventory (Beck et al., 1961; Visser et al., 2006) and the Apathy Evaluation Scale—Patient Version (Marin Leentjens et al., 2008) were also administered to assess severity of depression and apathy, respectively. The neuropsychological assessment and the administration of self-report questionnaires was carried out on two different days over a one-week period. "
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    • "To minimize inter-rater variability, only three clinically experienced raters were used for these tests at all visits. During the baseline visit and at the 48-week visit, participants filled out the PDQ-39 questionnaire [25], which is a disease-specific measure of subjective health status, and the Beck Depression Inventory [26], an instrument to assess the severity of depression. In addition, at the baseline visit participants completed a brief demographic survey, and at week 48, participants filled out a brief post-exercise program survey. "
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