“Financial Ties Between DSM-IV Panel Members and the Pharmaceutical Industry,”

University of Massachusetts, Boston, USA.
Psychotherapy and Psychosomatics (Impact Factor: 9.2). 02/2006; 75(3):154-60. DOI: 10.1159/000091772
Source: PubMed


Increasing attention has been given to the transparency of potential conflicts of interest in clinical medicine and biomedical sciences, particularly in journal publishing and science advisory panels. The authors examined the degree and type of financial ties to the pharmaceutical industry of panel members responsible for revisions of the Diagnostic and Statistical Manual of Mental Disorders(DSM).
By using multimodal screening techniques the authors investigated the financial ties to the pharmaceutical industry of 170 panel members who contributed to the diagnostic criteria produced for the DSM-IV and the DSM-IV-TR.
Of the 170 DSM panel members 95 (56%) had one or more financial associations with companies in the pharmaceutical industry. One hundred percent of the members of the panels on 'Mood Disorders' and 'Schizophrenia and Other Psychotic Disorders' had financial ties to drug companies. The leading categories of financial interest held by panel members were research funding (42%), consultancies (22%) and speakers bureau (16%).
Our inquiry into the relationships between DSM panel members and the pharmaceutical industry demonstrates that there are strong financial ties between the industry and those who are responsible for developing and modifying the diagnostic criteria for mental illness. The connections are especially strong in those diagnostic areas where drugs are the first line of treatment for mental disorders. Full disclosure by DSM panel members of their financial relationships with for-profit entities that manufacture drugs used in the treatment of mental illness is recommended.

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    • "The DSM's classification of illnesses has financial impact for both pharmaceutical companies and association members. Nearly 70 percent of the members of the task force charged with assembling the next version of the Diagnostic and Statistical Manual, the DSM–5, have financial relationships with pharmaceutical companies, up from 57 percent for the previous version (Cosgrove, Krimsky, Vijayaraghavan, and Schneider, 2006; PLoS Medicine Editors, 2012). "
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    • "This practice may foster an agenda where pharmaceutical companies write scientific articles in order to promote a certain drug treatment for a medical condition. In recent years it has also been revealed that members of the panels for DSM-IV and DSM-5 have financial ties to the pharmaceutical industry [76]–[77]. There is also the issue of non-publication of trials or exclusion of relevant data from published trials, risks leading to inaccurate recommendations for treatment [78]. "
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    • "many journals do not include disclosure statements in their articles or have only started recently, response rates in surveys were often low, and authors often do not to disclose conflicts in their scientific publications [26,27]. A few studies have used other sources such as US patent databases [22,28]. "
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