Bartonella Spp. in Pets and Effect on Human Health

Department of Population Health and Reproduction, University of California School of Veterinary Medicine, Davis, California 95616, USA.
Emerging infectious diseases (Impact Factor: 6.75). 04/2006; 12(3):389-94. DOI: 10.3201/eid1205.050931
Source: PubMed


Among the many mammals infected with Bartonella spp., pets represent a large reservoir for human infection because most Bartonella spp. infecting them are zoonotic. Cats are the main reservoir for Bartonella henselae, B. clarridgeiae, and B. koehlerae. Dogs can be infected with B. vinsonii subsp. berkhoffii, B. henselae, B. clarridgeiae, B. washoensis, B. elizabethae, and B. quintana. The role of dogs as an important reservoir of Bartonella spp. is less clear than for cats because domestic dogs are more likely to be accidental hosts, at least in nontropical regions. Nevertheless, dogs are excellent sentinels for human infections because a similar disease spectrum develops in dogs. Transmission of B. henselae by cat fleas is better understood, although new potential vectors (ticks and biting flies) have been identified. We review current knowledge on the etiologic agents, clinical features, and epidemiologic characteristics of these emerging zoonoses.

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Available from: Bruno Chomel
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    • "These fleas are common on dogs and can also feed on humans; therefore, this genus may be considered an important vector of Bartonella spp., and dogs would be a potential source of this zoonotic agent to humans (Yore et al. 2014). Two C. felis pools from cats were positive for B. henselae or B. clarridgeiae , which are frequently associated with feline hosts, but can be transmitted to dogs and humans (Chomel et al. 2006). "
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    ABSTRACT: The bacterial genus Bartonella includes several species with zoonotic potential, some of which are common in domestic dogs and cats, as well as in their fleas. Because there is no previous information about the presence of Bartonella species in fleas from Central America, this study aimed at evaluating the presence of Bartonella spp. in fleas collected from dogs and cats in Costa Rica. A total 72 pools of Ctenocephalides felis and 21 pools of Pulex simulans were screened by conventional PCR to detect Bartonella DNA fragments of the citrate synthase (gltA) and the β subunit RNA polymerase (rpoB) genes. Three (4.2%) pools of C. felis and five pools (22.7%) of P. simulans were found positive for Bartonella DNA. Sequences corresponding to Bartonella vinsonii subsp. berkhoffii strain Winnie, B. rochalimae, and an undescribed Bartonella sp. (clone BR10) were detected in flea pools from dogs, whereas Bartonella henselae and B. clarridgeiae sequences were identified in flea pools from cats. The detection of zoonotic Bartonella spp. in this study should increase the awareness to these flea-borne diseases among physicians and public health workers and highlight the importance of flea control in the region.
    Full-text · Article · Sep 2015 · Vector borne and zoonotic diseases (Larchmont, N.Y.)
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    • "including Bartonella rochalimae, Bartonella koehlerae, Bartonella bovis, and Bartonella quintana (Kordick et al. 1999, Sander et al. 1999, Breitschwerdt 2008, Kaiser et al. 2011). Domestic dogs are believed to be one of the reservoirs for Bartonella vinsonii subspecies berkhoffii (Breitschwerdt et al. 2010, Diniz et al. 2013, Chomel et al. 2014) and can also be infected with B. henselae, B. clarridgeiae, and B. rochalimae, like domestic cats (Mexas et al. 2002; Chomel et al. 2006, 2014; Kaiser et al. 2011; Brenner et al. 2013). "
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    ABSTRACT: In the present study, we investigated 238 fleas collected from cats and dogs in three regions of Peru (Ancash, Cajamarca, and Lima) for the presence of Bartonella DNA. Bartonella spp. were detected by amplification of the citrate synthase gene (16.4%) and the 16S-23S intergenic spacer region (20.6%). Bartonella rochalimae was the most common species detected followed by Bartonella clarridgeiae and Bartonella henselae. Our results demonstrate that dogs and cats in Peru are infested with fleas harboring zoonotic Bartonella spp. and these infected fleas could pose a disease risk for humans.
    Full-text · Article · Sep 2015 · Journal of Medical Entomology
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    • "The prevalence of infection varies depending on the geographic region, from a low prevalence (Norway 0%) in regions with a cold climate to high values of prevalence in regions with a hot and humid climate (Philippines 68%)[3,4]. It was also observed that seroprevalence varies depending on the population of cats, dependent on whether they are stray or pet animals[4]. Due to the high prevalence of B. henselae infection in cats, it was diffi cult to correlate this infection with clinical signs[5]. "
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    ABSTRACT: The aim of this study was to determine the prevalence of coinfection with pathogens Bartonella henselae, feline immunodeficiency virus, and feline leukemia virus in stray cats from the area of Novi Sad and Belgrade, Serbia. Each of 60 individual cats was clinically examined and the blood sampled. Therewithal an epidemiological survey was made. Blood sera were separated by centrifugation and serologically tested in order to determine the presence of Bartonella henselae specific antibodies (by direct immunofluorescence assay), feline immunodeficiency virus specific antibodies (by rapid test SNAP Combo) and feline leukemia virus antigens (by rapid test SNAP Combo). Of the 60 cat sera, serologically examined using IFA test, 33 (55%) were positive for the presence of IgG specifi c to B. henselae antigens. A total of 13 (27%) of the 60 tested cat sera were positive for the presence of specific antibodies to FIV antigens. None of the 60 tested cat sera were positive for the presence of FeLV antigen. Of the 33 cat sera which contained IgG antibodies to B. henselae, 6 cat sera also gave a positive reaction to the presence of specific IgG antibodies to FIV; this was a coinfection seroprevalence of 10% in the total population of studied cats. The results obtained in this study indicate the presence of B. henselae and FIV coinfection in cats from Serbia, without FeLV positive cats. An increase in the manifestations of clinical symptoms in cats in which the serological tests determined coinfection with B. henselae and FIV is evident compared to those seropositive only to B. henselae.
    Full-text · Article · Sep 2014
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