Bone marrow aspiration before bone marrow core biopsy using the same bone marrow biopsy needle: A good or bad practice?

Division of Haematology/Oncology, Department of Medicine, Buffalo General Hospital, NY 14203, USA.
Journal of Clinical Pathology (Impact Factor: 2.92). 03/2007; 60(2):212-5. DOI: 10.1136/jcp.2006.037341
Source: PubMed


A single-needle single-site technique for bone marrow aspiration and core biopsy has been compared with a two-needle technique, using 30 randomly selected patients who required these two investigations. In addition, two single-needle techniques were compared, aspirating immediately after penetrating the cortex or, alternatively, aspirating after the needle (without the stilette) had been advanced 20-25 mm. The two-needle technique was found to be superior to either of the single-needle techniques, which often resulted in a biopsy specimen that was denuded of bone marrow cells.

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