A Prospective Study of Risk Factors for Erectile Dysfunction

ArticleinThe Journal of Urology 176(1):217-21 · August 2006with24 Reads
DOI: 10.1016/S0022-5347(06)00589-1 · Source: PubMed
We examined the impact of obesity, physical activity, alcohol use and smoking on the development of erectile dysfunction. Subjects included 22,086 United States men 40 to 75 years old in the Health Professionals Followup Study cohort who were asked to rate their erectile function for multiple periods on a questionnaire mailed in 2000. Men who reported good or very good erectile function and no major chronic disease before 1986 were included in the analyses. Of men who were healthy and had good or very good erectile function before 1986, 17.7% reported incident erectile dysfunction during the 14-year followup. Obesity (multivariate relative risk 1.9, 95% CI 1.6-2.2 compared to men of ideal weight in 1986) and smoking (RR 1.5, 95% CI 1.3-1.7) in 1986 were associated with an increased risk of erectile dysfunction, while physical activity (RR 0.7, 95% CI 0.7-0.8 comparing highest to lowest quintile of physical activity) was associated with a decreased risk of erectile dysfunction. For men in whom prostate cancer developed during followup, smoking (RR 1.4, 95% CI 1.0-1.9) was the only lifestyle factor associated with erectile dysfunction. Reducing the risk of erectile dysfunction may be a useful and to this point unexploited motivation for men to engage in health promoting behaviors. We found that obesity and smoking were positively associated, and physical activity was inversely associated with the risk of erectile dysfunction developing.
    • "Typically when exploring sexual performance, it is done in the context of exploring sexual dysfunction (Bacon, Mittleman, Kawachi, Glasser, & Rimm, 2006; Dabrowska, Drosdzol, Skrzypulec and Plinta 2010). Researchers and clinicians tend to examine issues at the points along the stages of sexual response (Kaplan, 1979; Masters & Johnson, 1966). "
    [Show abstract] [Hide abstract] ABSTRACT: The purpose of the study was to examine the relationship between exercise and sexual performance indicators among healthy adults. The sample consisted of 509 participants ranging in ages from 18-74 who completed a 30-item questionnaire on exercise frequency, intensity, time, and type and sexual performance indicators. Exercise was measured using the FITT principle of frequency, intensity, time, and type. Sexual performance indicators were identified as frequency of sexual arousal, ability to be easily aroused, number of orgasms in a single sexual episode, ease of orgasm, frequency of sexual intercourse, and sexual arousal then loss of interest. Spearman’s rho correlations demonstrated numerous significant relationships between the exercise FITT principle and the sexual performance indicators. Analysis of the FITT principle revealed that aerobic frequency was positively correlated with more of the sexual performance indicators compared to any of the other variables associated with frequency, intensity, time, or type of exercise; while intensity of strength training had the strongest positive correlation with three of the sexual performance indicators.
    Full-text · Article · Dec 2015 · Andrologia
    • "(2013) 13 found a positive association with ED and suggested that this occurs due to the fact that alcohol reduces plasma testosterone and increases serum estrogen, which may harm the erectile function in the long term 52 . According to Bacon et al. (2006) 38 , these data are important to motivate individuals to adopt a healthier lifestyle, including physical activity and a balanced diet, thus avoiding an immediate problem. It should be emphasized that many men do not adopt such behavior as they argue that negative aspects for one's health and wellbeing only occur in older individuals 38 . "
    [Show abstract] [Hide abstract] ABSTRACT: Defined as the constant or recurrent inability to attain or maintain a satisfactory erection, erectile dysfunction (ED) has multifactorial causes. Regular physical activity can be used as a preventive tool for ED. In this sense, the main objective of this study was to analyze the scientific literature, published in the last ten years (2004-2014), about the relationship between physical activity, ED and the associated factors among men older than 17 years in cross-sectional studies, randomized clinical trials and cohort studies. A systematic review was performed in articles published in the Bireme, ScienceDirect, and PubMed/Medline databases, in the SciELO electronic library and in the Portal of the Coordination for the Improvement of Higher Education Personnel (CAPES) Journal and written in Portuguese, English and Spanish. A total of 230 studies were identified, and only 19 met the inclusion criteria, all of which were published in English. ED was diagnosed in all studies. Concerning physical activity, 17 studies identified a significant association with a lower incidence of ED, including cross-sectional and quasi-experimental studies and randomized clinical trials. ED appeared to be associated with different factors related to men’s lifestyle, particularly their level of education, non-communicable chronic diseases, body mass index and age.
    Full-text · Article · Jan 2015 · Andrologia
    • "The current literature has yet to reach a consensus as to the magnitude of the benefits for smoking cessation specifically with regard to ED. Indeed, in multiple cross-sectional studies, former smokers (defined as having quit smoking >1 year prior to the study) have an increased risk of suffering from any form of ED compared to men who have never smoked (Austoni et al., 2005; Gades et al., 2005; Bacon et al., 2006). Former smokers have also been shown to have increased risk compared to current smokers, even when adjusted for age (Ghalayini et al., 2010). "
    [Show abstract] [Hide abstract] ABSTRACT: Cigarette smoking is a leading cause of preventable morbidity and mortality in the United States. Although public policies have resulted in a decreased number of new smokers, smoking rates remain stubbornly high in certain demographics with 20% of all American middle-aged men smoking. In addition to the well-established harmful effects of smoking (i.e. coronary artery disease and lung cancer), the past three decades have led to a compendium of evidence being compiled into the development of a relationship between cigarette smoking and erectile dysfunction. The main physiologic mechanism that appears to be affected includes the nitric oxide signal transduction pathway. This review details the recent literature linking cigarette smoking to erectile dysfunction, epidemiological associations, dose dependency and the effects of smoking cessation on improving erectile quality.
    Full-text · Article · Dec 2014
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