The Availability of Web Sites Offering to Sell Opioid Medications Without Prescriptions

Medical Affairs Alkermes, Inc., 88 Sidney St., Cambridge, MA 02139, USA.
American Journal of Psychiatry (Impact Factor: 12.3). 08/2006; 163(7):1233-8. DOI: 10.1176/appi.ajp.163.7.1233
Source: PubMed


This study was designed to determine the availability of web sites offering to sell opioid medications without prescriptions.
Forty-seven Internet searches were conducted with a variety of opioid medication terms, including "codeine," "no prescription Vicodin," and "OxyContin." Two independent raters examined the links generated in each search and resolved any coding disagreements. The resulting links were coded as "no prescription web sites" (NPWs) if they offered to sell opioid medications without prescriptions.
In searches with terms such as "no prescription codeine" and "Vicodin," over 50% of the links obtained were coded as "NPWs." The proportion of links yielding NPWs was greater when the phrase "no prescription" was added to the opioid term. More than 300 opioid NPWs were identified and entered into a database.
Three national drug-use monitoring studies have cited significant increases in prescription opioid use over the past 5 years, particularly among young people. The emergence of NPWs introduces a new vector for unregulated access to opioids. Research is needed to determine the effect of NPWs on prescription opioid use initiation, misuse, and dependence.

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    • "Products are sold as intranasal spray but are more commonly injected subcutaneously by reconstituting the lyophilized powder (10, 20, 30, 40, 50 and 100 mg) with 2 ml of sterile water (Langan et al., 2010; Paurobally et al., 2011, 2013). Of public health concern is that these products are unregulated, untested, potentially adulterated, and sold without prescription (Evans-Brown et al., 2009; Gordon, Forman & Siatkowski, 2006; Knudsen, Kjergaard & Dalhoff, 2012; Langan et al., 2010; Mataix, 2012; McVeigh et al., 2012; Paurobally et al., 2013). Clinuvel Pharmaceuticals (2009) has warned consumers of counterfeit products using the names 'melanotan I and II'. "
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