Procedure guideline for SPECT/CT imaging 1.0

Vanderbilt University Medical Center, Nashville, Tennessee 37232-2675, USA.
Journal of Nuclear Medicine (Impact Factor: 6.16). 08/2006; 47(7):1227-34.
Source: PubMed


The purpose of this Procedure Guideline is to assist physicians in recommending, performing, interpreting, and reporting the results of SPECT/CT for imaging of adult and pediatric patients. II. BACKGROUND INFORMATION AND DEFINITIONS SPECT is a tomographic scintigraphic technique in which a computer-generated image of local radioactive tracer distribution in tissues is produced through the detection of single-photon emissions from radionuclides introduced into the body. CT is a tomographic imaging technique that uses an external x-ray source to produce 3-dimensional anatomic imagedata.ThefirstSPECT/CTsystemcombinedadualhead g-camera and an integrated x-ray transmission system mounted on the same gantry. The CT image is used for attenuation correction as well as anatomic imaging, and the

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    • "Further, the adoption of new dual imaging techniques should be paired with the introduction of imaging guidelines [49–52]. A first evaluation of the adherence to PET/CT guidelines has revealed surprisingly large deviations from guideline recommendations [53], which are related to deviations among guideline recommendations themselves and the lack of interest and knowledge in adopting standardised imaging protocols. "
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    ABSTRACT: Since the 1990s, hybrid imaging by means of software and hardware image fusion alike allows the intrinsic combination of functional and anatomical image information. This review summarises in three parts the state of the art of dual-technique imaging with a focus on clinical applications. We will attempt to highlight selected areas of potential improvement of combined imaging technologies and new applications. In this third part, we discuss briefly the origins of combined positron emission tomography (PET)/magnetic resonance imaging (MRI). Unlike PET/computed tomography (CT), PET/MRI started out from developments in small-animal imaging technology, and, therefore, we add a section on advances in dual- and multi-modality imaging technology for small animals. Finally, we highlight a number of important aspects beyond technology that should be addressed for a sustained future of hybrid imaging. In short, we predict that, within 10 years, we may see all existing multi-modality imaging systems in clinical routine, including PET/MRI. Despite the current lack of clinical evidence, integrated PET/MRI may become particularly important and clinically useful in improved therapy planning for neurodegenerative diseases and subsequent response assessment, as well as in complementary loco-regional oncology imaging. Although desirable, other combinations of imaging systems, such as single-photon emission computed tomography (SPECT)/MRI may be anticipated, but will first need to go through the process of viable clinical prototyping. In the interim, a combination of PET and ultrasound may become available. As exciting as these new possible triple-technique-imaging systems sound, we need to be aware that they have to be technologically feasible, applicable in clinical routine and cost-effective.
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    • "Correct shape and position of the contours should be reviewed prior to calculation of the corrected slices. In the case of SPECT- CT systems, the CT component of the scan can be used to perform the attenuation correction (Delbeke et al. 2006). "
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    ABSTRACT: These guidelines summarize the views of the European Association of Nuclear Medicine (EANM) Neuroimaging Committee (ENC). The purpose of the guidelines is to assist nuclear medicine practitioners in recommending, performing, interpreting, and reporting the results of brain tumor imaging using 18-fluoro-2-deoxyglucose-PET (FDG-PET) as well as radiolabeled amino acid analogues SPECT or PET. The aim is to help in achieving a high quality standard of such functional imaging procedures to increase their diagnostic impact in neuroonco­logical practice. The present document is largely based on the EANM guidelines that have been published for FDG-PET (Bartenstein et al. 2002) and labeled amino acid analogues imaging (Vander Borght et al. 2006). It also includes an update in the light of the advances in the PET technology and the introduction of hybrid PET-CT systems, which will be part of the updated guidelines for FDG-PET produced by the ENC. The information provided should be taken in the context of local conditions and regulations.
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