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Effect of Aromatherapy on Symptoms of Dysmenorrhea in College Students: A Randomized Placebo-Controlled Clinical Trial

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Abstract

The purpose of this study was to explore the effect of aromatherapy on menstrual cramps and symptoms of dysmenorrhea. The study was a randomized placebo-controlled trial. The subjects were 67 female college students who rated their menstrual cramps to be greater than 6 on a 10-point visual analogue scale, who had no systemic or reproductive diseases, and who did not use contraceptive drugs. Subjects were randomized into three groups: (1) an experimental group (n = 25) who received aromatherapy, (2) a placebo group (n = 20), and (3) a control group (n = 22). Aromatherapy was applied topically to the experimental group in the form of an abdominal massage using two drops of lavender (Lavandula officinalis), one drop of clary sage (Salvia sclarea), and one drop of rose (Rosa centifolia) in 5 cc of almond oil. The placebo group received the same treatment but with almond oil only, and the control group received no treatment. The menstrual cramps levels was assessed using a visual analogue scale and severity of dysmenorrhea was measured with a verbal multidimensional scoring system. The menstrual cramps were significantly lowered in the aromatherapy group than in the other two groups at both post-test time points (first and second day of menstruation after treatment). From the multiple regression aromatherapy was found to be associated with the changes in menstrual cramp levels (first day: Beta = -2.48, 95% CI: -3.68 to -1.29, p < 0.001; second day: Beta = -1.97, 95% CI: -3.66 to -0.29, p = 0.02 and the severity of dysmenorrhea (first day: Beta = 0.31, 95% CI: 0.05 to 0.57, p = 0.02; second day: Beta = 0.33, 95% CI: 0.10 to 0.56, p = 0.006) than that found in the other two groups. These findings suggest that aromatherapy using topically applied lavender, clary sage, and rose is effective in decreasing the severity of menstrual cramps. Aromatherapy can be offered as part of the nursing care to women experiencing menstrual cramps or dysmenorrhea.
THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
Volume 12, Number 6, 2006, pp. 535–541
© Mary Ann Liebert, Inc.
Effect of Aromatherapy on Symptoms of
Dysmenorrhea in College Students:
A Randomized Placebo-Controlled Clinical Trial
SUN-HEE HAN, Ph.D., R.N.,
1
MYUNG-HAENG HUR, Ph.D., R.N.,
2
JANE BUCKLE, Ph.D., R.N,
3
JEEYAE CHOI, D.N.Sc., R.N.,
4
and MYEONG SOO LEE, Ph.D.
5
ABSTRACT
Objective: The purpose of this study was to explore the effect of aromatherapy on menstrual cramps and
symptoms of dysmenorrhea.
Design: The study was a randomized placebo-controlled trial.
Subjects: The subjects were 67 female college students who rated their menstrual cramps to be greater than
6 on a 10-point visual analogue scale, who had no systemic or reproductive diseases, and who did not use con-
traceptive drugs.
Intervention: Subjects were randomized into three groups: (1) an experimental group (n 25) who received
aromatherapy, (2) a placebo group (n 20), and (3) a control group (n 22). Aromatherapy was applied top-
ically to the experimental group in the form of an abdominal massage using two drops of lavender (Lavandula
officinalis), one drop of clary sage (Salvia sclarea), and one drop of rose (Rosa centifolia) in 5 cc of almond
oil. The placebo group received the same treatment but with almond oil only, and the control group received
no treatment.
Outcome measures: The menstrual cramps levels was assessed using a visual analogue scale and severity
of dysmenorrhea was measured with a verbal multidimensional scoring system.
Results: The menstrual cramps were significantly lowered in the aromatherapy group than in the other two
groups at both post-test time points (first and second day of menstruation after treatment). From the multiple
regression aromatherapy was found to be associated with the changes in menstrual cramp levels (first day:
Beta 2.48, 95% CI: 3.68 to 1.29, p 0.001; second day: Beta 1.97, 95% CI: 3.66 to 0.29,
p 0.02 and the severity of dysmenorrhea (first day: Beta 0.31, 95% CI: 0.05 to 0.57, p 0.02; second day:
Beta 0.33, 95% CI: 0.10 to 0.56, p 0.006) than that found in the other two groups.
Conclusions: These findings suggest that aromatherapy using topically applied lavender, clary sage, and rose
is effective in decreasing the severity of menstrual cramps. Aromatherapy can be offered as part of the nurs-
ing care to women experiencing menstrual cramps or dysmenorrhea.
535
1
School of Nursing, Wonkwang Public Health College, Iksan, Korea.
2
School of Nursing, Eulji University, Daejeon, South Korea.
3
Center for Complementary Medicine & Integrative Health, Faculty of Health and Human Science, Thames Valley University, Lon-
don, United Kingdom.
4
Clinical Informatician, Department of Professional Development, Spaulding Rehabilitation Hospital, Boston, MA.
5
Center for Integrative Medicine, Institute of Medical Science, Wonkwang University, Iksan, Korea.
Current address, Complementary Medicine, Peninsula Medical School, Universities of Exeter & Plymouth, Exeter, United Kingdom.
INTRODUCTION
D
ysmenorrhea is defined as painful menstruation in-
volving low abdominal pains (menstrual cramps),
which may be accompanied by other symptoms such as nau-
sea and fatigue. Menstrual cramps caused by dysmenorrhea
are a common problem. Some studies suggest that 50–93%
of women experience menstrual cramps caused by dysmen-
orrhea, and that 10–26% of women experience severe pain.
In a recent study in Korea, 83% of college women com-
plained of menstrual cramps, 18% rating their pain as very
severe.
1
In the most severe cases, the pain was rated 7.9 on
a 10-point visual analogue scale (VAS). However, despite
frequent occurrence and severity, menstrual cramps are not
acknowledged as a serious problem or one requiring nurs-
ing intervention. However, Milsom et al.
2
showed that the
intra-uterine pressure (IUP) of a patient with dysmenorrhea
was 55.3 3.8 mmHg in the relaxation phase and 175.0
6.1 mmHg in the contraction phase, and that the IUP dur-
ing contraction is greater than in labor.
1
Dysmenorrhea is usually treated with drugs, such as anal-
gesics, sedatives, antispasmodics, prostaglandin inhibitors,
uterine contraction inhibitors, nonsteroidal anti-inflammatory
drugs, vasopressin antagonists, and medication to stop ovu-
lation.
3
In a review article, Dawood
3
suggested that none of
these therapies are particularly effective but some may lead
to dependence or affect cognitive function. Bed rest, local heat
therapy, surgical intervention, and psychotherapy have also
been used.
3
In a 1999 survey, Han and Hur
1
found that the
most common methods to cope with menstrual cramps were
“endurance” and medication. Campbell and McGrath
4
found
that 70% of women with dysmenorrhea use medication. How-
ever, Chambers et al.
5
noted that the medication might not be
effective if not used regularly. Many studies suggest that men-
strual cramps and dysmenorrhea are not managed efficiently
despite their high occurrence and severity.
A variety of alternative methods have been used to treat
menstrual cramps. Some experimental studies have found
alternative methods such as acupuncture
6
and transcuta-
neous electrical nerve stimulation (TENS)
7
to be fairly ef-
fective (e.g., 50% reduction in pain). Kotani et al.
8
found
that the herbal medicine Toki-shakuyaku-san [Japanese an-
gelica root (Angelicae radix), peony root (Paeoniae radix),
Poria (Hoelen spp.), Chinese atractylodes rhizome (Atracty-
lodis lanceae rhizoma), Oriental water plantian rhizome
(Alismatis rhizome), Cnidium (cnidii rhizoma)] was more ef-
fective than placebo in treating primary dysmenorrhea. At-
tempting to cure idiopathic menstrual pain, Kim* used a
placebo in the form of a vitamin pill. Dawood and Ramos
9
suggested that concurrent use of TENS and ibuprofen might
be an effective treatment, and Harel et al.
10
used supple-
ments such as omega-3 fatty acids. TENS and ibuprofen to-
gether appear to be the most effective treatment for men-
strual cramps. Vance et al.
11
tried microwave diathermy, and
Kim et al.
12
tried biofeedback. However, many of these
treatments cannot be prescribed by nurses, and many con-
ventional drugs have side effects or their main effects do not
last long. Because dysmenorrhea is so common and has been
inadequately addressed, it is important to find an effective
method that can be easily used.
Aromatherapy is the therapeutic use of essential oils from
plants. Essential oils can be absorbed into the body via the
skin or the olfactory system. Aromatherapy is thought to be
particularly efficacious against menstrual cramps or dys-
menorrhea.
13–15
In some countries aromatherapy products
are sold and aromatherapy is used as a major complemen-
tary “caring” therapy.
16
Aromatherapy is perceived to be a
safe therapy.
17
Essential oils have been used for several hun-
dred years and are used regularly today by the public for
stress-management and for minor ailments.
18
However, the therapeutic effects of aromatherapy are not
well supported by clinical studies.
19
Keville and Green
20
sug-
gested that essential oils should be used for several days be-
fore dysmenorrhea or menstrual cramps are expected. They
recommend that the essential oils of chamomile (Chamomelum
nobile), clary sage (Salvia sclarea), lavender (Lavandula an-
gustifolia), marjoram (Origanum majorana), melissa (Melissa
officinalis), and geranium (Pelargonium graveolens) help in
treating menstrual cramps. Tisserand
15
suggested clary sage,
lavender, rose (Rosa centifolia), marjoram, geranium, and gin-
ger (Rhizoma zingiberis recens) as effective in treating dys-
menorrhea. Dye
13
suggested clary sage, chamomile, geranium,
and rose, while Baker
21
suggested geranium, Roman
chamomile, rosemary, lavender, clary sage, and sage.
The essential oil of lavender is thought to be an adreno-
cortical stimulant that stimulates menstruation and circula-
tion and has anticonvulsive properties. Lavabre
14
suggested
that lavender is also useful as a sedative and to alleviate
pain. Tisserand
15
suggested that clary sage has functions
similar to estrogen, such as normalizing the menstrual cy-
cle, promoting menstruation, and strengthening the uterus.
Tisserand
15
also suggested that rose has a great affinity for
the uterus and helps regulate the menstrual cycle and reduce
excessive bleeding. In this study, we hypothesized that ap-
plying these three essential oils together would provide a
synergistic blend that would have the highest chance of suc-
cess in treating the pain of menstrual cramps.
Different methods are used to deliver aromatherapy, such
as diffusers, baths, massage, and compresses. Massage is be-
lieved to be an effective way to improve blood and lymph
circulation and to reduce stress and ease stiff muscles. For
massage, the essential oil is diluted in a cold-pressed veg-
etable oil, a popular choice being sweet almond oil.
13,14,20
Massage appears to be a suitable method to deliver aro-
matherapy to treat menstrual cramps of dysmenorrhea.
The purpose of this study was to investigate whether the
combination of lavender, clary sage, and rose applied topically
alleviates menstrual cramps. If the results were positive, this
HAN ET AL.
536
*Kim G. The Effect of Menstrual Pain Relief by Placebo [un-
published Master’s thesis]. Pusan, Korea; Department of Nursing,
Pusan National University, 1985.
method of aromatherapy might be adopted as a nursing inter-
vention for patients with painful menstrual cramps.
MATERIALS AND METHODS
Design
The study consisted of a double-blind, three-group ex-
perimental pre-test/post-test design. Fifty-seven (57) partic-
ipants were randomly assigned to one of three groups. The
experimental group received aromatherapy in almond oil
with massage, the placebo group received treatment with al-
mond oil only and massage, and the control group received
no treatment.
The levels of dysmenorrhea and general and menstrual
characteristics were measured before the study began. After
the intervention, the levels of dysmenorrhea were measured
for each group on the first and second days of menstruation.
Subjects were told there were no side effects or contraindi-
cations to the treatment they were about to receive, but that,
in rare instances, skin irritation could occur. The study re-
ceived institutional approval from the Human Investigation
Ethics Committee and administrative approval from the Hu-
man Subjects Review Board of Wonkwang University Hos-
pital and School of Medicine before we approached the sub-
jects and obtained written consent from them.
Participants
The participants were college women enrolled in uni-
versities in Korea. A previous survey had identified 85
women who experienced dysmenorrhea. The selection cri-
teria were: (1) pain of menstrual cramps greater than 6
points on the 10-point VAS (a line calibrated from 0–10,
with 0 representing “no pain at all” and 10 representing
“pain as bad as it could be”); (2) no systemic disease or
disease of the genital organs; and (3) no use of contra-
ceptives. Participants who failed to meet all of these cri-
teria were excluded from the study. Patients with myoma
or fibrocystadenoma were also excluded from the study.
Of the 85 subjects who were originally screened, 67 en-
tered the initial phase of the study.
The experimental group (n 25; mean age, 20.6 1.27
years) received aromatherapy in almond oil with massage.
The placebo group (n 20; mean age, 20.9 1.93) re-
ceived treatment with almond oil only and massage, and the
control group (n 22; mean age, 20.5 0.51) received no
treatment. To randomize the study, each participant drew a
piece of paper with either A, B, or C written on it from a
closed box. When a participant drew A, she joined the ex-
perimental group; B, the placebo group; and C, the control
group. In discussing the nature of aromatherapy and the ex-
perimental procedures, the subjects were informed that they
would receive one of two types of aromatherapy, both of
which had the potential to relieve menstrual cramps. Sub-
jects were blinded as to whether they were receiving real or
sham aromatherapy, as were the clinical observers assess-
ing the endpoints. Four assistants contacted the subjects and
checked their responses.
Intervention
The experimental group received aromatherapy in the treat-
ment room every day beginning one week before the start of
menstruation and continuing until the first day of menstrua-
tion. The experimental and placebo groups received 15 min-
utes of aromatherapy or placebo, respectively. The aro-
matherapy was provided in the form of abdominal massage
with essential oils of lavender, clary sage, and rose in a 2:1:1
ratio, diluted in almond oil at a final concentration of 3%. The
treatment room for abdominal massage was isolated and
equipped with beds warmed by heating pads. Clients were re-
quested to lie on the bed and rest after the abdominal mas-
sage. The clients in the placebo group had the same treatment
with almond oil only. Each treatment lasted about 15 minutes
for both groups. No treatment was provided to the control
group, who continued their daily routine.
Each subject received a 15-minute abdominal massage
beginning with effleurage strokes in the shape of a flat di-
amond, working clockwise with a pressure of 4 on a scale
of 0–10, where 0 is no pressure and 10 is crushing pressure.
The masseur’s left hand was placed on the right hand and
both hands were placed on the right lower abdomen. The
stroke went to the ribs and then across the abdomen to the
left lower abdomen. This was followed by gentle kneading
at the left and right of the waist and then stroking across the
abdomen. Following this, the effleurage flat diamond stroke
began again. The strokes were slow, smooth, and continu-
ous. A cushion was placed under the subject’s knees to keep
the abdomen relaxed.
Data such as the severity of menstrual cramps and the
general and menstrual characteristics were collected from
all participants before the experiment and designated as pre-
test data. Data on the severity of menstrual cramps were col-
lected on the first and second days of menstruation after the
experimental treatment and designated as post-test data.
Measurement of menstrual cramps
The intensity of menstrual cramps was measured with a
10-point VAS, indicated by pointing to the appropriate value
on a 10-cm horizontal ruler. The intensity of pain was rated
to the first decimal place in centimeters. Higher scores re-
flected a greater severity of menstrual cramps.
Severity of dysmenorrhea
To measure the effect of dysmenorrhea on daily life, a
verbal multidimensional scoring system was applied as
used by Andersch and Milsom
22
and Sundell et al.
23
The
system uses four grades to indicate the extent to which
dysmenorrhea influences daily life. According to this scor-
ing system, mild dysmenorrhea is defined as menstruation
AROMATHERAPY MASSAGE EFFECT ON SYMPTOMS OF DYSMENORRHEA
537
that is painful but seldom inhibits the woman’s normal ac-
tivity and analgesics are seldom needed. Moderate dys-
menorrhea affects daily activities and requires analgesics,
but missing work or school is unusual. Severe dysmenor-
rhea clearly inhibits daily activity, is managed poorly by
analgesics, and has associated somatic symptoms such as
headache, tiredness, nausea, vomiting, or diarrhea. Symp-
toms were scored from 1 to 4 (1 none; 2 mild; 3 moder-
ate; 4 severe), according to the intensity experienced by
the subjects.
Data analysis
The data were analyzed using SigmaStat (Systat Software,
Richmond, CA) and SPSS software (SPSS, Chicago, IL).
Since the data were not normally distributed, the results are
presented as medians and interquartile ranges (IQRs). All out-
comes were compared using the nonparametric Mann-Whit-
ney rank test between groups and the Wilcoxon signed-rank
test across treatment times for each group.
Multiple regression analyses were used to estimate the ef-
fects and the validity of the hypothesis. We divided the analy-
ses into two parts, analyzing the first- and second-day results
with respect to baseline. In each of these analyses, the change
score (postintervention minus preintervention) was regressed
on the baseline score with two dummy-variable indicators:
one indicator was 1 for the placebo group and 0 otherwise,
and the other was 1 for the aromatherapy group and 0 other-
wise. The coefficients of these indicators therefore represent
placebo versus control and aromatherapy versus control com-
parisons. This procedure was performed separately for the
first- and second-day data.
The severity of dysmenorrhea in each woman was di-
chotomized into either 1, representing improvement (mean-
ing a strictly better postintervention score), or 0, represent-
ing no change or a lower postintervention score than
preintervention score. We then applied generalized multiple
linear regression modeling to this outcome.
RESULTS
The participants reported no side effects from the treat-
ment. The demographic characteristics of the participants
are listed in Table 1.
HAN ET AL.
538
T
ABLE
1. C
HARACTERISTICS OF
S
UBJECTS ON
A
ROMATHERAPY
, P
LACEBO
C
ONTROL
,
AND
N
O
-T
REATMENT
C
ONTROL
Aromatherapy Placebo No treatment
Characteristics (n 25) (n 20) (n 22)
Age (yr) 20.0 (20.0–21.0) 20.0 (20.0–21.0) 21.0 (20.0–21.0)
Age at menarche (yr) 13.5 (13.0–14.0) 13.0 (12.0–14.0) 13.0 (13.0–14.0)
Menstruation
Cycle (days) 28.0 (28.0–30.0) 30.0 (27.0–30.0) 30.0 (26.8–34.0)
Duration (days) 6.0 (5.0–7.0) 5.0 (5.0–6.8) 6.0 (5.0–6.5)
Amount
Profuse 7 (28.0%) 2 (10.0%) 4 (18.2%)
Moderate 16 (64.0%) 16 (80.0%) 14 (63.6%)
Scanty 2 (8.0%) 2 (10.0%) 4 (18.2%)
Pattern
Regular 17 (68.0%) 11 (55.0%) 10 (45.4%)
Irregular 8 (32.0%) 9 (45.0%) 12 (54.6%)
Use of analgesics
None 5 (20.0%) 4 (20.0%) 8 (36.4%)
Often 10 (40.0%) 12 (60.0%) 7 (31.8%)
Always 10 (40.0%) 4 (20.0%) 7 (31.8%)
Values are expressed as median (interquartile ranges).
T
ABLE
2. E
FFECTS OF
A
ROMATHERAPY ON
S
EVERITY OF
M
ENSTRUAL
C
RAMPS
Time Change
Group Preintervention First day Second day First day—pre Second day—pre
Aromatherapy 7.0 (6.5–8.3) 5.0 (3.0–6.0)**
,†‡
3.0 (1.0–5.0)**
,†‡
2.5 (5.0—1.5) 4.5 (5.0—2.0)
Placebo 7.0 (6.0–8.0) 7.0 (6.0–8.0) 7.0 (2.8–8.0)* 0.0 (0.0—1.0) 0.5 (5.0—1.0)
No treatment 7.5 (6.5–8.0) 7.0 (6.0–8.0) 7.0 (5.0–8.0) 0.0 (1.0—0.3) 0.0 (3.0—0.0)
Values are expressed as median (interquartile ranges).
*p 0.05; **p 0.001 by Wilcoxon signed rank test compared with baseline value;
p 0.01 by Mann-Whitney rank sum test
compared with the placebo;
p 0.01 compared to no treatment groups.
Table 2 lists the medians and IQRs for the levels of men-
strual cramps in the groups measured at three time points. The
severity was significantly lower in the aromatherapy group
than in the other two groups at both postintervention time
points (first and second days of menstruation after treatment).
Regression analyses were also applied to the changes in
severity at each day (postintervention minus preintervention)
using the baseline value, two indicators for aromatherapy, and
placebo compared to control. Aromatherapy was most strongly
associated with change in severity (Beta 2.48, 95% CI:
3.68 to 1.29, p 0.001), followed by the baseline value
of level of menstrual cramps (Beta 0.62, 95% CI: 0.99
to – 0.26, P 0.001), with the weakest association being with
placebo (Beta 0.42, 95% CI: 0.83 to 1.67, p 0.51) com-
pared to control for the first day. The trend was the same for
the second day. Aromatherapy was most strongly associated
with change in severity (Beta 1.97, 95% CI: 3.66 to
0.29, p 0.02), the baseline value of level of menstrual
cramps (Beta 0.52, 95% CI: – 1.04 to – 0.003, p 0.05),
and placebo (with the weakest association being with placebo
(Beta 0.27, 95% CI: 1.49 to 2.04, p 0.76) compared to
the control group).
Table 3 lists the severity of dysmenorrhea. We estimated
and tested the trends by applying multiple linear regression
modeling to the dichotomized severity of dysmenorrhea and
the dummy-variable indicators. The results demonstrated
that aromatherapy was associated with the change in sever-
ity (Beta 0.31, 95% CI: 0.05 to 0.57, p 0.02), the base-
line value of severity (Beta 0.21, 95% CI: 0.04 to 0.37,
p 0.02), and not for placebo (Beta 0.003, 95% CI:
–0.29 to 0.28, p 0.98) compared to controls for the first
day. The trend was the same for the second day. Aro-
matherapy was associated with the severity change (Beta
0.33, 95% CI: 0.10 to 0.56, p 0.006), the baseline value
of severity (Beta 0.33, 95% CI: 0.18 to 0.48, p 0.001),
and not for placebo (Beta 0.15, 95% CI: 0.40 to 0.10,
p 0.23) compared to controls.
DISCUSSION
One of the main goals of nursing is to enhance a patient’s
quality of life, which might include providing proper nursing
care for patients with menstrual cramps or dysmenorrhea. Be-
cause menstrual cramps and dysmenorrhea are personal top-
ics, women may suffer from these symptoms without seek-
ing help from a health care professional.
4,24,25
In some
extreme cases, the internal pressure from the uterine contrac-
tion during menstruation may be higher than that of labor.
22
The participants reported a serious level of discomfort before
the experimental treatment, as shown by the mean rating of
menstrual cramps of 7.18 1.37 on the 10-point VAS.
According to Sundell et al.
23
and Han and Hur,
1
greater
menstrual flow is associated with more severe pain. The
pretest data showed no differences in menstrual flow be-
tween the three groups. Han and Hur
1
showed that variables
such as age at menarche and the interval and duration of
menstruation are not related to menstrual cramps. These
variables did not differ significantly between groups and the
age at menarche differed by only 0.3 of a year.
In the experimental group, the abdominal massage was
given using 3% essential oils consisting of lavender, clary
sage, and rose (2:1:1 ratio) diluted in almond oil. Massage
is thought to enhance essential oil penetration into the skin.
The VAS was used to measure the effect of the experi-
mental treatment on menstrual cramps. Our results showed
that the levels of the menstrual cramps were reduced in the
experimental group more significantly compared with those
of other groups. In the experimental group, the menstrual
cramps on the first menstruation day decreased from 7.40
AROMATHERAPY MASSAGE EFFECT ON SYMPTOMS OF DYSMENORRHEA
539
T
ABLE
3. E
FFECT OF
A
ROMATHERAPY ON
S
EVERITY OF
D
YSMENORRHEA
Aromatherapy (n 25) Placebo (n 20) No treatment (n 22)
Severity of dysmenorrhea n (%) n (%) n (%)
Preintervention
10 (0.0) 0 (0.0) 1 (4.5)
22 (8.0) 4 (20.0) 7 (31.9)
3 21 (84.0) 12 (60.0) 13 (59.1)
42 (8.0) 4 (20.0) 1 (4.5)
First day
14 (16.0) 0 (0.0) 0 (0.0)
2 12 (48.0) 4 (20.0) 9 (40.9)
37 (28.0) 12 (60.0) 11 (50.0)
42 (8.0) 4 (20.0) 2 (9.1)
Second day
18 (32.0) 1 (5.0) 2 (9.1)
2 11 (44.0) 4 (20.0) 9 (40.9)
36 (24.0) 11 (55.0) 9 (40.9)
40 (0.0) 4 (20.0) 2 (9.1)
1, no dysmenorrhea; 2, mild dysmenorrhea; 3, moderate dysmenorrhea; 4, severe dysmenorrhea.
to 4.26 after aromatherapy. The change of the severity of
dysmenorrhea was significantly associated with aromather-
apy, suggesting that aromatherapy has an alleviating effect
on the severity of dysmenorrhea experienced during the first
few days of menstruation.
When the results of the study are compared with the out-
come of relaxation treatment to alleviate menstrual cramps via
biofeedback training, the reduction to 5.3 of menstrual treat-
ment is higher than that of bio-feedback.
12
In a study to ver-
ify the effects of herbal medicine on menstrual cramps, Kotani
et al.
8
reported a decrease in cramp severity from 6.2 to 4.4 on
the 10-point VAS scale after one menstrual cycle and to 3.2
after the second cycle. The effect of aromatherapy treatment
in our study produced a similar effect to those of the herbal
medicine TSS and TENS, which decreases the incidence of
sharp pains by 50%.
7
Although no other clinical studies have
been published on the effect of aromatherapy on menstrual
cramps, our data appear to support claims that aromatherapy
has beneficial effects in treating menstrual discomfort.
Menstrual cramps and dysmenorrhea are believed to be
“anemic pains” caused by reduced blood flow because of uter-
ine hyperactivity. The pain is associated with increased
prostaglandin and vasopressin production,
26,27
which causes
contraction and infarction of the endometrium. Menstrual
cramps and dysmenorrhea can occur when the menstrual flow
is constricted. Menstrual cramps are thought to be relieved by
increased blood circulation and antispasmodic and hormone-
regulatory drugs. The experimental group showed a signifi-
cant association with the changes in the scores for menstrual
cramps compared to the other groups after the intervention,
suggesting that aromatherapy has a beneficial effect on the
cramps experienced during the first few days of menstruation.
The experimental group showed significant improvement
of dysmenorrhea as assessed by the verbal multidimensional
scoring system. The data suggest that topically applied di-
luted essential oils of lavender, clary sage, and rose are ef-
fective in alleviating the pain of menstrual cramps. Tradi-
tionally, lavender has been used as an analgesic, sedative,
and anticonvulsant; clary sage as an anticonvulsant, regula-
tor of menstruation, and to support the actions of estrogen;
and rose to alleviate uterine problems.
28
There is a limitation associated with the blinding used in
this study. It is generally preferable to have participants ran-
domized by a third party (often the project biostatistician or
someone otherwise not associated with the study) using a
computer-generated random-number procedure. Hence, the
blinding procedure used in this study (i.e., of drawing slips
from a box) is considered inadequate.
In conclusion, this research suggests that aromatherapy
has a significant effect on menstrual cramps or dysmenor-
rhea. Because there were no side effects, aromatherapy can
be regarded as a safe, simple, cost-effective, and viable
method of nursing care suitable for all patients. However,
nurses should first undertake clinical training in aromather-
apy before incorporating it into their practice.
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Address reprint requests to:
Myung-Haeng Hur, Ph.D., R.N.
School of Nursing
Eulji University
143-5 Yongdudong, Jung-gu
Daejeon, 302-832
South Korea
E-mail: mhhur@eulji.ac.kr
Or:
daeheelee@hanafos.com
AROMATHERAPY MASSAGE EFFECT ON SYMPTOMS OF DYSMENORRHEA
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... The search and selection processes are described in the flowchart adapted from Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) 15 checklist, as can be seen in figure 1. Table 1 presents a summary of the selected articles. The final sample was composed of one article developed in South Ko-rea1 6 and three in Iran [17][18][19] , in the period from 2006 to 2020, most of them published in journals specialized on complementary therapies 16,18,19 . There was a significant difference between the groups regarding pain intensity after the intervention (p<0.042). ...
... All studies were classified with evidence level 1. As stated by the authors, the studies in the sample were: placebo-controlled randomized controlled trial 16 , randomized controlled trial 17 , single-blind randomized controlled trial 18 , and double-blind randomized controlled trial 19 . ...
... Most trials used control groups and intervention groups with lavender or other treatments [17][18][19] . One study also used a placebo group in addition to control group 16 . Pain was assessed using the visual analogue scale (VAS) in all studies. ...
... Now a days there are many attempts for alternatives traditional or herbal treatments against primary dysmenorrhea and many evidences have reported that use of natural herbs may play an important role in the case of menstrual disorders such as primary dysmenorrhea (15). Ginger is an indigenous perennial climbing plant found in South Asian countries (16). Gingerol, shogaol, paradol, zingerones, and gingerdione are components of ginger and they have antiinflammatory pharmacological acts to inhibit of prostaglandins and leukotriene biosynthesis and synthesis of inflammatory cytokines at the site of inflammation (17). ...
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Introduction. In order to assessment the effect of application ginger and lavender essential oil capsules in comparison with the mefenamic acid and paracetamol drugs on severity of primary dysmenorrhea a randomized, single-blind controlled experimental study was performed amongst 160 single teenage female students aged between 15 to 19 years who suffered from primary dysmenorrhea, and study at the Indian high school located in Bangalore in the time frame December 30, 2021 to October 30, 2022. The extent of pain was evaluated using the cox menstrual symptom scale index. Material and Method. Participants were randomly assigned to essential oil capsules or mefenamic acid as a steroidal anti-inflammatory drug and paracetamol as a prostaglandin inhibitor drug, ending with 40 participants in each group equally. The control and experimental trial groups received 250 mg of paracetamol and mefenamic acid and also herbal capsules, orally four times (each 6 hours) daily, until the pain grade reached one or less. The participants were not prohibiting taking another drug that they usually took for their pain relief, in addition to the allocated treatment in case of continued pain. At the end of the trial, these participants were excluded in data analysis. Results and Discussion. There was no significant difference was observed for the matched characteristics studied between the experimental groups. The mean pain grade amongst oral essential oil capsules were decreased, in comparison with the paracetamol and mefenamic acid drug groups. There was no statistically significant decrease in pain duration for the groups received mefenamic acid and paracetamol compared to those who used oral herbal capsules. Also, there was no significant difference in pain grade between the groups at the second month of intervention. The pain duration at the second month of trial was similar between the groups. Conclusions. In conclusion we could demonstrate that of application of essential oil capsules as a beneficial natural pain killer remedy represents effectiveness treatment for the menstrual pain with no important side effects in female teenage students.
... Though both pharmacological and non-pharmacological methods can be used to manage pain during menstruation but pharmacological methods can lead to addiction or can negative impact on cognitive function in later course of time [9]. Thus, non-pharmacological methods should be emphasized more as there is little or no effects [10]. ...
... The literature extensively documents the application of lavender essential oil in aromatherapy for various therapeutic purposes, including the management of abrasions, burns, stress, headaches, promotion of new cell growth, skin problems, alleviation of muscular pain, and enhancement of the immune system [40]. The aforementioned oil is utilised for the management of primary dysmenorrheal and has demonstrated encouraging outcomes in a randomised, double-blind clinical trial [41,42]. The efficacy of Lavender essential oil (EO) in enhancing cognitive functions such as learning and memory can be attributed to its antioxidative properties, which assist in avoiding oxidative damage, as well as its anti-apoptotic properties [43]. ...
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Alzheimer’s disease is a complex neurodegenerative disorder characterised by cognitive decline and progressive memory deterioration. Multiple hypotheses have been proposed to elucidate the pathophysiology of the phenomenon in question. At present, there exists a limited number of pharmaceutical interventions for the management of Alzheimer’s disease, with the treatment options primarily focused on alleviating symptoms rather than addressing the underlying causes of the condition. The objective of this study is to conduct a comprehensive review of the pertinent in vitro, in vivo, and clinical research pertaining to the potential therapeutic applications of essential oils in the management of Alzheimer’s disease. Data was collected by conducting a search in scientific databases, including google scholar, Scopus, ScienceDirect and PubMed. A comprehensive investigation was undertaken to explore the utilisation of diverse essential oils in various models of Alzheimer’s disease. The findings of our literary investigation indicate promising outcomes concerning the diverse essential oils that have been examined in research on Alzheimer’s disease. These oils have demonstrated notable effects in regulating the disease’s pathology through their anti-amyloid, antioxidant, anticholinesterase, and memory-enhancement properties.
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Dismenorreia é a dor pélvica que surge no primeiro dia do período menstrual, acomete muitas mulheres e pode afetar suas relações interpessoais, sua esfera social e até mesmo interferir em seu estilo de vida. As Práticas Integrativas e Complementares (PIC) podem colaborar para o alívio da dismenorreia primária. Verificar se a massagem com os óleos essenciais de Lavandula angustifólia e Pelargonium graveolens alivia a dismenorreia primária. Tratou- se de um ensaio clínico randomizado simples cego com 17 participantes que receberam esclarecimentos sobre a pesquisa e assinaram um Termo de Consentimento Livre e Esclarecido (TCLE). As participantes foram divididas de forma aleatória por meio de sorteio simples em dois grupos: o primeiro grupo recebeu massagem de 15 minutos na região abdominal com óleo de amêndoa e o segundo grupo recebeu massagem de 15 minutos na região abdominal com óleo essencial de Lavandula angustifólia (lavanda) (3%) e Pelargonium graveolens (gerânio) (2%) diluídos no óleo de amêndoa. Após o procedimento, as participantes foram avaliadas quanto a presença de dor utilizando a escala visual analógica (EVA) em dois momentos: imediatamente após o término do procedimento e 30 minutos após o procedimento. Em relação à intensidade da dor (EVA), ambos os grupos apresentaram redução significativa da dor logo após a aplicação e depois de 30 minutos do seu término em relação ao momento anterior ao procedimento. A comparação entre os grupos não mostrou diferença significativa na intensidade da dor. Conclusão: A massagem abdominal com óleo vegetal de amêndoas enriquecido ou não com óleo essencial de lavanda e gerânio é uma excelente terapia complementar para o alívio da cólica menstrual
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1 ‫ﺑﻴﺮﺟﻨﺪي‬ ‫ﺛﺎﺑﺖ‬ ‫ﺳﻤﺎﻧﻪ‬ 2 ‫ﺷﻬﺮي‬ ‫ﺧﺎﻧﻲ‬ ‫ﻣﺤﻤﺪ‬ ‫ﻫﻨﮕﺎﻣﻪ‬ 3 1 ‫ﻛﺮج‬ ‫واﺣﺪ‬ ‫اﺳﻼﻣﻲ‬ ‫آزاد‬ ‫داﻧﺸﮕﺎه‬ ‫ﻣﺎﻣﺎﻳﻲ،‬ ‫ﮔﺮوه‬ ‫ﻣﺮﺑﻲ‬ 2 ‫ﺑﻴﺮﺟ‬ ‫واﺣﺪ‬ ‫اﺳﻼﻣﻲ‬ ‫آزاد‬ ‫داﻧﺸﮕﺎه‬ ‫ﻣﺎﻣﺎﻳﻲ،‬ ‫ﮔﺮوه‬ ‫ﻣﺮﺑﻲ‬ ‫ﻨﺪ‬ 3 ‫ﺗﻬﺮان‬ ‫واﺣﺪ‬ ‫اﺳﻼﻣﻲ‬ ‫آزاد‬ ‫داﻧﺸﮕﺎه‬ ‫ﻋﻤﻮﻣﻲ،‬ ‫ﭘﺰﺷﻚ‬ ‫ﺳﺎل‬ ‫ﻫﺮﻣﺰﮔﺎن‬ ‫ﭘﺰﺷﻜﻲ‬ ‫ﻣﺠﻠﻪ‬ ‫ﻫﻔﺪﻫﻢ‬ ‫ﺷﻤﺎره‬ ‫دوم‬ ‫ﺗﻴﺮ‬ ‫و‬ ‫ﺧﺮداد‬ 92 ‫ﺻﻔﺤﺎت‬ 154-145 ‫ﭼﻜ‬ ‫ﻴ‬ ‫ﺪه‬ ‫ﻣﻘﺪﻣﻪ‬ : ‫ﻣﺪت‬ ‫ﺳﺰارﻳﻦ‬ ‫ﻋﻤﻞ‬ ‫اﻧﺠﺎم‬ ‫ﺑﻪ‬ ‫آﻧﻬﺎ‬ ‫روآوردن‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫از‬ ‫ﻣﺎدران‬ ‫ﺗﺮس‬ ‫اﺻﻠﻲ‬ ‫دﻻﻳﻞ‬ ‫از‬ ‫آن،‬ ‫درد‬ ‫ﺷﺪت‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫ﻃﻮﻻﻧﻲ‬ ‫اﺳﺖ‬. ‫رو‬ ‫اﻳﻦ‬ ‫از‬ ، ‫ﺗﻌﻴﻴﻦ‬ ‫ﻫﺪف‬ ‫ﺑﺎ‬ ‫ﺣﺎﺿﺮ‬ ‫ﭘﮋوﻫﺶ‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬ ‫ﻣﺪت‬ ‫ﻃﻮل‬ ‫ﻛﺎﻫﺶ‬ ‫ﺑﺮ‬ ‫اﺳﻄﻮﺧﻮدوس‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژي‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﺗﺄﺛﻴﺮ‬ ‫اﺳﺖ‬ ‫ﺷﺪه‬ ‫اﻧﺠﺎم‬ ‫زا‬ ‫ﻧﺨﺴﺖ‬ ‫زﻧﺎن‬ ‫زاﻳﻤﺎن‬ ‫دوم‬ ‫و‬. ‫ر‬ ‫وش‬ ‫ﻛﺎر‬ : ‫ﺳﺎل‬ ‫در‬ ‫ﻛﻪ‬ ‫اﺳﺖ‬ ‫ﺑﺎﻟﻴﻨﻲ‬ ‫ﻛﺎرآزﻣﺎﻳﻲ‬ ‫ﺣﺎﺿﺮ‬ ‫ﭘﮋوﻫﺶ‬ 1387 ‫روي‬ ‫ﺑﺮ‬ ‫ﺗﻬﺮان‬ ‫ﻣﻬﺪﻳﻪ‬ ‫ﺑﻴﻤﺎرﺳﺘﺎن‬ ‫در‬ 90 ‫ﻧﺨﺴﺖ‬ ‫زن‬ ‫زا‬ ‫اﺳﺖ‬ ‫ﺷﺪه‬ ‫اﻧﺠﺎم‬. ‫ﻧﻤﻮﻧﻪ‬ ‫ﻫﺎ‬ ‫ﺑ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫ﺳﻪ‬ ‫ﺑﻪ‬ ‫ﺗﺼﺎدﻓﻲ‬ ‫ﺻﻮرت‬ ‫ﻪ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ، ‫و‬ ‫ﺑﺎدام‬ ‫روﻏﻦ‬ ‫اﺳﺎﻧﺲ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ‫اﺳﻄﻮﺧﻮدوس‬) ‫ﻻواﻧﺪوﻻ‬ (‫ﺷﺪﻧﺪ‬ ‫ﺗﻘﺴﻴﻢ‬ ‫و‬ ‫ﺑ‬ ‫ﭘﺸﺖ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﻪ‬ ‫ﻣﺪت‬ ‫ﺑﻪ‬ ‫اﻓﻠﻮراج‬ ‫ﻃﺮﻳﻘﻪ‬ 20 ‫در‬ ‫دﻗﻴﻘﻪ‬ ‫ﮔﺮدﻳﺪ‬ ‫اﻧﺠﺎم‬ ‫دﻳﻼﺗﺎﺳﻴﻮن‬ ‫ﺳﻪ‬. ‫ﺳﭙﺲ‬ ‫ﻣﺪت‬ ‫ﻃﻮل‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫دوم‬ ‫ﻣﺮﺣﻠﻪ‬ ‫ﮔﺮ‬ ‫ﺳﻪ‬ ‫در‬ ‫رﺿﺎﻳﺘﻤﻨﺪي‬ ‫و‬ ‫درد‬ ‫ﺷﺪت‬ ، ‫ﺷﺪ‬ ‫ﺑﺮرﺳﻲ‬ ‫وه‬. ‫ﻧﺘﺎﻳﺞ‬ : ‫آﻣﺪه،‬ ‫ﺑﺪﺳﺖ‬ ‫ﻧﺘﺎﻳﺞ‬ ‫اﺳﺎس‬ ‫ﺑﺮ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫در‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫ﻣﺪت‬ ‫ﻃﻮل‬ 52 / 2 ± 321 ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫در‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫ﺑﺎدام‬ ‫روﻏﻦ‬ 81 / 2 ± 349 ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫در‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﮔﺮوه‬ 95 / 1 ± 245 ‫ﺑﻮده‬ ‫دﻗﻴﻘﻪ‬) 001 / 0 P= (. ‫دوم‬ ‫ﻣﺮﺣﻠﻪ‬ ‫ﻃﻮل‬ ‫ﻫﻤﭽﻨﻴﻦ،‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫در‬ ‫زاﻳﻤﺎن‬ 86 / 13 ± 36 / 42 ‫در‬ ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫ﺑﺎدام‬ ‫روﻏﻦ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ 22 / 12 ± 03 / 42 ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫در‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﮔﺮوه‬ 46 / 10 ± 29 ‫ﺑﻮده‬ ‫دﻗﻴﻘﻪ‬ ‫اﺳﺖ‬) 001 / 0 P= (. ‫راﺑﻄﻪ،‬ ‫اﻳﻦ‬ ‫در‬ ‫ﺷﺪت‬ ‫ﻣﻴﺎﻧﮕﻴﻦ‬ ‫ﻛﺎﻫﺶ‬ ‫ﻣﺪاﺧﻠﻪ‬ ‫از‬ ‫ﻗﺒﻞ‬ ‫ﺑﻪ‬ ‫ﻧﺴﺒﺖ‬ ‫ﻣﺪاﺧﻠﻪ‬ ‫از‬ ‫ﺑﻌﺪ‬ ‫درد‬ ‫ﻣﻬﻨﻲ‬ ‫داﺷﺖ‬ ‫داري‬) 001 / 0 P= (‫و‬ ‫ﻣﻄﺎﻟ‬ ‫دﻳﮕﺮ‬ ‫ﮔﺮوه‬ ‫دو‬ ‫ﺑﺎ‬ ‫ﻣﻘﺎﻳﺴﻪ‬ ‫در‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﻫﻤﭽﻨﻴﻦ‬ ‫از‬ ‫ﺑﻌﺪ‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫درد‬ ‫ﺷﺪت‬ ‫ﻌﻪ‬ ‫را‬ ‫ﻣﺪاﺧﻠﻪ‬ ‫اﺳﺖ‬ ‫داده‬ ‫ﻛﺎﻫﺶ‬) 001 / 0 (P= ‫و‬ ‫از‬ ‫زاﺋﻮ‬ ‫رﺿﺎﻳﺘﻤﻨﺪي‬ ‫ﺳﺒﺐ‬ ‫اﺳﺖ‬ ‫ﮔﺮدﻳﺪه‬ ‫زاﻳﻤﺎن‬) 014 / 0 P= .(‫ﻧ‬ ‫ﺘﻴﺠﻪ‬ ‫ﮔﻴﺮي‬ : ‫ﻣﻲ‬ ‫اﺳﻄﻮﺧﻮدوس‬ ‫اﺳﺎﻧﺲ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژي‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﻛﺎرﺑﺮد‬ ‫ﻛﻪ‬ ‫داد‬ ‫ﻧﺸﺎن‬ ‫ﻣﻄﺎﻟﻌﻪ‬ ‫ﻧﺘﺎﻳﺞ‬ ‫از‬ ‫ﻳﻜﻲ‬ ‫ﻋﻨﻮان‬ ‫ﺑﻪ‬ ‫ﺗﻮاﻧﺪ‬ ‫ﻋﻮارض‬ ‫ﺑﺪون‬ ‫ﻏﻴﺮداروﻳﻲ‬ ‫روﺷﻬﺎي‬ ‫و‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬ ‫ﻣﺪت‬ ‫ﺟﻨﻴﻦ‬ ‫و‬ ‫ﻣﺎدر‬ ‫روي‬ ‫ﺑﺮ‬ ‫را‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫درد‬ ‫ﺷﺪت‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫دوم‬ ‫ﻧﻤﺎﻳﺪ‬ ‫ﻛﻮﺗﺎه‬. ‫ﻛﻠﻴﺪواژه‬ ‫ﻫﺎ‬ : ‫اﺳﻄﻮﺧﻮدوس‬-‫زاﻳﻤﺎن‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬-‫زاﻳﻤﺎن‬ ‫دوم‬ ‫ﻣﺮﺣﻠﺔ‬ ‫ﻣﻘﺎﻟﻪ‬ ‫درﻳﺎﻓﺖ‬ : 29 / 5 / 90 ‫ﻧﻬﺎﻳﻲ‬ ‫اﺻﻼح‬ : 18 / 6 / 91 ‫ﻣﻘﺎﻟﻪ‬ ‫ﭘﺬﻳﺮش‬ : 11 / 7 / 91 ‫ﻣﻘﺪﻣﻪ‬ : ‫زاﻳﻤﺎن‬ ‫ﺷﻴﻮع‬ ‫ﻣﺘﻮﺳﻂ‬ ‫ﻃﻮر‬ ‫ﺑﻪ‬ ‫ﻃﻮﻻﻧﻲ‬ 8-3 ‫و‬ ‫ﺑﻮده‬ ‫درﺻﺪ‬ ‫زاﻳﺎن‬ ‫ﻧﺨﺴﺖ‬ ‫ﻣﻴﺎن‬ ‫در‬ ‫درﺻﺪ‬ ‫اﻳﻦ‬ 3 ‫ﺷﺎﻳﻊ‬ ‫ﺑﺮاﺑﺮ‬ ‫ﭼﻨﺪزاﻳﺎن‬ ‫از‬ ‫ﺗﺮ‬ ‫اﺳﺖ‬) 1 .(‫اﻓﺰاﻳﺶ‬ ‫ﺑﺎﻋﺚ‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫در‬ ‫اﺿﻄﺮاب‬ ‫و‬ ‫ﺷﺪﻳﺪ‬ ‫درد‬ ‫ﻛﻮرﺗﻴﺰول‬ ‫ﻫﻮرﻣﻮن‬ ‫ﭘﻼﺳﻤﺎﻳﻲ‬ ‫ﻣﻴﺰان‬ ‫اﻓﺰاﻳﺶ‬ ‫و‬ ‫ﻫﺎ‬ ‫ﻛﺎﺗﻜﻮﻻﻣﻴﻦ‬ ‫ﻣﻲ‬ ‫و‬ ‫ﻳﺎﻓﺘﻪ‬ ‫ﻛﺎﻫﺶ‬ ‫رﺣﻢ‬ ‫اﻧﻘﺒﺎﺿﻲ‬ ‫ﻗﺪرت‬ ‫آن‬ ‫ﻧﺘﻴﺠﺔ‬ ‫در‬ ‫ﻛﻪ‬ ‫ﮔﺮدد‬ ‫ﻧﺎﻫ‬ ‫ﺑﻪ‬ ‫ﻣﻨﺠﺮ‬ ‫ﺷﺪن‬ ‫ﻃﻮﻻﻧﻲ‬ ‫ﺑﻪ‬ ‫ﻣﻨﺠﺮ‬ ‫ﻧﻬﺎﻳﺖ‬ ‫در‬ ‫و‬ ‫اﻧﻘﺒﺎﺿﺎت‬ ‫ﻤﺎﻫﻨﮕﻲ‬ ‫ﻣﻲ‬ ‫زاﻳﻤﺎن‬ ‫ﭘﻴﺸﺮﻓﺖ‬ ‫ﺳﺮﻋﺖ‬ ‫ﻛﺎﻫﺶ‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫ﮔﺮدد‬) 2 .(‫ﻣﺪت‬ ‫ﻃﻮل‬ ‫ﻣﺎدر‬ ‫ﺑﺮ‬ ‫وارده‬ ‫آﺳﻴﺒﻬﺎي‬ ‫و‬ ‫ﺣﺎﻣﻠﮕﻲ‬ ‫ﻧﺘﺎﻳﺞ‬ ‫ﺑﺮ‬ ‫ﻣﺆﺛﺮ‬ ‫ﻋﻮاﻣﻞ‬ ‫از‬ ‫زاﻳﻤﺎن‬ ‫اﺳﺖ‬ ‫ﺟﻨﻴﻦ‬ ‫و‬. ‫زاﻳﻤﺎن‬ ‫ﺣﺪ‬ ‫از‬ ‫ﺑﻴﺶ‬ ‫ﺷﺪن‬ ‫ﻃﻮﻻﻧﻲ‬ ‫ﺑﺎ‬ ‫ﻛﻪ‬ ‫ﻃﻮري‬ ‫ﺑﻪ‬ ‫ﺟﺴﻤﻲ‬ ‫ﺻﺪﻣﺎت‬ ‫ﻋﻔﻮﻧﺖ،‬ ‫اﺣﺘﻤﺎل‬-‫و‬ ‫ﻋﺼﺒﻲ‬ ‫در‬ ‫ﻣﺮگ‬ ‫و‬ ‫ﺟﻨﻴﻦ‬ ‫ﻋﻔﻮﻧﺖ‬ ‫و‬ ‫ﺧﻮﻧﺮﻳﺰي‬ ‫ﻣﻌﺮض‬ ‫در‬ ‫ﻧﻴﺰ‬ ‫ﻣﺎدر‬ ‫و‬ ‫ﻳﺎﻓﺘﻪ‬ ‫اﻓﺰاﻳﺶ‬ ‫ﻧﻮزاد‬ ‫ﺑﻲ‬ ‫اﺿﻄﺮاب،‬ ‫از‬ ‫ﺣﺎﺻﻞ‬ ‫آﺷﻔﺘﮕﻲ‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫از‬ ‫ﺑﻌﺪ‬ ‫و‬ ‫ﺧﻮاﺑﻲ‬ ‫ﻣﻲ‬ ‫ﻗﺮار‬ ‫ﺧﺴﺘﮕﻲ‬ ‫ﮔﻴﺮد‬) 3 .(‫ﻋﺒﺎﺳﻲ‬ ‫ﻣﻄﺎﻟﻌﻪ‬ ‫ﻃﺒﻖ‬ ‫ﺑﺮ‬ ، ‫ﻃﻮﻻﻧﻲ‬ ‫زاﻳﻤﺎن
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1 ‫ﺑﻴﺮﺟﻨﺪي‬ ‫ﺛﺎﺑﺖ‬ ‫ﺳﻤﺎﻧﻪ‬ 2 ‫ﺷﻬﺮي‬ ‫ﺧﺎﻧﻲ‬ ‫ﻣﺤﻤﺪ‬ ‫ﻫﻨﮕﺎﻣﻪ‬ 3 1 ‫ﻛﺮج‬ ‫واﺣﺪ‬ ‫اﺳﻼﻣﻲ‬ ‫آزاد‬ ‫داﻧﺸﮕﺎه‬ ‫ﻣﺎﻣﺎﻳﻲ،‬ ‫ﮔﺮوه‬ ‫ﻣﺮﺑﻲ‬ 2 ‫ﺑﻴﺮﺟ‬ ‫واﺣﺪ‬ ‫اﺳﻼﻣﻲ‬ ‫آزاد‬ ‫داﻧﺸﮕﺎه‬ ‫ﻣﺎﻣﺎﻳﻲ،‬ ‫ﮔﺮوه‬ ‫ﻣﺮﺑﻲ‬ ‫ﻨﺪ‬ 3 ‫ﺗﻬﺮان‬ ‫واﺣﺪ‬ ‫اﺳﻼﻣﻲ‬ ‫آزاد‬ ‫داﻧﺸﮕﺎه‬ ‫ﻋﻤﻮﻣﻲ،‬ ‫ﭘﺰﺷﻚ‬ ‫ﺳﺎل‬ ‫ﻫﺮﻣﺰﮔﺎن‬ ‫ﭘﺰﺷﻜﻲ‬ ‫ﻣﺠﻠﻪ‬ ‫ﻫﻔﺪﻫﻢ‬ ‫ﺷﻤﺎره‬ ‫دوم‬ ‫ﺗﻴﺮ‬ ‫و‬ ‫ﺧﺮداد‬ 92 ‫ﺻﻔﺤﺎت‬ 154-145 ‫ﭼﻜ‬ ‫ﻴ‬ ‫ﺪه‬ ‫ﻣﻘﺪﻣﻪ‬ : ‫ﻣﺪت‬ ‫ﺳﺰارﻳﻦ‬ ‫ﻋﻤﻞ‬ ‫اﻧﺠﺎم‬ ‫ﺑﻪ‬ ‫آﻧﻬﺎ‬ ‫روآوردن‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫از‬ ‫ﻣﺎدران‬ ‫ﺗﺮس‬ ‫اﺻﻠﻲ‬ ‫دﻻﻳﻞ‬ ‫از‬ ‫آن،‬ ‫درد‬ ‫ﺷﺪت‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫ﻃﻮﻻﻧﻲ‬ ‫اﺳﺖ‬. ‫رو‬ ‫اﻳﻦ‬ ‫از‬ ، ‫ﺗﻌﻴﻴﻦ‬ ‫ﻫﺪف‬ ‫ﺑﺎ‬ ‫ﺣﺎﺿﺮ‬ ‫ﭘﮋوﻫﺶ‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬ ‫ﻣﺪت‬ ‫ﻃﻮل‬ ‫ﻛﺎﻫﺶ‬ ‫ﺑﺮ‬ ‫اﺳﻄﻮﺧﻮدوس‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژي‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﺗﺄﺛﻴﺮ‬ ‫اﺳﺖ‬ ‫ﺷﺪه‬ ‫اﻧﺠﺎم‬ ‫زا‬ ‫ﻧﺨﺴﺖ‬ ‫زﻧﺎن‬ ‫زاﻳﻤﺎن‬ ‫دوم‬ ‫و‬. ‫ر‬ ‫وش‬ ‫ﻛﺎر‬ : ‫ﺳﺎل‬ ‫در‬ ‫ﻛﻪ‬ ‫اﺳﺖ‬ ‫ﺑﺎﻟﻴﻨﻲ‬ ‫ﻛﺎرآزﻣﺎﻳﻲ‬ ‫ﺣﺎﺿﺮ‬ ‫ﭘﮋوﻫﺶ‬ 1387 ‫روي‬ ‫ﺑﺮ‬ ‫ﺗﻬﺮان‬ ‫ﻣﻬﺪﻳﻪ‬ ‫ﺑﻴﻤﺎرﺳﺘﺎن‬ ‫در‬ 90 ‫ﻧﺨﺴﺖ‬ ‫زن‬ ‫زا‬ ‫اﺳﺖ‬ ‫ﺷﺪه‬ ‫اﻧﺠﺎم‬. ‫ﻧﻤﻮﻧﻪ‬ ‫ﻫﺎ‬ ‫ﺑ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫ﺳﻪ‬ ‫ﺑﻪ‬ ‫ﺗﺼﺎدﻓﻲ‬ ‫ﺻﻮرت‬ ‫ﻪ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ، ‫و‬ ‫ﺑﺎدام‬ ‫روﻏﻦ‬ ‫اﺳﺎﻧﺲ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ‫اﺳﻄﻮﺧﻮدوس‬) ‫ﻻواﻧﺪوﻻ‬ (‫ﺷﺪﻧﺪ‬ ‫ﺗﻘﺴﻴﻢ‬ ‫و‬ ‫ﺑ‬ ‫ﭘﺸﺖ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﻪ‬ ‫ﻣﺪت‬ ‫ﺑﻪ‬ ‫اﻓﻠﻮراج‬ ‫ﻃﺮﻳﻘﻪ‬ 20 ‫در‬ ‫دﻗﻴﻘﻪ‬ ‫ﮔﺮدﻳﺪ‬ ‫اﻧﺠﺎم‬ ‫دﻳﻼﺗﺎﺳﻴﻮن‬ ‫ﺳﻪ‬. ‫ﺳﭙﺲ‬ ‫ﻣﺪت‬ ‫ﻃﻮل‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫دوم‬ ‫ﻣﺮﺣﻠﻪ‬ ‫ﮔﺮ‬ ‫ﺳﻪ‬ ‫در‬ ‫رﺿﺎﻳﺘﻤﻨﺪي‬ ‫و‬ ‫درد‬ ‫ﺷﺪت‬ ، ‫ﺷﺪ‬ ‫ﺑﺮرﺳﻲ‬ ‫وه‬. ‫ﻧﺘﺎﻳﺞ‬ : ‫آﻣﺪه،‬ ‫ﺑﺪﺳﺖ‬ ‫ﻧﺘﺎﻳﺞ‬ ‫اﺳﺎس‬ ‫ﺑﺮ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫در‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫ﻣﺪت‬ ‫ﻃﻮل‬ 52 / 2 ± 321 ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫در‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫ﺑﺎدام‬ ‫روﻏﻦ‬ 81 / 2 ± 349 ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫در‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﮔﺮوه‬ 95 / 1 ± 245 ‫ﺑﻮده‬ ‫دﻗﻴﻘﻪ‬) 001 / 0 P= (. ‫دوم‬ ‫ﻣﺮﺣﻠﻪ‬ ‫ﻃﻮل‬ ‫ﻫﻤﭽﻨﻴﻦ،‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ ‫در‬ ‫زاﻳﻤﺎن‬ 86 / 13 ± 36 / 42 ‫در‬ ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫ﺑﺎدام‬ ‫روﻏﻦ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژ‬ ‫ﮔﺮوه‬ 22 / 12 ± 03 / 42 ‫و‬ ‫دﻗﻴﻘﻪ‬ ‫در‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﮔﺮوه‬ 46 / 10 ± 29 ‫ﺑﻮده‬ ‫دﻗﻴﻘﻪ‬ ‫اﺳﺖ‬) 001 / 0 P= (. ‫راﺑﻄﻪ،‬ ‫اﻳﻦ‬ ‫در‬ ‫ﺷﺪت‬ ‫ﻣﻴﺎﻧﮕﻴﻦ‬ ‫ﻛﺎﻫﺶ‬ ‫ﻣﺪاﺧﻠﻪ‬ ‫از‬ ‫ﻗﺒﻞ‬ ‫ﺑﻪ‬ ‫ﻧﺴﺒﺖ‬ ‫ﻣﺪاﺧﻠﻪ‬ ‫از‬ ‫ﺑﻌﺪ‬ ‫درد‬ ‫ﻣﻬﻨﻲ‬ ‫داﺷﺖ‬ ‫داري‬) 001 / 0 P= (‫و‬ ‫ﻣﻄﺎﻟ‬ ‫دﻳﮕﺮ‬ ‫ﮔﺮوه‬ ‫دو‬ ‫ﺑﺎ‬ ‫ﻣﻘﺎﻳﺴﻪ‬ ‫در‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﻫﻤﭽﻨﻴﻦ‬ ‫از‬ ‫ﺑﻌﺪ‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫درد‬ ‫ﺷﺪت‬ ‫ﻌﻪ‬ ‫را‬ ‫ﻣﺪاﺧﻠﻪ‬ ‫اﺳﺖ‬ ‫داده‬ ‫ﻛﺎﻫﺶ‬) 001 / 0 (P= ‫و‬ ‫از‬ ‫زاﺋﻮ‬ ‫رﺿﺎﻳﺘﻤﻨﺪي‬ ‫ﺳﺒﺐ‬ ‫اﺳﺖ‬ ‫ﮔﺮدﻳﺪه‬ ‫زاﻳﻤﺎن‬) 014 / 0 P= .(‫ﻧ‬ ‫ﺘﻴﺠﻪ‬ ‫ﮔﻴﺮي‬ : ‫ﻣﻲ‬ ‫اﺳﻄﻮﺧﻮدوس‬ ‫اﺳﺎﻧﺲ‬ ‫ﺑﺎ‬ ‫ﻣﺎﺳﺎژي‬ ‫آروﻣﺎﺗﺮاﭘﻲ‬ ‫ﻛﺎرﺑﺮد‬ ‫ﻛﻪ‬ ‫داد‬ ‫ﻧﺸﺎن‬ ‫ﻣﻄﺎﻟﻌﻪ‬ ‫ﻧﺘﺎﻳﺞ‬ ‫از‬ ‫ﻳﻜﻲ‬ ‫ﻋﻨﻮان‬ ‫ﺑﻪ‬ ‫ﺗﻮاﻧﺪ‬ ‫ﻋﻮارض‬ ‫ﺑﺪون‬ ‫ﻏﻴﺮداروﻳﻲ‬ ‫روﺷﻬﺎي‬ ‫و‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬ ‫ﻣﺪت‬ ‫ﺟﻨﻴﻦ‬ ‫و‬ ‫ﻣﺎدر‬ ‫روي‬ ‫ﺑﺮ‬ ‫را‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫درد‬ ‫ﺷﺪت‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫دوم‬ ‫ﻧﻤﺎﻳﺪ‬ ‫ﻛﻮﺗﺎه‬. ‫ﻛﻠﻴﺪواژه‬ ‫ﻫﺎ‬ : ‫اﺳﻄﻮﺧﻮدوس‬-‫زاﻳﻤﺎن‬ ‫اول‬ ‫ﻣﺮﺣﻠﺔ‬-‫زاﻳﻤﺎن‬ ‫دوم‬ ‫ﻣﺮﺣﻠﺔ‬ ‫ﻣﻘﺎﻟﻪ‬ ‫درﻳﺎﻓﺖ‬ : 29 / 5 / 90 ‫ﻧﻬﺎﻳﻲ‬ ‫اﺻﻼح‬ : 18 / 6 / 91 ‫ﻣﻘﺎﻟﻪ‬ ‫ﭘﺬﻳﺮش‬ : 11 / 7 / 91 ‫ﻣﻘﺪﻣﻪ‬ : ‫زاﻳﻤﺎن‬ ‫ﺷﻴﻮع‬ ‫ﻣﺘﻮﺳﻂ‬ ‫ﻃﻮر‬ ‫ﺑﻪ‬ ‫ﻃﻮﻻﻧﻲ‬ 8-3 ‫و‬ ‫ﺑﻮده‬ ‫درﺻﺪ‬ ‫زاﻳﺎن‬ ‫ﻧﺨﺴﺖ‬ ‫ﻣﻴﺎن‬ ‫در‬ ‫درﺻﺪ‬ ‫اﻳﻦ‬ 3 ‫ﺷﺎﻳﻊ‬ ‫ﺑﺮاﺑﺮ‬ ‫ﭼﻨﺪزاﻳﺎن‬ ‫از‬ ‫ﺗﺮ‬ ‫اﺳﺖ‬) 1 .(‫اﻓﺰاﻳﺶ‬ ‫ﺑﺎﻋﺚ‬ ‫زاﻳﻤﺎن‬ ‫ﻓﻌﺎل‬ ‫ﻓﺎز‬ ‫در‬ ‫اﺿﻄﺮاب‬ ‫و‬ ‫ﺷﺪﻳﺪ‬ ‫درد‬ ‫ﻛﻮرﺗﻴﺰول‬ ‫ﻫﻮرﻣﻮن‬ ‫ﭘﻼﺳﻤﺎﻳﻲ‬ ‫ﻣﻴﺰان‬ ‫اﻓﺰاﻳﺶ‬ ‫و‬ ‫ﻫﺎ‬ ‫ﻛﺎﺗﻜﻮﻻﻣﻴﻦ‬ ‫ﻣﻲ‬ ‫و‬ ‫ﻳﺎﻓﺘﻪ‬ ‫ﻛﺎﻫﺶ‬ ‫رﺣﻢ‬ ‫اﻧﻘﺒﺎﺿﻲ‬ ‫ﻗﺪرت‬ ‫آن‬ ‫ﻧﺘﻴﺠﺔ‬ ‫در‬ ‫ﻛﻪ‬ ‫ﮔﺮدد‬ ‫ﻧﺎﻫ‬ ‫ﺑﻪ‬ ‫ﻣﻨﺠﺮ‬ ‫ﺷﺪن‬ ‫ﻃﻮﻻﻧﻲ‬ ‫ﺑﻪ‬ ‫ﻣﻨﺠﺮ‬ ‫ﻧﻬﺎﻳﺖ‬ ‫در‬ ‫و‬ ‫اﻧﻘﺒﺎﺿﺎت‬ ‫ﻤﺎﻫﻨﮕﻲ‬ ‫ﻣﻲ‬ ‫زاﻳﻤﺎن‬ ‫ﭘﻴﺸﺮﻓﺖ‬ ‫ﺳﺮﻋﺖ‬ ‫ﻛﺎﻫﺶ‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫ﮔﺮدد‬) 2 .(‫ﻣﺪت‬ ‫ﻃﻮل‬ ‫ﻣﺎدر‬ ‫ﺑﺮ‬ ‫وارده‬ ‫آﺳﻴﺒﻬﺎي‬ ‫و‬ ‫ﺣﺎﻣﻠﮕﻲ‬ ‫ﻧﺘﺎﻳﺞ‬ ‫ﺑﺮ‬ ‫ﻣﺆﺛﺮ‬ ‫ﻋﻮاﻣﻞ‬ ‫از‬ ‫زاﻳﻤﺎن‬ ‫اﺳﺖ‬ ‫ﺟﻨﻴﻦ‬ ‫و‬. ‫زاﻳﻤﺎن‬ ‫ﺣﺪ‬ ‫از‬ ‫ﺑﻴﺶ‬ ‫ﺷﺪن‬ ‫ﻃﻮﻻﻧﻲ‬ ‫ﺑﺎ‬ ‫ﻛﻪ‬ ‫ﻃﻮري‬ ‫ﺑﻪ‬ ‫ﺟﺴﻤﻲ‬ ‫ﺻﺪﻣﺎت‬ ‫ﻋﻔﻮﻧﺖ،‬ ‫اﺣﺘﻤﺎل‬-‫و‬ ‫ﻋﺼﺒﻲ‬ ‫در‬ ‫ﻣﺮگ‬ ‫و‬ ‫ﺟﻨﻴﻦ‬ ‫ﻋﻔﻮﻧﺖ‬ ‫و‬ ‫ﺧﻮﻧﺮﻳﺰي‬ ‫ﻣﻌﺮض‬ ‫در‬ ‫ﻧﻴﺰ‬ ‫ﻣﺎدر‬ ‫و‬ ‫ﻳﺎﻓﺘﻪ‬ ‫اﻓﺰاﻳﺶ‬ ‫ﻧﻮزاد‬ ‫ﺑﻲ‬ ‫اﺿﻄﺮاب،‬ ‫از‬ ‫ﺣﺎﺻﻞ‬ ‫آﺷﻔﺘﮕﻲ‬ ‫و‬ ‫زاﻳﻤﺎن‬ ‫از‬ ‫ﺑﻌﺪ‬ ‫و‬ ‫ﺧﻮاﺑﻲ‬ ‫ﻣﻲ‬ ‫ﻗﺮار‬ ‫ﺧﺴﺘﮕﻲ‬ ‫ﮔﻴﺮد‬) 3 .(‫ﻋﺒﺎﺳﻲ‬ ‫ﻣﻄﺎﻟﻌﻪ‬ ‫ﻃﺒﻖ‬ ‫ﺑﺮ‬ ، ‫ﻃﻮﻻﻧﻲ‬ ‫زاﻳﻤﺎن
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Background: Plant-based remedies have been used since antiquity to treat menstrual-related diseases (MD). From the late nineteenth to the early to mid-twentieth century, Italian folk remedies to treat “women’s diseases” were documented in a vast corpus of literature sources. Aim: The purpose of this paper is to bring to light the plant-based treatments utilized by Italian folk medicine to heal clinical manifestations of premenstrual syndrome (PMS), dysmenorrhea, amenorrhea and menstrual disorders in an attempt to discuss these remedies from a modern pharmacological point of view. Moreover, we compare the medical applications described by Hippocrates with those utilized by Italian folk medicine to check if they result from a sort of continuity of use by over two thousand years. Results: Out of the 54 plants employed in Italian folk medicine, 25 (46.3%) were already documented in the pharmacopoeia of the Corpus Hippocraticum for treating MD. Subsequently, a detailed search of scientific data banks such as Medline and Scopus was undertaken to uncover recent results concerning bioactivities of the plant extracts to treat MD. About 26% of the plants used by Italian folk medicine, nowadays, have undergone human trials to assess their actual efficacy. At the same time, about 41% of these herbal remedies come back to in different countries. Conclusions: Active principles extracted from plants used by Italian folk healers could be a promising source of knowledge and represent strength candidates for future drug discovery for the management of MD.
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colon; To determine the effectiveness of a single treatment with acupuncture-like transcutaneous electrical nerve stimulation (TENS) for relief of primary dysmenorrheic pain, 20 women received either one placebo sugar pill or 30 min of acupuncture-like TENS at four acupuncture points bilaterally. Pain levels were measured using the visual analogue scale and McGill pain rating index for up to 150 min following treatment. Results showed that the experimental groups attained a statistically significant (p < 0.05) amount of pain relief and the control group did not. The results of this study indicate that acupuncture-like TENS could be an alternative for relief of menstrual pain. (C) Lippincott-Raven Publishers.
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The purpose of this study was to replicate a previous study to determine the effectiveness of acupuncture-like transcutaneous electrical nerve stimulation in treating primary dysmenorrhea. Twenty-one women with dysmenorrhea received a placebo pill or 30 minutes of acupuncture-like TENS. All subjects completed two pain questionnaires before treatment; immediately posttreatment; 30, 60, 120, and 180 minutes posttreatment; and the next morning upon awakening. Each woman also participated in a separate study measuring electrical resistance at four auricular acupuncture points before and immediately after treatment. The data were analyzed with a two-factor repeated-measures analysis of variance, which revealed statistical significance over time but not for group or interaction between group and time. Results revealed an average pain relief of at least 50% immediately posttreatment, indicating that acupuncture-like TENS may be useful for dysmenorrheic pain. This study also suggests that auriculotherapy via acupressure may relieve the pain of primary dysmenorrhea.
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The effects of flurbiprofen (100 mg) and naproxen sodium (500 mg) on intrauterine pressure and menstrual pain were assessed in 8 women with primary dysmenorrhea using a double-blind parallel study technique. Intrauterine pressure was recorded with a microtransducer catheter for 4 h and resting pressure, active pressure, frequency of pressure cycles, and the area under the curve were analysed in 30 min periods. Prior to medication all the patients displayed signs of uterine hyperactivity as judged by a high resting pressure 55.3 +/- 3.8 mm Hg, high active pressure 175.0 +/- 6.1 mm Hg and a high frequency of pressure cycles 12.3 +/- 0.7 contractions per 0.5 h. Oral administration of flurbiprofen and naproxen sodium significantly suppressed uterine activity and was associated with a significant reduction in pain intensity. However no significant differences were recorded between the two drugs regarding their effects on intrauterine pressure and pain intensity.
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