Community annotation: Procedures, protocols, and supporting tools

Department of Animal Science, Texas A&M University, College Station, Texas 77843, USA.
Genome Research (Impact Factor: 14.63). 12/2006; 16(11):1329-33. DOI: 10.1101/gr.5580606
Source: PubMed


Investigators at the Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) and BeeBase organized a community-wide effort to manually annotate the honey bee (Apis mellifera) genome. Although various strategies for manual annotation have been used in the past, the value of dispersed community annotation has not yet been demonstrated. Here we make a case for the merit of dispersed community annotation. We present annotation procedures, standard protocols, and tools used for sequence analysis, data submission, and data management. We also report lessons learned from this dispersed community annotation effort for a metazoan genome.

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Available from: George Weinstock, Jan 17, 2016
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    • "Their phylogeny and branch information with D. mel are shown in supplementary figure S17, Supplementary Material online. The gene annotations were downloaded from BeeBase (Elsik et al. 2006), BeetleBase (Wang et al. 2007), SilkDB (Wang et al. 2005), and Ensembl (Hubbard et al. 2007), respectively. The species tree of a previous study (Zdobnov and Bork 2007) was used. "
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