Cerebrovascular disease basis of depression: Post-stroke depression and vascular depression

ArticleinInternational Review of Psychiatry 18(5):433-41 · November 2006with5 Reads
Impact Factor: 1.80 · DOI: 10.1080/09540260600935447 · Source: PubMed


    The close association between cerebrovascular disease and depression has been known for more than a century, yet much of the progress in understanding the cerebrovascular basis of depression in late life has been spurred by development of two concepts: 'post-stroke depression' and 'vascular depression'. The purpose of this review is to examine the epidemiology, diagnostic features, course, pathophysiology and prognosis of post-stroke depression and vascular depression, to highlight their common features, and to contrast the distinct aspects of these two subtypes of geriatric depression.