Fear of progression in breast cancer patients—validation of the short form of the Progredienzangstfragebogen PA-F-KF (Fear of Progression Questionnaire; FoP-Q-SF)

Institut und Poliklinik für Medizinische Psychologie, Zentrum für Psychosoziale Medizin, Universitätsklinikum Hamburg-Eppendorf.
Zeitschrift fur Psychosomatische Medizin und Psychotherapie (Impact Factor: 0.86). 01/2006; 52(3):274-88. DOI: 10.13109/zptm.2006.52.3.274
Source: PubMed


Fear of progression is one of the most prevalent symptoms in cancer patients. The aim of this study was to validate the 12-item short version of the Fear of Progression Questionnaire (FoP-Q-SF).
A total of 1083 breast cancer patients were recruited by the Hamburg Cancer Register to fill out various questionnaires (response rate 67 %).
Estimates of reliability were high (Cronbach's alpha = .87). The original one-factor structure was replicated. We used the HADS, the PCL-C, and the SF-8, among others, to validate the FoP-Q-SF. Significant positive correlations were found for fear of progression, anxiety and intrusion (r > .60) as well as for avoidance, hyperarousal and depression (r > or = .49). Moderate to high (negative) correlations were observed with health-related quality of life, in particular with the mental health dimensions (r > or = .48). Patients with cancer recurrence reported significant higher levels of fear of progression (p < .001).
The short form of the Fear of Progression Questionnaire appears to be a reliable and valid instrument which can be recommended for further use in research and clinical care.

    • "All eligible patients in both clinics were invited to participate in the study by their attending rheumatologist. In addition to the inclusion and exclusion criteria of the cohort study, inclusion criteria for the present intervention were: (1) a score C16 on the Center for Epidemiologic Studies-Depression (CES-D; Radloff, 1977) at two consecutive measures that were 6 months apart; (2) a score C34 on the Fear of Progression- Questionnaire Short Form (FoP-Q-SF; Herschbach et al., 2005; Mehnert et al., 2006); and (3) a one-way travel time of B60 min to our hospital. A score C16 on the CES-D is indicative of significant depressive symptoms and is a widely used cut-off score to aid in identifying patients with a possible clinical depression (Radloff, 1977). "
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