A rapid screening battery to identify frontal dysfunction in patients with ALS

Article (PDF Available)inNeurology 67(11):2070-2 · January 2007with18 Reads
DOI: 10.1212/01.wnl.0000247667.89251.43 · Source: PubMed
We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.