Gonorrhoea and male bladder cancer in a prospective study

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
British Journal of Cancer (Impact Factor: 4.84). 02/2007; 96(1):169-71. DOI: 10.1038/sj.bjc.6603510
Source: PubMed


In a prospective cohort study, a close to two-fold elevated risk of bladder cancer was found among men reporting a history of gonorrhoea (relative risk=1.92, 95% CI=1.10-3.33). Our finding warrants further examination of the role of gonorrhoea in bladder carcinogenesis.

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    • "Although the majority of bladder tumors formed due to Schistosoma infection are squamous cell carcinomas (SCC), adenocarcinomas and transitional cell carcinomas (TCC) or undifferentiated carcinomas can develop (Johansson & Cohen, 1997 ) Furthermore, it appears that there is a proportional increase of TCC due to schistosomal infections over time (Koraitim et al.,1995). Some researchers believe that TCC need more time to progress than SCC and are closely related with a less devastating inflammatory infiltrate (Michaud et al., 2007). "

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