Article

Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years

Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London, Box P023, De Crespigny Park, London SE5 8AF, UK.
Schizophrenia Research (Impact Factor: 3.92). 03/2007; 90(1-3):130-46. DOI: 10.1016/j.schres.2006.11.006
Source: PubMed

ABSTRACT

Prospective longitudinal investigations are needed to identify causal processes leading to schizophrenia. However, there is presently no cost-effective way to identify children who are at risk of developing schizophrenia spectrum disorders: Although having a family history of schizophrenia is associated with elevated risk for developing spectrum disorders, the majority of individuals with schizophrenia do not have an afflicted relative. The present study aimed to test the feasibility of screening a community sample of children, aged 9 to 12 years, to identify children who experienced a triad of putative antecedents of schizophrenia that had been identified from previous research, including: (1) speech and/or motor development lags or problems; (2) social, emotional, or behavioural problems; and (3) psychotic-like-experiences (PLEs). 548 children and 264 caregivers completed questionnaires. 9.2% of boys and 4.1% of girls displayed the triad of antecedents. 58.9% of the children reported "certain experience" of one or more PLEs. The results suggest that questionnaire screening of community samples of children for the putative antecedents of schizophrenia spectrum disorders is feasible. Accuracy of identification will only be established by follow-up studies.

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    • "Although the scree plot suggested the single-factor solution, the unidimensionality of the PDI could not been confirmed by the confirmatory factor analysis (the asymptotically distribution free method) because of the small size of the study sample. What is more, specifying the prevalence of delusion-like experiences on the basis of the results of self-reports can distort these results and show higher values than real prevalence of delusion-like experiences [44, 45]. However, the results of previous studies show that scale scores on the basis of self-reports also allow to accurately calculate the risk of psychotic dis- orders [9, 15] and to predict the development of psychosis [27, 46, 47]. "

    Full-text · Article · Dec 2015 · Psychiatria polska
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    • "Briefly, children aged 9–12 years and their caregivers independently completed questionnaires, at school and at home, respectively, assessing a triad of antecedents of schizophrenia, including: (i) a speech and/or motor delay or abnormality ; (ii) a social, emotional and/or behavioural problem; and (iii) a psychotic-like experience. Delays or abnormalities in speech and/or motor development were assessed via nine items included in the caregiver questionnaire (Laurens et al. 2007). Social, emotional and behavioural problems were defined as a score in the clinical range on at least one of the four psychopathology scales of the Strengths and Difficulties Questionnaire (SDQ; Goodman, 2001): emotional symptoms (childreported ); conduct problems; hyperactivity–inattention; and peer relationship problems (caregiver-reported). Psychotic-like experiences were assessed via nine items in the child questionnaire (Laurens et al. 2012); each item was rated on a three-point scale (0 = not true, 1 = somewhat true, 2 = certainly true) with a score of 2 on any item indicating a positive rating. "
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    • "in children and adolescents reported an extremely wide prevalence range across studies, with rates of up to 90% (Kelleher et al. 2012a). The authors restricted their analyses to the item of hearing voices and calculated a median prevalence of 17% among children (aged 9–12 years) and 7.5% among adolescents (aged 13–18 years) (Kelleher et al. 2012a).Laurens et al. (2007)found rates of PE in various ethnic groups between 40% and 70% and followed another strategy by defining a triad of putative schizophrenia antecedents , including developmental delays and high scores of other psychiatric symptoms. Between 0 Psychotic experiences among ethnic minority youth 643 (South Asian) and 15% (African-Caribbean) of"
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