Atypical metanephric adenoma - A case report and review of literature

ArticleinInternational Urology and Nephrology 39(1):123-7 · February 2007with4 Reads
Impact Factor: 1.52 · DOI: 10.1007/s11255-005-4970-y · Source: PubMed
  • 31.45 · Sanjay Gandhi Post Graduate Institute of Medical Sciences
  • 43.53 · Borlaug Institute for South Asia, NASC Complex, Pusa, New Delhi 110012

Metanephric adenoma (MA) is a rare renal neoplasm that generally occurs in adults and is considered to have a good prognosis. However, one case of MA with atypical histological features and distant metastasis and another case of metastasizing MA with typical cytologic features have been reported. The authors here report a case of MA with atypical histological features arising in the left kidney of an 18-year-old girl presenting with painless hematuria. Relevant literature is reviewed and discussed.

  • [Show abstract] [Hide abstract] ABSTRACT: A 60-year-old woman presented with epigastlagia and admitted to our hospital. Urtrasonography, computed tomography and angiography revealed right renal cell carcinoma. We performed right laparoscopic radical nephrectomy. Histopathological examination of the mass was consistent with metanephric adenoma. Relevant literature is reviewed and discussed. {Rinsho Hinyokika 63 : 633-635, 2009).
    No preview · Article · Jan 2009 · Japanese Journal of Clinical Urology
  • [Show abstract] [Hide abstract] ABSTRACT: Metanephric adenoma (MA) is a renal tumor that is rarely diagnosed in children. Although it is considered benign and to have a good prognosis, the diagnosis of MA is challenging because of histopathologic and radiologic similarities to Wilms tumor. In this case report, we present a 6-year-old girl, with a renal mass and right hemihypertrophy, who was previously diagnosed as Wilms tumor on a fine-needle biopsy and diagnosed as MA after nephroureterectomy. The differentiation between Wilms tumor and metanephric adenoma is also discussed.
    No preview · Article · Jul 2009 · Journal of Pediatric Hematology/Oncology
  • [Show abstract] [Hide abstract] ABSTRACT: SUMMARY: Renal metanephric adenoma (MA) is an extremely rare benign tumor, especially in children under the age of 12 years old. In this article, we report a case of MA that was incidentally discovered in a 2-year-old girl by ultrasound. Magnetic resonance scan revealed a mass of right kidney that was hypointense and hyperintense on T1- and T2-weighted images, respectively. Laparoscopic nephron-sparing surgery was carried out to remove the lesion. Histopathologic examination of the specimen revealed MA with clear surgical margins. Immunohistochemically, the tumor cells showed focal reactivity for CD56, pan-cytokeratin (AE1/AE3), and epithelial membrane antigen, and negative reactivity for Wilms' tumor 1 gene product. Meanwhile, the tumor stroma was diffusely positive for vimentin. We also review the literature regarding the clinical, imaging, and histopathologic features of this lesion in the pediatric population.
    No preview · Article · Aug 2010 · Journal of Pediatric Hematology/Oncology
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