Mathematical Modelling of Survival of Patients with Glioblastoma following Radical and Palliative Radiotherapy
University of Cambridge, Cambridge, England, United Kingdom Clinical Oncology
(Impact Factor: 3.4).
05/2007; 19(3 Suppl):S35-6. DOI: 10.1016/j.clon.2007.01.381
Available from: Le Zhang
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ABSTRACT: At the dawn of the era of personalized, systems-driven medicine, computational or in silico modeling and the simulation of disease processes is becoming increasingly important for hypothesis generation and data integration in both experiments and clinics alike. Arguably, the use of these techniques is nowhere more visible than in oncology. To illustrate the field's vast potential, as well as its current limitations, we briefly review selected studies on modeling malignant brain tumors. Implications for clinical practice, and for clinical trial design and outcome prediction, are also discussed.
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