Should we continue screening rhesus D positive women for the development of atypical antibodies in late pregnancy?

ArticleinJournal of Maternal-Fetal and Neonatal Medicine 20(1):59-61 · February 2007with13 Reads
Impact Factor: 1.37 · DOI: 10.1080/14767050601123317 · Source: PubMed


    The purpose of this study was to calculate the incidence of the new development of atypical antibodies (other than anti-rhesus D) in women attending for antenatal care, and to assess the clinical impact and cost-effectiveness of a second test to detect these antibodies.
    A three-year retrospective analysis was undertaken to calculate the number of rhesus positive women who developed new antibodies in the last trimester of pregnancy.
    Of 13,143 rhesus positive women, 20 (0.15%) developed new antibodies; fetal outcome was not compromised in any of these cases.
    Repeat testing in late pregnancy would appear an unnecessary expense in our population.