Lung Transplantation for Pulmonary Metastases and Radiation-Induced Pulmonary Fibrosis after Radioactive Iodine Ablation of Extensive Lung Metastases from Papillary Thyroid Carcinoma
Endocrine Surgery Department, University of California, San Francisco, California, USA.Thyroid (Impact Factor: 4.49). 05/2007; 17(4):367-9. DOI: 10.1089/thy.2006.0234
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ABSTRACT: In locally advanced thyroid cancer confined to the neck, lymph node surgery pursues curative intentions but is also performed for the prevention of complications. These complication may arise from the invasion of local structures, such as recurrent laryngeal nerve, compromising quality of life, or trachea and esophagus, which may be life-threatening . The tumor biology of thyroid cancer is mainly determined by the respective tumor type (papillary, follicular, low-differentiated, undifferentiated, and medullary) and the extent of disease (intrathyroidal growth versus extrathyroidal extension; locoregional versus distant metastases). To complicate the matter further, clinical outcome is also influenced by a host of proliferative factors.
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